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Trichomonacid (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

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Also known as: Metronidazole


Trichomonacid (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Trichomonacid is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


In the Female. One-day treatment – two grams of Trichomonacid, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Trichomonacid overdose, Trichomonacid infusion should be discontinued. Patients should be treated symptomatically.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Trichomonacid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Interaction with Alcohol. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole.

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In this model, Clara cell-specific transformation is accomplished by directed expression of the SV40 large T antigen (TAg) under the mouse Clara cell secretory protein (CC10) promoter. Subjects received topical penciclovir for 4 days during successive episodes of recurrent herpes labialis. Mathematical morphology for automatic detection of brain lesions at magnetic resonance imaging. This study aimed how many days after taking flagyl can you drink alcohol to evaluate the anatomical alterations of the cardinal ligaments (CL) and uterosacral ligaments (USL) in women with uterine prolapse by magnetic resonance imaging (MRI) and MRI three-dimensional reconstruction (3DR). However, the detailed mechanism, including regulating molecules, is still unclear.

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We also present findings on transcriptional and translational regulation of HIF-1a via ROS and the interplay with microRNAs in this process. Cilostazol provided a protective effect in the secondary prevention of the chronic phase of ischemic stroke. Patients who completed 1 year (48 weeks) of randomized treatment with TDF or adefovir dipivoxil were eligible to receive open-label TDF for a total duration of 8 years (384 weeks). Statistical-learning methods have been developed for facilitating the prediction of pharmacokinetic and toxicological properties of chemical agents. 30 clinical specimens 18 AH and 12 VF were obtained from 20 eyes with the clinical diagnosis of endophthalmitis. Pulsed laser angioplasty: wavelength power and energy dependencies relevant to clinical application. A nutritional support was indicated in 52 patients, most of whom had deglutition problems linked with post-therapeutic after-effects of neoplasia of the ORL sphere. As CRF has been demonstrated to inhibit GH release, the authors hypothesized that within VFD-reared subjects, animals with relatively high CRF concentrations would exhibit relatively diminished GH responses to clonidine.

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Quantitative measurements of inner echogenic and deeper echolucent layer thickness were determined as well as estimates of ultrasound reflectivity and compared with histologic measurements of intimal and medial thickness and collagen, proteoglycan, lipid and calcium content. Contrast enhancement in primary tumors of the brain and spinal cord. This paper presents a method of headphone/earphone equalization based upon deconvolution of the headphone impulse response from other acoustic filters in the processing chain. The questions included whether the respondent had ever been asked for a prescription by a co-worker and how often the respondent had received such requests and written such prescriptions in the previous three months. However, subpopulation of patients showed delayed improvement following ECTR. Results of this study demonstrated that the electromagnetic decoupling between array elements and the B1 field strength can be improved by using the tilted element method in microstrip RF coil array designs at the ultrahigh field of 7T.

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Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder. Here we describe a mass spectrometric approach for determining levels of acetylation at individual lysine residues within the amino-terminal tail of histone H4. Here we demonstrate that chemotherapy-induced nerve injury in the bone marrow of mice is a crucial lesion impairing hematopoietic regeneration. Induced alterations in metabolism of DL-norleucine-2-C14 in the intact cow. Measurements were done in conscious, unrestrained pigs and with sedated, and analgosedated animals on subsequent days. To identify independent predictors of progression and global survival in patients affected by pT3 renal cell carcinoma. Literature retrieval, trial selection, data collection, and statistical analysis were performed according to the Cochrane Handbook. The present results suggest that decreased expression of GDNF takes some part in development and/or maintenance of neuropathic pain. Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.

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