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Taclar (Clarithromycin)
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Taclar

Taclar is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection.

Other names for this medication:
Bacterfin, Biclar, Bicrolid, Clacee, Clarimac, Clarimycin, Clarithromycin, Claritrox, Clarogen, Claromac, Clarosip, Claryl, Clasine, Clathrocyn, Clonocid, Egelif, Eliben, Emimycin, Eracid, Euromicina, Fromilid, Geromycin, Italclar, Kalixocin, Karin, Klarifor, Klarit, Klaritpharma, Klerimed, Kleromicin, Laricid, Macrobid, Macrol, Odycin, Rocin, Taclar

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Also known as: Clarithromycin

Description

Taclar (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Taclar works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

Taclar Filmtab and Taclar Granules may be given with or without food.

Taclar XL Filmtab should be taken with food. Swallow Taclar XL Filmtab whole; do not chew, break or crush Taclar XL Filmtab.

Triple therapy: Taclar Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Taclar Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Taclar Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Taclar Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Taclar Filmtab/omeprazole. The recommended adult dosage is 500 mg Taclar Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Taclar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Cauterization of hydrosalpinges before in vitro fertilization is an effective surgical treatment associated with improved pregnancy rates. Numerous medical co-morbidities and medications can alter testosterone levels resulting in a wide range of nonspecific clinical signs and symptoms of TD. Mucosal atrophy of the jejunum is caused by endogenous opioid in fasting rats. Quit1 mRNA was specifically expressed just after starvation of cells at around the PS point, thus indicating the importance of CAR1 for cellular differentiation as well as the actual existence of the PS point. Resistance to penetration at the epidermis is a key component of basal defence against disease and critically depends on fortification of the cell wall at the site of attempted penetration through the development of specialised cell wall appositions rich in antimicrobial compounds. The observed association of the 1p13.3 locus with all-cause mortality requires confirmation in further studies. In this report, we compare the long-term outcome of pediatric liver transplantation (LTx) patients maintained with tacrolimus-based and with cyclosporine (CsA)-based immunosuppressive therapy. Amyloid deposits may progressively reduce corneal sensitivity and damage epithelium and stroma.

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A perfluorochemical emulsion for prehospital resuscitation of experimental hemorrhagic shock: a prospective, randomized, controlled study. Studies of the hooked tail current amplitude and the degree of the stationary current inhibition dependence on the blocker concentration led to a new method for estimation of fast foot-in-the-door blocker binding/unbinding rate constants. The somnogenic cytokine growth factors (SCGF) in turn, induce molecules necessary for synaptic connectivity. Infusion of adrenaline to fetuses caused a progressive decline in arterial O2 saturation (Sa, O2), pH and base excess, but no change in arterial partial pressure of O2 (Pa,O2) or CO2 (Pa,CO2). During their differentiation under these conditions the 3T3-C2 cells develop markers typical of adipose cells: glycerophosphate dehydrogenase, ATP-citrate lyase, fatty acid synthetase and glycerophosphate acyltransferase. Following intracerebral hemorrhage (ICH), high-mobility group box 1 protein (HMGB1) may promote neurogenesis that supports functional recovery. Multi-frequency EPR spectroscopy further reveals the presence of at least one intermediate tryptophanyl radical center in activated AauDyPI with W377 as the most likely candidate.

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Strain among nurses and their emotional reactions during 1 year of systematic clinical supervision combined with the implementation of individualized care in dementia nursing. PET tumour delineation by COA showed a good correlation with pathological findings. Results indicated that participants experienced a significant reduction in thin-ideal internalization, body dissatisfaction and dieting intentions across the course of the program. Two UC cell lines, NTUB1 and a cisplatin-resistant subline N/P(14), were applied to examine the cytotoxic effect of NVP-BEZ-235. In this study we have established a rapid and sensitive technique for the simultaneous detection of intracellular IL-2 in conjunction with CD3.

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Effects of estrogen on response to edetic acid infusion in postmenopausal osteoporotic women. Synthesis of twist-twist pi-conjugated di-sec-alkylstilbenes and stilbene polymers. Crystals of the cell-binding module of fibronectin obtained from a series of recombinant fragments differing in length. Analysis of ethnographic data and 38 semi-structured interviews with staff indicated that the agencies were in practice using very similar methods. An intraperitoneal injection of IL-1 (1 microgram/rat) accelerated NE turnover in the spleen, lung, diaphragm, and pancreas without appreciable effects in other organs examined. It is likely that recombinational events between topoisomerase genes from related species of streptococci contribute to the spread of FQ resistance in S. In particular, I will review studies that demonstrate how different types of mutations, from the replacement of individual amino acids to the shuffling of modular domains, lead to markedly different evolutionary trajectories and consequently to diverse network rewiring. Animal studies indicate that intracellular calcium handling is altered before LVH develops.

