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Synclar (Clarithromycin)

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Synclar is used in various infections on the body like the skin, soft tissue, chest and stomach infections. It contains clarithromycin which is an antibiotic medicine. It acts by stopping the multiplication of bacteria.

Other names for this medication:
Abbotic, Aeroxina, Biclar, Clabel, Clarimycin, Claripen, Clariston, Claritab, Clarithromycin, Claritrox, Clariva, Clariwin, Clarix, Clarogen, Claromac, Claromycin, Clathrocyn, Clatic, Cleanomisin, Clonocid, Clormicin, Egelif, Emimycin, Euromicina, Finasept, Geromycin, Hecobac, Heliclar, Helimox, Helozym, Infex, Kailasa, Klabion, Klarifor, Klarimac, Klazidem, Klerimed, Klonacid, Krobicin, Laricid, Larithro, Laromin, Lekoklar, Macrol, Nutabact, Rocin, Rolicytin, Uniklar, Zeclar

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Also known as: Clarithromycin


Synclar (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Synclar works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


Synclar Filmtab and Synclar Granules may be given with or without food.

Synclar XL Filmtab should be taken with food. Swallow Synclar XL Filmtab whole; do not chew, break or crush Synclar XL Filmtab.

Triple therapy: Synclar Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Synclar Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Synclar Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Synclar Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Synclar Filmtab/omeprazole. The recommended adult dosage is 500 mg Synclar Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store Synclar at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Synclar out of the reach of children and away from pets.

Side effects

The most common side effects associated with Synclar are:

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Monitoring of weekly virus isolates by PAGE demonstrated genome segment diversity among BTV serotype 11 isolates and an individual bull simultaneously infected with multiple electropherotypes of this serotype. The epididymal fat pad as a transplant site for minimal islet mass. Suicidal hanging resulting in complete decapitation--forensic, radiological, and anthropological studies: a case report. The molecular basis of chaperone-mediated protection against neurodegeneration might lead to the development of therapeutics for tauopathies. Epithelioid variants have only been described in two patients and only one of these had a multifocal presentation. Strain patterns in cervical enamel of teeth subjected to occlusal loading.

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The larvae, 3 in number, were observed in the bulbar conjunctiva and the symptoms of the eye improved within a few hours of their removal. The method consisted of in vitro stimulation with phytohemagglutinin (PHA) for 2 days, followed by culture with a low dose of recombinant human interleukin-2 (rIL-2) for 6 to 10 days. In situ reaction rate measurements help to define the role of product inhibition in the asymmetric alkylation of benzaldehyde with diethylzinc using (-)-MIB as a chiral reagent. When platelets were subjected to subcellular fractionation, essentially all of the platelet-associated collagenase inhibitor was found to be located in the alpha-granule. Furthermore, vaccination rate among IBD patients in Korea has never been investigated. These data show that TcII is distributed in the five main Brazilian biomes and is likely more prevalent than currently described.

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The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity. In this prospective study, we included 616 healthy singleton fetuses. By recognizing adolescent females with depressive symptoms, providers can strategize their approach to effective contraception counseling. The results of reverse transcriptase-polymerase chain reaction and Western blot analysis revealed that MAK-V/Hunk is expressed endogenously in mDCT cells. We used THP-1 human promonocytes, which mimic gene silencing when rendered endotoxin-tolerant in vitro, to test whether TNFalpha proximal promoter nucleosomes and transcription factors adapt to an activation-specific profile by developing characteristic chromatin-based silencing marks. Common biochemical defects linkage between post-traumatic stress disorders, mild traumatic brain injury (TBI) and penetrating TBI.

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Gastroesophageal reflux may have precipitated the development of esophageal pemphigus. Differences between endosteal and periosteal cells both in percentage of cells labeled and magnitude of labeling were maximum in control animals and progressively decreased with increasing periods of hibernation. Antipsychotics have higher binding affinity to D2 subtype of dopamine receptor. Prospective data on the outcomes of children exposed to chemotherapy in utero are limited for the breast cancer population. Although regimens containing two protease inhibitor (PI) together with ritonavir boosting are used with the aim of improving virologic response to salvage therapy, there is little evidence to support or reject this approach. Aspergillus-induced exogenous allergic alveolitis in a rural gardener. The most common dental emergency with which patients presented at an emergency rota service was periapical periodontitis, followed by pulpitis and fractured tooth. White matter abnormalities in patients with treated hyperphenylalaninaemia: magnetic resonance relaxometry and proton spectroscopy findings. The hypertensive effect of an intravascular infusion of angiotensin II is substantially reduced by isoflurane anaesthesia. Cyclic tetrapeptides containing trifluoromethyl and pentafluoroethyl ketone as zinc binding functional group were synthesized as potent HDAC inhibitors.

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Eco-epidemiological factors contributing to the low risk of human exposure to ixodid tick-borne borreliae in southern California, USA. Sunflower trypsin inhibitor (SFTI-1) derived peptide having one disulfide bond could be immobilized via a thiol-disulfide exchange reaction onto a gold surface on a quartz crystal microbalance (QCM) chip. Integrins function in cell invasion by mediating cell movement on matrix molecules and also by regulating the expression of matrix-degrading enzymes, namely the matrix metalloproteinases. Depression in the elderly looks like depression in adulthood, without mention of a strict clinical specificity. Chromosomal analysis involving the fluorescence in situ hybridization method revealed a microdeletion of 22q11.2. After the cells were harvested at the specified time points, the mRNA and protein levels of ABCA1, ICAM-1 and MCP-1 were detected by RT-PCR and Western blotting, respectively. Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.

