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Zinacef (Cefuroxime)

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Zinacef is an antibiotic used to treat and prevent a number of bacterial infections. These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease. It is used by mouth or by injection into a vein or muscle.

Other names for this medication:
Altacef, Cefakind, Ceftum, Cefuroxime, Kefurox, Oratil, Pulmocef, Stafcure, Supacef, Zefu, Zinacef, Zocef

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Cefixime, Ceftin, Omnicef, Suprax, Noroxin, Rulide, Duricef

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Also known as: Cefuroxime


Zinacef eye drops and eye ointment are used to treat bacterial eye infections. Eye infections are a common cause of conjunctivitis. In conjunctivitis, your eye becomes inflamed, feels gritty, and may water more than usual. The white of your eye may look red, and your eyelids can become swollen and stuck together with a discharge when you wake up in the morning. Only one eye may be infected to begin with, but it often spreads to both eyes.

Most cases of infective conjunctivitis clear within a few days without treatment. For more severe infections, or for infections which do not clear on their own, an antibiotic eye drop or ointment such as Zinacef can be helpful.

Zinacef works by helping to kill the bacteria which are causing the infection. It is available on prescription. You can also buy the drops and the ointment from a pharmacy, without a prescription, if it is for conjunctivitis in an adult or a child over 2 years of age. Do not use Zinacef eye drops or ointment for a child under 2 years old, unless it has been prescribed by a doctor.


Take Zinacef by mouth with or without food. Swallow Zinacef whole. Do not break, crush, or chew before swallowing. Zinacef works best if it is taken at the same time each day. If you want to achieve most effective results do not stop taking Zinacef suddenly. To clear up your infection completely, take Zinacef for the full course of treatment. Keep taking it even if you feel better in a few days.


If you overdose Zinacef and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zinacef are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur during treatment or within several months after treatment with Zinacef. Do not treat diarrhea without first checking with your doctor.

The tablet and oral suspension forms of Zinacef are not equivalent. Do not substitute one for the other.

Zinacef only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Zinacef for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Zinacef may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Diabetes patients - Zinacef may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Zinacef. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Lab tests, including liver function, kidney function, and complete blood cell count, may be performed while you use Zinacef. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Zinacef should not be used in children younger 3 months; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zinacef while you are pregnant. Zinacef is found in breast milk. Do not breastfeed while taking Zinacef.

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