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Topicil (Clindamycin)
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Topicil

Topicil (generic name: clindamycin; brand names include: Clindatec / Dalacin / Clinacin / Evoclin) is used to treat a wide variety of serious bacterial infections including infections of the respiratory tract, skin and soft tissue, pelvis, vagina, and abdomen. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Topicil kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Other names for this medication:
Acnestop, Aknet, Albiotin, Antirobe, Bexon, Bioclindax, Clendix, Clidacin, Climadan, Clinacin, Clinda, Clindabeta, Clindacne, Clindamycin, Clindamycine, Clindamycinum, Clindastad, Clindesse, Clindoral, Clindox, Clinika, Clintopic, Cliofar, Cluvax, Comdasin, Daclin, Damicine, Derma, Edason, Eficline, Handaramin, Klimicin, Klindacin, Klindaver, Klitopsin, Lanacine, Lindacil, Lindacyn, Lindan, Luoqing, Ribomin, Topicil, Veldom, Ziana, Zindaclin

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Suprax, Biaxin, Sumycin, Terramycin, Ilosone, Amoxil

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Also known as: Clindamycin

Description

Topicil is a prescription medication used to treat bacterial infections of the lungs, skin, blood, bones, joints, female reproductive system, and internal organs.

Topicil belongs to a group of drugs called lincomycin antibiotics. These work by stopping the growth of bacteria.

This medication is available as a vaginal cream, vaginal suppository, oral capsule, and oral liquid.

This medication is also available in injectable forms to be given directly into a vein (IV) or a muscle (IM) by a healthcare professional.

Common side effects of Topicil include nausea, vomiting, joint pain, heartburn, pain when swallowing, and white patches in the mouth.

Dosage

Take Topicil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take the capsule with a full glass of water to keep it from irritating your throat.

Measure the oral liquid with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Topicil is sometimes given as an injection into a muscle, or injected into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

To make sure this medicine is not causing harmful effects, you may need frequent medical tests during treatment.

If you need surgery, tell the surgeon ahead of time that you are using Topicil.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Topicil will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Protect the injectable medicine from high heat.

Do not store the oral liquid in the refrigerator. Throw away any unused oral liquid after 2 weeks.

Overdose

In the event the patient misses a dose of Topicil, the patient should take it as soon as possible. However, if it is almost time for the next scheduled dose, taking another dose of Topicil may cause an overdose which can lead to serious health complications. In this case, the missed dose should be skipped entirely to avoid an overdose potential. If an overdose of Topicil is suspected the patient should seek immediate medical intervention and assessment. An overdose may involve symptoms such as changes in mood or behaviors, thoughts of self harm, suicidal thoughts, seizures, or convulsions.

Storage

Store Topicil at room temperature, between 68 to 77 degrees F (20 to 25 degrees C) in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Topicil out of the reach of children and away from pets.

Side effects

The most common side effects associated with Topicil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Generic Topicil if you are allergic to Generic Topicil components or to to tartrazine. Be very careful if you're pregnant or you plan to have a baby, or you are a nursing mother. Try to be very careful with Generic Topicil if it is given to children younger than 10 years old who have diarrhea or an infection of the stomach or bowel. Elderly patient should use Generic Topicil with caution. Be sure to use Generic Topicil for the full course of treatment. Avoid alcohol. It can be dangerous to stop Generic Topicil taking suddenly.

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Communicating about haemophilia within the family: the importance of context and of experience. Here we review our current understanding of the role of the RANKL/RANK/OPG system in bone and other tissues. The idea that the rings that are the faces of natural tilings form a complete basis set (essential rings) is explored and patterns of catenation of such rings described. A number of assays are under development that will permit the rapid screening of the interaction of coatings with representative marine organisms. weihenstephanensis strains were identified among them when subjected to discriminative PCR assays and growth temperatures which delimit this species. The open reading frame (ORF-401) is capable of encoding a protein of 401 amino acids with a predicted molecular mass of 43 kDa. The Journal of Neurosurgery, begun in 1944, has successfully fulfilled the purposes of its founders. Under the null hypothesis of no difference in adjusted treatment means, we estimated actual significance levels by comparing observed test statistics to appropriate critical values from the F- and t-distributions for nominal significance levels of 0.10, 0.05, 0.02 and 0.01.