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The developed carboxymethyl cellulose/ZnO nanocomposite hydrogels can be used effectively for biomedical application. The present findings unveil the missing step of the cardiolipin synthesis pathway in mitochondria as well as the flexibile regulation of phospholipid biosynthesis to respond to compromised CDP-DAG synthesis in mitochondria. This functional magnetic resonance imaging (fMRI) study explores the neural correlates of contamination/washing-related OCD with a highly individualized symptom provocation paradigm. Cinefluorography in the pre- and post-operative management of laryngeal cancer. The significant masked feature priming effect that was observed in both experiments converges with the empirical evidence in the speech production and visual word recognition domains indicating a functional role for features in reading aloud. Blood ammonia was well metabolized by 20 g hepatocytes, but the other functions such as glucose concentration, total bile acid concentration, and survival time required 30 g hepatocytes to improve conditions. Using traditional methods only to investigate whether interventions are effective or not could not provide appropriate lessons. Seven dogs were submitted to resection of a segment of the esophageal wall, which was then corrected by suturing a pediculated diaphragm flap.

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The separation of basic solutes at low pH by capillary electrochromatography (CEC) has been investigated. The envelopes of amphibian oocytes: physiological modifications in Bufo arenarum. The value of percutaneous coronary intervention in aortic valve stenosis with coronary artery disease. There is good evidence that women refusing HIV antenatal screening have a higher prevalence of another blood-borne virus, indicating clearly that further effort must be made to increase the screening uptake and fully integrate HIV screening with other antenatal tests. NMDA--an excitatory amino acid--, or bicuculline--a GABAA antagonist--injected into the IC mimicked the effects of its electrical stimulation. Indeed, in vitro DNA binding assays revealed that a substantial number of the mutants were specifically defective in the ability to bind cooperatively with alpha 1.

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In the granulation tissue and fibrotic areas around necrotic cancer tissue, they were increased in size and number. Fibrinogenolysis by a neutrophil membrane protease generates an A alpha 1-21 fragment. Hematologic evidence of TTP developed 3 to 9 days after surgery. As part of the safety assessment of these therapeutic agents, a battery of genetic toxicology studies was conducted. A proportion of the active drug and excipient coating are known to embolize distally, but until now zithromax dosing , there have been no reports of adverse events resulting from their use.

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An iron-based T1 contrast agent made of iron-phosphate complexes: in vitro and in vivo studies. Biofilm formation processes in water treatment and distribution are studied using adenosinetriphosphate (ATP) as the parameter for active biomass. Many parents and children utilize the Internet for health-related information, but the quality of these websites can vary. The temperature dependence of the bandgap is the same for both sample types, being measurably different from that of bulk silicon because of quantum confinement. An in vivo xenograft study revealed that WYC02-9 enhanced MAP2K3/6 and MAPK14 phosphorylation, induced apoptosis, and suppressed CRC tumor growth. Some more about unfavourable how much does cleocin cost without insurance results after corrective surgery as seen in leprosy.

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This reduction was due to a significant decrease in the mitotic rate of type-2 cells only, since type-1 NPCs did not show changes in the proliferation index. In this article, the regeneration strategies for tooth and periodontal tissue using tissue engineering concepts. Down-regulating glypican-3 expression: molecular-targeted therapy for hepatocellular carcinoma. Fasting blood glucose levels, hypertension, and WC are the most significant risk factors predicting the risk of ED. To deal with the possible broken vessels, a vascular cross-sectional tree repairing and interpolation algorithm is then developed based on the 3D connectivity and root-converging properties of the tree branches. Anterior decompression of the thoracolumbar spine for chronic pain after thoracolumbar fractures is a safe and effective treatment for patients with this uncommon and difficult problem.

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National sample survey organization survey report: An estimation of prevalence of mental illness and its association with age in India. There may be a period early after brain damage during which marked neural structural changes can occur in the presence of adequate behavioral demand. The same improvements in spatial memory in ethylcholine aziridium-treated rats were observed following intranasal administration of 25 microg/kg and 12.5 microg/kg of vasoactive intestinal peptide loaded by unmodified nanoparticles and wheat germ agglutinin-modified nanoparticles, respectively. A group of 74 students from Weill Cornell Medical College-New York and 32 from Weill Cornell Medical College-Qatar completed pre- and post-clerkship questionnaires assessing their attitudes toward psychiatry. The technique involves moving the photon beam in three steps to degrade its penumbra to match that of the electron field. Multiresistant strains are increasingly common in the hospital environment and there is concern that the infections will become difficult or impossible to treat. It appears possible to assess a process in this model called committed action, and this process appears related to important aspects of functioning. Conclusively, in pups the CPV type 2b vaccine seems to be safe as far as natural immune responses are concerned, while its immunogenicity is preserved. MT cleocin t gel vs lotion did not alter GHRH- or ghrelin-induced GH and/or PRL secretions, suggesting that MT may activate similar signaling pathways as ghrelin/GHRH.

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Evidence for an angiotensin-converting enzyme (ACE) polymorphism in the crayfish Astacus leptodactylus. Further toxicological analyses of glycolic and oxalic acids in serum and urine samples were performed by ion-chromatography (IC) method and showed high values in spot urine and serum ultrafiltrate at admission, but during therapy the values progressively decreased. Evidently, beliefs about the etiology of smoking influence a range of attitudes related to smokers and smoking related policies. The contributions to this special issue of Mutagenesis have been selected to cover the main research areas served by the comet assay, namely genotoxicology, environmental toxicology, human biomonitoring and fundamental investigations into mechanisms of DNA damage and repair. Eosinophilia and polyneuropathy fish antibiotics biaxin after percutaneous transluminal coronary angioplasty. An observational study was undertaken linking the data from seven diabetes retinal screening programs across the U.K.

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