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Romac (Roxithromycin)
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Romac

Romac is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Romac is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Assoral, Azuril, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Dorolid, Elrox, Erybros, Floxid, Infectoroxit, Klomicina, Macrolid, Macrosil, Makrodex, Monobac, Nirox, Overal, Pedrox, Ramivan, Redotrin, Remora, Renicin, Ritosin, Rokilide, Rokithrid, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Romac, Romyk, Roxacine, Roxithromycine, Roxithromycinum, Rulid

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Also known as: Roxithromycin

Description

Romac is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Romac is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Romac is available under several brandnames. Romac is not available in the United States. Romac is available in Australia, Israel and New Zealand. Romac has also been tested to possess antimalarial activity.

Romac prevents bacteria from growing, by interfering with their protein synthesis. Romac binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Romac has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

Dosage

Romac is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.

Overdose

Symptomatic treatment should be provided as required. There is no specific antidote.

Storage

Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Romac or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Romac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Romac if you are allergic to Generic Romac components. Try to be careful with Generic Romac if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Romac taking suddenly.

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Considerably larger quantities of cyanide are required to solubilize gold following the bio-oxidation of gold-bearing ores compared with oxidation by physical-chemical processes. This rejoining of breaks in cells pretreated with UV plus AraC and HU was inhibited by nickel and by arsenite, but not by luminol. The data from this study suggest that long-term conjugated estrogen and depo-medroxyprogesterone acetate treatment have similar effects on lipid and androgen levels except that high-density lipoprotein cholesterol was not significantly increased by depo-medroxyprogesterone acetate. In conclusion, the gait analysis is a promising tool for assessing cerebral ischemia severity, and that it may provide a new means of investigating mechanisms of cerebral ischemia and evaluating potential therapies. However, a standard screening methodology, criteria defining abnormalities, and follow-up procedures remain to be established. This pilot study aimed to investigate whether Lactobacillus casei rhamnosus has the prophylactic efficacy for recurrent cholangitis in comparison with the conventional neomycin prophylaxis. Coaching skills by managers to improve staff performance with residents in LTC facilities can be learned.

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KG-1 cells have a homozygous R229Q amino acid substitution in OGG1 that has been presumed to alter the function of OGG1 and result in elevated levels of genomic 8-oxoG and hypersensitivity to 8-hydroxydeoxyguanosine nucleoside and ionizing radiation observed in KG-1 cells. Both ME-modified C-raf antisense oligos were at least 5-fold more effective than the PS C-raf antisense oligo in blocking C-raf mRNA expression in two cell lines. During a 1-year period, all consecutive patients with cirrhosis who were potential candidates for liver transplantation were screened for extrapyramidal features. Eosinophil proportions in NL fluid increased markedly at 4 and 24h after SICT. Eighty eyes of 80 patients diagnosed with choroidal neovascularization (CNV) caused by AMD were included in the study. Utilization of the greater omentum in treatment of phlegmon of the anterior wall of the stomach. Decrease of excision of LPO-induced DNA damage, epsilonA and 3,N(4)-ethenocytosine (epsilonC) was observed in blood leukocytes of patients developing lung adenocarcinoma, specific histological type of cancer related to inflammation and healing of scars. A case of combined rupture of the uterine tube (in tubular pregnancy), acute appendicitis and hematoma of an ovary with cystic degeneration. Thereafter, the intracellular transport pathways and molecular trafficking machinery have intricate and essential roles in dictating the release and activity of cytokines.

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Microbial experimental evolution as a novel research approach in the Vibrionaceae and squid-Vibrio symbiosis. To estimate the antitumor efficacy of dolastatin-10 in patients with measurable recurrences of platinum-sensitive ovarian carcinoma and to determine the nature and degree of toxicity of dolastatin-10 in these patients. MLST discriminated 40 diploid sequence types (DSTs) among 48 isolates, including 36 novel DSTs, and the XYR1 gene showed the highest discriminatory power. Malaria parasites are frequently transmitted by unscreened blood transfusions in Africa. The aim of this study was to investigate the presence of apparent non-epileptiform activity arising in the same brain area as epileptiform activity in the EEG of paediatric patients with focal epilepsy.

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To test this hypothesis, serial biopsies during porcine liver harvest were obtained immediately upon laparotomy, upon completion of dissection, after 45 and 120 min of cold ischemia, and 60 and 180 min after reperfusion. Vaccines containing this antigen conferred cross strain protection. The dissonance intervention produced significant reductions in outcomes (body dissatisfaction, dieting, negative affect, bulimic symptoms) and the mediator (thin-ideal internalization), change in the mediator correlated with change in outcomes and usually occurred before change in outcomes, and intervention effects became significantly weaker when change in the mediator was partialed, providing support for the hypothesized mediators and this new approach to testing mediation in randomized trials. In 79 subjects with PV, enzyme-linked immunosorbent assays were used to detect IgG autoantibodies reactive with the ectodomain of Dsg1 and Dsg3. Plant defense against pathogens often includes rapid programmed cell death known as the hypersensitive response (HR). This study used the startle probe paradigm to test whether the affect-based defensive motivational system is automatically activated by rejection cues in people who are high in RS. Thus, the pattern of reactivities to each histone component was dependent on the disease, while the intensity was dependent on both the disease and anti-U1RNP antibodies.

