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Sofasin (Norfloxacin)
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Sofasin

Sofasin is used to treat certain types of infections, including infections of the urinary tract and prostate (a male reproductive gland). Sofasin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. Antibiotics will not work for colds, flu, or other viral infections.

Other names for this medication:
Apirol, Asudufe, Baccidal, Bacfamil, Bacteriotal, Bactracid, Baxicin, Bexinor, Chibroxol, Epinor, Esclebin, Firin, Flobarl, Floxamed, Floxatral, Foxgoria, Janacin, Lexiflox, Menorox, Negaflox, Niterat, Nofocin, Nofxan, Noraxin, Norbactin, Norflodal, Norflohexal, Norflok, Norflol, Norflomax, Norsol, Norzen, Notler, Noxacin, Nufloxib, Oranor, Ovinol, Renoxacin, Senro, Shinun, Taflox, Uriflox, Urofos, Uroquin, Uroseptal, Vetamol, Wenflox

Similar Products:
Cleocin, Chloromycetin, Rulide, Keflex, Biaxin, Cefixime, Avelox, Floxin, Vantin

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Also known as: Norfloxacin

Description

Sofasin comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Sofasin. Take Sofasin at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Sofasin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Sofasin at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Sofasin. If your symptoms do not improve or if they get worse, call your doctor.

Take Sofasin until you finish the prescription, even if you feel better. Do not stop taking Sofasin without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Sofasin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Sofasin is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take Sofasin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent crystals from forming in the urine.

Take Sofasin on an empty stomach 1 hour before or 2 hours after eating a meal, drinking milk, or eating a dairy product such as yogurt or cheese.

If you are being treated for gonorrhea, your doctor may also have you tested for syphilis, another sexually transmitted disease.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Sofasin will not treat a viral infection such as the common cold or flu.

Overdose

If you overdose Generic Sofasin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Sofasin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Taking norfloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward. These problems may affect tendons in your shoulder, your hand, the back of your ankle, or in other parts of your body. Tendinitis or tendon rupture may happen to people of any age, but the risk is highest in people over 60 years of age. Tell your doctor if you have or have ever had a kidney, heart, or lung transplant; kidney disease; a joint or tendon disorder such as rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function); or if you participate in regular physical activity. Also tell your doctor if you have ever had any tendon problems during or after your treatment with norfloxacin or another quinolone or fluoroquinolone antibiotic. Tell your doctor and pharmacist if you are taking oral or injectable steroids such as dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), or prednisone (Sterapred). If you experience any of the following symptoms of tendinitis, stop taking norfloxacin, rest, and call your doctor immediately: pain, swelling, tenderness, stiffness, or difficulty in moving a muscle. If you experience any of the following symptoms of tendon rupture, stop taking norfloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or bear weight on an affected area.

Taking norfloxacin may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death. Tell your doctor if you have myasthenia gravis. Your doctor may tell you not to take norfloxacin. If you have myasthenia gravis and your doctor tells you that you should take norfloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment.

Talk to your doctor about the risks of taking norfloxacin.

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Design, dissemination, and evaluation of an advanced communication elective at seven U.S. Although RGD values deviate substantially from unity as a function of projection angle, the RGD averaged over all projections in a complete tomosynthesis study varies from 0.91 to 1.01. Data from 10 road sediments confirm Pt contamination, with a median concentration of 33 ng g(-1) and a range of 15-160 ng g(-1). We report the case of a pseudoaneurysm within a stent with diffuse restenosis, treated with implantation of a pericardium-covered stent, followed by postdilation with a paclitaxel-eluting balloon. In this paper, we show that Tpr import was mediated by the most abundant import receptor, KPNA2, which binds the bipartite NLS in Tpr with nanomolar affinity. Thus far, proof of principle has been obtained from studies in numerous animal models for a variety of human diseases including cancer, reperfusion injury, and inflammatory conditions such as rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. Widely invasive FC still exists and may cause considerable morbidity in patients as young as the third decade of life. Posterior vitreous injection of Hyaluronidase (20 IU) combined with Plasmin (1 IU) can produce complete posterior vitreous detachment.

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Effects of cadmium on differentiation and cell cycle progression in cultured Xenopus kidney distal epithelial (A6) cells. Behavior as a tool for welfare improvement and conservation management in the endangered lizard (Gallotia bravoana). There were no consistent differences in the antibody profiles in patients with sarcoidosis and healthy subjects. Four types of scintigraphy patterns were noted in lymphocele in a total of 13 patients. A radiographic study of posterior apical root resorption in orthodontic patients. Co-expression of functional Ctr1 monomers fused with either cyan or yellow fluorescent protein resulted in fluorescence resonance energy transfer (FRET), which is consistent with multimer assembly of Ctr1. Each of the 6 categories shows characteristic combinations of 3 cardinal radiologic features. Viper and cobra venom neutralization by beta-sitosterol and stigmasterol isolated from the root extract of Pluchea indica Less. The temporal characteristics of ultrashort hard-x-ray pulses generated in a femtosecond-laser-driven x-ray diode are investigated for what is believed to be the first time.