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Neuropsychological impairment in multiple sclerosis patients: the role of (juxta)cortical lesion on FLAIR. Modification of a technic of temporary osteosynthesis in cases of diaphysial fractures. Associated vertebral fractures (12 per cent) were identified during the first three months after the injury, but no deformity progressed after three months. These are the first results that demonstrate at least two distinct aspects of thermotolerance. No therapeutic effect was obtained if UCB-MSC were administered at onset of GVHD. Direct comparison of new and established modalities in a single study population has major advantages over randomized controlled trials, which are extremely costly and time-consuming and are not appropriate for most evaluations of diagnostic modalities. Cellular organelles (chloroplasts and mitochondria) represent the final stages of integration of endosymbionts. Here, I highlight a growing body of research illustrating an important link between environmental conditions and divergent reproductive strategies in zooplankton. Assessment of dependent location of a mural nodule within the cavity and wall thickness of the cavity itself can also be helpful for differentiation.

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1) alternate etiologies for increased tone and 2) injection with botulinum toxin within the 6 months preceding the study. Using model membrane-inserted hydrophobic helices to study the equilibrium between transmembrane and nontransmembrane states. Mechanical perforation with the 100 microns fibre occurred four times, but there were no haemodynamic sequelae. The levels of cocoa aroma compounds formed during roasting are shown to vary directly with bean fermentation time and inversely with residual procyanidin content in cocoa liquor. An NO donor (NOC18) suppressed shear-induced activation of PKC-epsilon and ERK1/2, and also repressed MCP-1 induction. Impact of endothelin-1 in endotoxin-induced pulmonary vascular reactions. Using transgenic mice, we show that hepatic TGF-beta1 overexpression inhibits abundance of the cyclin-dependent kinase activating tyrosine phosphatase cdc25A protein. Dilution of alveolar gases during nitrous oxide excretion in man. Of the 7 materials believed to be non-sensitizers, 5 were negative in the LLNA and 2 produced positive results. No significant differences between the two treatments were observed on PPI, although escitalopram was found to significantly delay habituation of the ASR.

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Xenobiotic-metabolizing enzymes as autoantigens in human autoimmune disorders. In this article, we report the identification of a novel MAR-binding protein, named SMAR1, that also binds MARbeta. Increased phosphorylation of extracellular regulated kinases (ERK1/2) is required for PGE(2) to stimulate cell proliferation of human colon cancer cells. Isolation of cytopathic and noncytopathic bovine viral diarrhea virus from the spleen of cattle acutely and chronically affected with bovine viral diarrhea. Evaluation of the National Notifiable Disease Surveillance System in Taiwan: an example of varicella reporting. Overall, fewer than 20 cases have been described in the literature.

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MR imaging demonstrates abnormalities of the rhinencephalon present in KS patients and occasionally absent in IHH patients. Most cases of congenital eversion of the upper eyelids resolve spontaneously within two weeks of birth. Application of the definition of biological species to orbiviruses enables consideration to be given the evolutionary tendencies of virus populations and to mechanisms for generating diversity within orbiviruses. The guanine protects the organic channels as buffer/and H getter layer between the channels and capping Al2O3, whereas the oxide capping resists ambient molecules. Adapalene is a novel chemical entity which, in terms of pharmacology, behaves similar to tretinoin, but is chemically and photochemically stable.

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Extensive areas of lipohypertrophy at the insulin injection sites on both thighs, upper arms and buttocks had developed in a 22-year-old woman with type 1 diabetes. Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5). Dissecting the determinants of depressive can you drink alcohol with rulide disorders outcome: an in depth analysis of two clinical cases. Previously, we reported that specific aromatic amines and ethyl paraoxon (the metabolite of the insecticide ethyl parathion) induced enhanced mutagenic responses in Salmonella typhimurium. Overcoming Barriers to Increase the Contribution of Clinical Psychologists to Work With Persons With Severe Mental Illness. Structurally, ionophore and fluorophore are two essential parts determining the resultant performance of the chemosensor. Historical aspects of a local cluster of individuals with lysinuric protein intolerance (LPI) were studied in a sample of patients and in a mass-screened population in a northern area of Japan. Additionally, primary tumors were shown to express significant levels of mature beta gene mRNA. We utilise this method to probe the dynamics of intact sperm and nuclear envelope precursor membranes. The results suggested that opportunistic infections in immunocompromised patients could be caused by both virulent and avirulent R.

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Posterolateral rotatory instability of the elbow with insufficient coronoid process of the ulna: a report of 3 patients. Decreased salivary output is a definite objective sign, but oral mucosal wetness is a more reliable factor for the evaluation of xerostomia. High-quality genotyping data from formalin-fixed, paraffin-embedded tissue on the drug metabolizing enzymes and transporters plus array. The narrow width of the photoluminescence emissions of different colours (blue to red) make these nanocrystals a potential candidate for different optical and optoelectronic devices. The atypical 1,4-benzodiazepine, Ro5-3663, a GABA antagonist which may act at the picrotoxinin site, produced a dose-related reduction in food consumption. The selected isolates were screened in vitro for activities related to plant nutrition and plant growth regulation as well as for antifungal and nematicidal traits. To investigate the effects of knee osteoarthritis (OA) on activities of daily living and motor and functional improvement in stroke patients with hemiparesis. Recurrent D-lactic acidosis with encephalopathy in a boy with short-bowel syndrome.

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