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There has been a large decrease in the risk of tuberculous infection in Kabul since the last assessment. Effect of (D-Met2, Pro5)enkephalinamide, a highly potent opiate agonist, on the drinking behaviour of rats. Subsequently, one group of rats was deprived of alcohol for 1, 3, 7, 15, 30, 90 or 180 consecutive days, while the second group had continuous access to alcohol (deprivation phase). Ex vivo study of transdermal permeation of four diclofenac salts from different vehicles. Prior to CEA, FDG-PET, black-blood T1-weighted imaging (BB-T1WI), and 3-dimensional time-of-flight (TOF) imaging were performed. Dehydrogenases were shown to be still present by triphenyltetrazolium chloride (TTC) reaction, but the anti-actin antibody reaction had disappeared in areas corresponding to the ischemic sites. Although parental pairs of a child with autism were more likely than comparison parental pairs to have both parents characterized by the presence of the BAP, they more commonly consisted of a single parent with BAP features. Antinuclear antibodies and anti-SS-A/Ro antibodies were present. Mostly drug induced, this condition can also be caused by other factors. To investigate the treatment of perioperative period on maxillofacial patients with diabetes.

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Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus. Wrapped around this strategy is an adherence program that assesses adherence and provides treatment support by helping patients overcome the myriad barriers to adherence. Effect of pollen extracts (cernitin preparation) on selected biochemical parameters of liver in the course of chronic ammonium fluoride poisoning in rats. Alternatively, here, we show that under in situ elastic bending deformation at room temperature inside a 300 kV high-resolution transmission electron microscope, a normally electrically insulating multiwalled BN nanotube may surprisingly transform to a semiconductor. Research evidence has indicated that dysregulation of cell polarity proteins may play an important role in cancer development. Classification of lupus glomerulonephritis by ISN/RPS 2003: points of classification and the diagnostic manual. Inhibition of growth of Chlamydia trachomatis by nonoxynol-9 in vitro. Confounding by indication is a special case and results from the fact that in medical practice the choice between intervention alternatives is dependent on the perceived prognosis of the patient for whom these interventions are considered. Troponin dosage and measurement of right upon left ventricular diameter ratio (by echocardiography or CT-scan) are mandatory in the prognostic evaluation of submassive forms (i.e.

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Low-molecular-weight heparins in acute coronary syndrome: acquired results and new perspectives. A longitudinal study based in the two largest HIV natural history cohort studies conducted in 7 metropolitan areas of the United States. An analysis of more than 1000 research articles in biology reveals that the name of the species being studied is not mentioned in the title or abstract of many articles. US and Canadian programmes were leaders in applying computerized data management to newborn screening in the 1980s. When compared with SRSV-9 (Tokyo/SRSV/86-510) reported previously (Hayashi et al, J. Traumatic coronary pseudoaneurysm has been described to be mainly associated to iatrogenic lesion of the coronary arteries. Examining the Economic and Political Characteristics of the Grey-to-Green Continuum. The task now is to better understand the roles of cross-age consistency in caregiver behavior and the structure of mental representations of early experience in stability and change.

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JDW also showed the suppressed nitrite production in ST-treated pancreatic islet cells. Therefore, biopsychosocial aspects should be integrated into current somatically oriented models of medical support. The techniques most commonly used to estimate intra-abdominal pressure are measurements of bladder and gastric pressures. Analysis of the intact samples at their anchorage sites revealed that annular subbundle fibrils penetrate beyond the cement line to a limited depth and appear to merge with those in the vertebral and cartilaginous endplates. Dietary fat and adipose tissue metabolism in ruminants, pigs, and rodents: a review. She had been using inhaled corticosteroids and bronchodilators and presented five exacerbations of COPD due to pneumonia in the same year, with hospitalizations in March and September. Passive transmission and persistence of naturally acquired or vaccine-induced maternal antibodies against measles in newborns. WITHDRAWN: Antihypertensive therapy for preventing cardiovascular complications in people with diabetes mellitus.

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Decreased binding of 11C-SA4503 corresponded to a loss of sigma1-receptors from the tumors. Developmental origins of life history: growth, productivity, and reproduction. The importance of quality of life is a major factor with regard to management of therapy. Cardiomyocytes and murine embryonic fibroblasts were administered NO (10-1200 nM) during simulated ischemia, and cell death was assessed during reperfusion without NO. This effect was also not well correlated with inhibition of 3H-DA uptake. Both nutrient restriction of the adult dam and overnourishment of the adolescent dam during pregnancy suppress placental cell proliferation and vascularity. Fifty consecutive Herbst patients treated with reduced mandibular splints (RMS) were compared to 182 consecutively treated Herbst patients with total mandibular splints (TMS).