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Two different surgical methods for basal joint arthrosis (implantation of a Swanson condylar prosthesis and resection arthroplasty) are compared. Early onset colonization occurred in 16 of 22 patients colonized by aerobes and in 8 of 15 patients colonized by anaerobes. E2, ICI-182780, and G1 but not E2-BSA significantly up-regulated ROCK-2 expression, which was suppressed by actinomycin-D, PTX, AG-1478, and G-15. Although this structure, known as social balance, is well understood, it is not clear how such factions emerge. The analysis of experimental data by this model shows that metabolic stability-constant levels of phosphocreatine, ATP and inorganic phosphate-at increased energy fluxes is an inherent property of the compartmentalized system. In the present study, the death process of germ cells has been characterized by depleting both FSH and testosterone by administering two different potent GnRH antagonists, Cetrorelix and Acyline to both rats and mice.

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A more active role for the dentist as a preventive agent is advocated to combat the spread of acquired immunodeficiency syndrome (AIDS). Each site in the crystal contains a molecule in one of six different basic orientations with equal probability. National death certificate data on CJD were used (CJD coded as 046.1 for ICD-9 and A81.0 for ICD-10). In reviewing 54 cases of granulomatous hepatitis (GH) diagnosed among 2,620 laparoscopies, we have been able to classify the capsular GH changes into five patterns: Macular, exudative, pinpoint, granular and cord-like. Studies on the etiology, pathogenesis and therapy of experimental myocarditis and arthritis in the dog. Genotoxic stress only affects PIDD isoform 3 mRNA levels, whereas isoforms 1 and 2 mRNA levels remain unchanged. The MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria.

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Single-cell dosimetry for radioimmunotherapy of B-cell lymphoma patients with special reference to leukemic spread. Iatrogenic Cushing syndrome induced by oral and parenteral corticosteroid administration is a well-known complication, and necessary precautions have to be taken. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5. Its aim is to promote discussion about this vital aspect of patient care. Cardiac resynchronization and implantable cardioverter defibrillator therapy: preliminary results from the InSync Implantable Cardioverter Defibrillator Italian Registry.

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Interestingly, we also observed U-II immunoreactivity in crescents. The various changes in the glenohumeral and acromioclavicular joints are described. Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the gestational iodine cohort. We describe a case of intrathoracic ancient neurilemmoma undergoing a malignant change in a 39-yr-old man. Syndecan-1 (Sdc-1) is a member of a family of cell surface proteoglycans, which has been reported to participate in the regulation of events relevant to tissue repair and chronic injury responses, including cell-substrate interactions, matrix remodeling, and cell migration. Molecular targets for the treatment of testicular germ cell tumors. Using ATM/Ku70 double-null cell lines, which we generated, we confirmed that ATM-independent ATR activity contributed to persistent phosphorylation of p53(Ser18) in Ku-deficient cells at 12 h post-ionizing radiation. The dose assessment includes image registration, region-of-interest drawing, time-activity curve generation, and manual calculation of residence times followed by dose calculation with the OLINDA/MIRD software.

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The fusion proteins were analyzed by SDS-PAGE and confirmed by analysis with anti-GST and anti-WapA antibodies. Lysis of brucellae by the combined action of glycine and a lysozyme-like agent from rabbit monocytes. Comparative microRNA expression profiles of cynomolgus monkeys, rat, and human reveal that mir-182 is involved in T2D pathogenic processes. In the present study, the effects of chronic exposure on the production of both compounds as well as on the main antioxidant system were compared with those of an acute exposure. Our findings indicate that multicentric lower genital tract disease evolves through different pathways. The role of radiation therapy and chemotherapy in the management of airway tumors other than small-cell carcinoma and non-small-cell carcinoma. A 46-year-old, nonsmoking, nulliparous woman with a 23-year history of rheumatoid arthritis presented with severely destructed right shoulder, right elbow, and right wrist joints, which resulted in a complete loss of working ability. Outcomes of percutaneous and paddle lead implantation for spinal cord stimulation: a comparative analysis of complications, reoperation rates, and health-care costs.