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Model discrimination was quantified by calculating the C statistic. A profile of survivors at-risk can be identified that may have application to survivors of more recent holocausts. Medico-legal methodology in the evaluation of bodily injury in common law. Tumor and growth suppression of breast cancer cells by chromosome 17-associated functions. Identification of taxonomic groups corresponding to CSP was ambiguous in some cases when applying solely the genealogical concordance phylogenetic species recognition (GCPSR) concept. A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Primary closure was easy and successful in all cases without widening of the defect and with the umbilicus left intact, because of the total lack of oedema and bowel peel. Tissue factor (TF) is the major initiator of blood coagulation, and a mediator of inflammation, angiogenesis, and carcinogenesis.

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We examined the flora in the anterior nares of 37 patients in the neurologic ward and 36 patients in the medical ward. Calcitriol is also an important determinant of muscle cell proliferation and differentiation, as well as inhibition of apoptosis. Interleukin (IL)-1 beta is a pro-inflammatory cytokine that has been shown to play a pivotal role in the onset of inflammatory bowel disease (IBD), however, the molecular mechanisms underlying the production of IL-1 beta in IBD are not fully understood. Cancer incidence among workers exposed to radon and thoron daughters at a niobium mine. Opioids appear to affect multiple endocrine pathways leading to abnormal levels of different hormones such as testosterone, cortisol, and prolactin (PRL). Most of the structural signs and many behavioural signs of FAS are evident at birth. A study of the characteristics and growth requirements of bovine teat canal in organ culture. The last section discusses emerging surface coating techniques utilizing zwitterionic polymers where ultralow-biofouling surfaces have been demonstrated. Bovine Mastitis Caused By Pasteurella Haemolytica: A Case Report. An education programme of staff was to be undertaken to develop greater awareness of the problem.

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Concentration-effect studies indicate that these proteins are maximally phosphorylated at concentrations of receptor agonists that only slightly elevate cyclic AMP levels. Contributing factors include the barriers encountered in accessing and receiving high-quality health care. from Valle del Cauca, Colombia, are here described and illustrated. The adenoidectomy is the most often made operation in small children but the reasons of adenoid hypertrophy are not completely explained. The present study focused on the marriage status of both men and women with IDDM as well as the number of children of women with IDDM. The average strength of mechanostability is comparable to that of the I27 domain of titin, but the force profiles depend on the pulling direction and anisotropy effects can be substantial.

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Twenty patients with elevated concentrations of blood glucose who were hospitalized in our CCU were studied after randomization noroxin drug to standard care for diabetes or standard care supplemented by use of a CGMS. The recognition of normal emotions and emotions in affective disorders. The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition. In this study, we examined cell viability and gene expression profile in hepatoma cell lines treated with TSA. Evaluating changes in driver behaviour: a risk profiling approach. Serum lipid species and carotenoids were measured, using liquid chromatography electrospray ionization-tandem mass spectrometry and high performance liquid chromatography, as biomarkers of dairy and vegetable intake, respectively. The paper describes and discusses the common psychiatric conditions encountered and referred in general hospitals. Polarotaxis and scototaxis in the supratidal amphipod Platorchestia platensis. A patient with mantle cell lymphoma took 12g/day of ethyl-eicosapentaenoate for 16 months.

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The BB-STAMP method enabled the surgeon to precisely replicate the computer simulation in the real patient with submillimetric accuracy without complexity. Enhanced visuomotor associative learning following stimulation of alpha 2A-adrenoceptors in the ventral prefrontal cortex in monkeys. The GFP (green fluorescent protein)-fused versions of FgFtr1 and FgFtr2 showed normal functions when compared with FgFtr1 and FgFtr2 in an S. Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage. Internuclear distances of inter-metallic compounds are calculated and compared with observed values to show good agreement. Having a single kidney (transplanted IDDM patients) is not associated with accelerated lesion development.

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Matrix metalloproteinases (MMPs) regulate remodeling and degradation of the extracellular matrix. Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism. This male infant was born to a 19-year-old, gravida 1, para 0, woman who received routine prenatal check-up. Magnetic resonance imaging of the spine documented a heterogeneously enhancing dumbbell-shaped extradural lesion causing cord compression at T11/12 level. Effect of induction of anaesthesia with etomidate on corticosteroid synthesis in man.

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A 16-year-old boy developed monocular visual loss due to optic neuropathy following frontal head trauma. In vitro, deep dermal fibroblasts were found higher in the messenger RNA (mRNA) levels of type 1 collagen, alpha smooth muscle actin, transforming growth factor beta, stromal cell-derived factor 1, and tissue inhibitor of metalloproteinase 1, an inhibitor of collagenase (matrix metalloproteinase 1). Neither zymographic assays nor protease assays detected proteolytic activities in either the whole bacteria or conditioned media of E. Incident esophageal cancer cases recorded at the Karachi Cancer Registry for Karachi South, during 1st January 1995 to 31st December 2003 were reviewed. Furthermore, utilizing BIOFIT exercise prescriptions scheduled by an expert system can help users exercise systematically. The role and technique of computed tomography and magnetic resonance imaging in the assessment of the initial injury and analysis of subsequent growth disturbance are discussed.

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