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Use of a soft sensor for the fast estimation of dried cake resistance during a freeze-drying cycle. Functional analysis of the epidermal-specific MYB genes CAPRICE and WEREWOLF in Arabidopsis. Expression of interferon-induced genes in different tissues of mice. It was further demonstrated that untreated pain can have long-lasting physiologic and neurodevelopmental consequences. Levels of apoC-III were decreased, which suggests that ciprofibrate belongs in the group of fibrates that influences lipoprotein metabolism through PPAR-alpha activity. To assess the correlation between H pylori colonization of tonsillar tissue in chronic tonsillitis and in noninfectious hyperplastic tonsils. The enhanced binding and cytotoxicity of IL 1-treated target cells was only observed when the latter cells were preincubated with IL 1 at 37 degrees C, and was not evident at 4 degrees C. This article discusses the advantages and disadvantages of the more common CT perfusion protocols and offers proposals that could allow for easier comparison between studies employing different techniques. Similar to previous reports, individuals with PNES reported poorer HRQOL than those with ES.

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These findings may explain how ER status controls epithelial-to-mesenchymal transition in human breast tumors. Preliminary investigation of viable Lactobacillus acidophilus instillation in vaginal pruritus. Although no recurrence was noticed in the right eye, recurrence of the conjunctival intraepithelial neoplasm lesion was noticed in the left eye. Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. To identify the effects of indium on the lung and to assess exposure-effect and exposure-response relations between indium exposure and effects on the lungs. The above-mentioned regions of the CR were of great importance in the organization of sanitary-hygienic and antiepidemic measures, as it is on the territories of these regions that the camps with many thousands of persons, forced to move temporarily from Grozny and other regions affected by hostilities, are concentrated. We hypothesize that reach tasks are controlled by a set of feedforward and feedback descending commands for trajectory and final posture, respectively. A Benzothiazole-Based Sensor for Pyrophosphate (PPi) and ATP: Mechanistic Insight for Anion- levaquin oral tablet 500 mg Induced ESIPT Turn-On.

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Ultrasound examination is the primary imaging investigation used in initial evaluation of the symptomatic testis. In gel shift assays binding of calmodulin to ZmSAUR2 was demonstrated, suggesting the possibility of post-transcriptional regulation. The aim of this study was to examine sludge accumulation in relation to surface characteristics designed by nanotechnology. Probabilities were obtained by literature review, and health-related quality of life was evaluated by asking 30 orthopedic experts to complete a questionnaire. Lack of a relation between serum potassium concentration and exercise hyperpnea in patients with chronic heart disease. Membrane proteins correlated with expression of the polysialic acid capsule in Escherichia coli K1. In the Amerlite MAB FT4 assay, as stated by the manufacturer, FT4 values should be normal in patients with anti-thyroid hormone autoantibodies. Rifaximin is an oral rifampin analog, and its activity is targeted within the gastrointestinal tract. We have identified suitable reference genes for miRNA-qPCR in Atlantic salmon. The diagnosis of uterine artery pseudoaneurysm was made by color and duplex Doppler ultrasonography (CDDUS) and confirmed by arteriography.

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Cell-free platforms for flexible expression and screening of enzymes. Dentists should strictly follow instructions by the manufacturers because failure of materials can mostly be blamed on the clinician rather than on the material. Iron and zinc deficiency are prevalent during infancy in low-income countries. This technology has great promise in not only diagnosing peripheral lung lesions with greater accuracy, but also may provide a means for therapeutic interventions through this minimally invasive technique. Acid tolerance response of biofilm cells of Streptococcus mutans. Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. Application of the Empirical Mode Decomposition to the analysis of esophageal manometric data in gastroesophageal reflux disease.

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Our data suggest that the results of segmental hair analysis should be carefully examined in pregnancy. Systemic endothelium-dependent vasoreactivity predicts recurrence of instability and cardiovascular event rates in patients with ACS. The evaluation provides guidance as to what percentage of the control effect needs to be preserved so that through noninferiority testing of effect retention one can assert the treatment efficacy within a desired level of the error rate. Furthermore, when expressed in yeast, human PIF1 suppressed both G-quadruplex-associated DNA damage and telomere lengthening. It is essential that all paediatric and emergency departments accepting children with burns are aware of the symptoms, signs and early management of TSS. It equips clinicians and scientists with a useful tool in studying molecular mechanism of human diseases using modern high-throughput genome-wide screening strategy, which assists personalized therapy. The effect of antibiotic and probiotic combination therapy on secondary pancreatic infections and oxidative stress parameters in experimental acute necrotizing pancreatitis. In large observational studies, beta- carotene reduced the risk of IHD events in men, particularly in smokers. Knowledge, attitudes, and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. This article reviews the pathophysiology and management of bleeding peptic ulcer.

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