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Over the last 10 years the electrophoretic separation in gels and subsequent visualization of nucleic acids (DNA, RNA) and even genes as well as nucleotides have been much improved, making possible efficient mapping of the genes in humans and all other organisms. Finally, no variation in hepatic mitochondrial and peroxisomal fatty acid oxidation capacity was found in rats fed a high-fat diet for 15, 30 or 60 d. At our institutions, a transcervical approach is chosen when the previous two approach routes are not available. Full k-space was acquired and then downsampled to allow for a measure of truth. An understanding for the abnormal spikes of the EEG simulation in a 2-d neural network. Separation, interaction and properties of clotting components essential for prothrombin activation with special reference to Stuart factor. The formation of C(1)- and C(2)-BSA as well as the C(1)- and C(2)-BA can be linked to structurally corresponding parent contaminants like the xylene isomers and the trimethylbenzene isomers. A mathematical approach to predicting biological values from ruminal pH measurements.

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The aim of this report is to point out the relative toxicity of different commercial products containing lead silicates by studying their in vitro solubility and rate of absorption via the respiratory and digestive systems, compared with those of red lead (lead tetroxide). Disrupting the endogenous rapsyn/calpain interaction enhanced CCh-induced dispersion of AChR clusters. Cryptosporidium parvum has emerged as one of the most important new contaminants found in drinking water. There is no difference of C/EPB beta expression in squamous neoplasia of the cervix. Solvent-equilibrated ion pairs from carbene fragmentation reactions. The purpose of this study was to assess the validity of self-reported history for varicella disease relative to serological evidence of varicella immunity in pregnant women attending antenatal care at clinics located in two diverse geographical locations in the U.S. The degree of cooperation and redundancy between different chaperones is an important problem in understanding how proteins fold in the cell. In this report, we show that dermal Fb inhibit allogeneic T cell activation by autologously derived cutaneous APCs and other stimulators. To our knowledge, it is the first case of synchronous verrucous carcinoma and peripheral T-cell lymphoma. Multiple myeloma is an incurable disease characterized by proliferation of clonal malignant plasma cells (CPCs), which can be immunophenotypically distinguished from polyclonal plasma cells (PPCs) by multiparameter flow cytometry (MFC).

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These antibodies bind to epitopes localized within N-terminally truncated recombinant PrP(90-231). A Teflon patch was glued over the myocardial tear with medical adhesive. Thus, proximity in egocentric space amplifies the valence of social stimuli that, in turn, facilitates emotional memory and approach-avoidance responses. This study aimed to identify predictors of mortality in patients with out-of-hospital cardiac arrest (OHCA) undergoing in-hospital extracorporeal life support system (ECLS) treatment. Expression and function of Ccbe1 in the chick early cardiogenic regions are required for correct heart development. In order to evaluate the tolerability profile of this molecule, a Pharmacovigilance study was undertaken in the Department of Neurology B at the Montpellier University Hospital.

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However, the results of these studies do not directly quantify their effect on the tissues. Responses of the circadian system of rats to conditioned and unconditioned stimuli. Mediastinal chest tube drainage was collected in the intensive care unit for 24 hours. Liquid crystalline elastomers (LCEs) exhibit a number of remarkable physical effects, including the unique, high-stroke reversible mechanical actuation when triggered by external stimuli. Keratinocytes flagyl antibiotic cdc have great promise as targets for gene therapy involving both skin as well as for systemic disorders due to their availability and potential long life span. Simulation results show that MUIP correlation may compromise the assumption of uncorrelated MUAPTs (depending on recruitment level), and MUIP correlation has a downwards spectrum compression effect on the power spectrum of EMG. Only the HPA-5a allele was found among 130 Amerindian chromosomes. We investigated if major depressive disorder (MDD) with concomitant anger attacks was associated with cardiovascular risk factors.

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Under most clinical circumstances, however, ziprasidone may be safely used without ECG monitoring or other special precautions. These heavier and taller children presented with autoantibodies against pancreatic islet tyrosine phosphatases at diagnosis many years later. Drosophila acetylcholinesterase: demonstration of a glycoinositol phospholipid anchor and an endogenous proteolytic cleavage. Both eyes of 101 patients with OSAS and 20 controls were investigated by OCT. Free energy changes of the argininosuccinate synthetase reaction and of the hydrolysis of the inner pyrophosphate bond of adenosine triphosphate.

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The paper describes both the approach and its result and it further expands on the reason behind the few cases of unsatisfactory results. Nicotine (0.5 mg kg(-1) s.c.) did not modify the performance of CB(1) knockout and wild-type mice in this model, whereas scopolamine (0.5 mgkg(-1) i.p.) impaired the performance in both genotypes. The mutated FtmD retained enzymatic activity but did not function under physiological conditions, resulting in blockage of the FTM pathway in A. In this paper we demonstrate that the corresponding herpes simplex virus type 1 replication fork proteins can similarly replace those of HCMV in Vero cells. Experimental results biaxin dose pediatric demonstrate that our automated method outperforms manual process but using only a fraction of the time of the latter. The glomus tumour is a rare benign cutaneous tumour, it is characterized by its clinical and evolutive particular features. The total enzyme activity was also increased (3-fold) in this group of patients.

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