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Rolicytin

Rolicytin is a macrolide antibiotic that fights bacteria in your body. Rolicytin is used to treat many different types of bacterial infections affecting the skin and respiratory system. Rolicytin is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

Other names for this medication:
Binoclar, Biotclarcin, Ciclinil, Clabel, Clacina, Clamycin, Clarimed, Clariston, Claron, Clarosip, Cleanomisin, Hecobac, Kalecin, Kalixocin, Klarifor, Klarimax, Klarithran, Klarithrin, Klonacid, Kofron, Likmoss, Macladin, Macrol, Mononaxy, Nutabact, Preclar

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Also known as: Clarithromycin

Description

Rolicytin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rolicytin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Rolicytin Filmtab and Rolicytin Granules are recommended as the primary agents. Rolicytin Filmtab and Rolicytin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Rolicytin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Rolicytin therapy should continue if clinical response is observed. Rolicytin can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rolicytin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Rolicytin if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Rolicytin if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Rolicytin if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Rolicytin if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Rolicytin usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Rolicytin taking suddenly.

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Employing mutants to study thrombin residues responsible for factor XIII activation peptide recognition: a kinetic study. The aim of the present study was to describe pain intensity, localization, type of sensation and perceived activity limitation in women with different back pain patterns post-partum. The aim of this paper is to propose a nonrigid matching method between the two modalities (CT and MRI). If proven in humans these antigen specific responses may be harnessed for selective immunomodulation of the atherosclerotic plaque. Interestingly, DR3 TG mice, but not wild-type mice, recognized an immunodominant S-Ag epitope between residues 291 and 310 that overlaps with a region of S-Ag recognized by uveitis patients. The data from the RCTs indicates that overall evidence on effectiveness of balneotherapy and spa therapy in LBP is encouraging and reflects the consistency of previous evidence.

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In this report, we determined that the greater wax moth caterpillar Galleria mellonella is a convenient nonmammalian model host for study of the role of the type III secretion system (TTSS) in Pseudomonas aeruginosa pathogenesis. Gadolinium nanoparticle based switchable mirrors: quenching of hydrogenation-dehydrogenation hysteresis. The most recent application is called intensive case management. Nevertheless, the country was able to achieve significant progress in implementing public policies and to take an international leadership position, meeting its constitutional commitment to protect public health. She was found hypertensive having blood pressure 200/110 mm of Hg. In one, defective antigen presentation resulted from the failure of processed nominal antigen and Ia antigen to associate on the antigen presenting cell membrane in a manner sufficient for helper T cell (Th cell) activation. The effect of parental smoking on the lung function of children varies considerably according to geographic area, source of passive smoking, and sex. This chapter attempts to review electrophysiological data that stand at the intersection of two large domains of research: selective attention and semantic processing. There were few significant phenotypic correlations, but all the genetic correlations among ejaculate characters were significantly different from zero. Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase.

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Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins. CINAHL, PsycINFO and Medline databases were searched to retrieve relevant studies of intervention outcomes in children and/or adolescents diagnosed with CFS/ME. Chronic naltrexone treatment increases the heroin-produced facilitation of self-stimulation. In experiments on anaesthetized dogs with coronary artery occlusion the rate of blood flow and dynamics of its changes in the ischemic focus were determined. Therefore, the syntenic array of CRYA-1, 21OH, and BoLA in cattle is different from that observed in rodents, where the genes are closely linked to each other and to GLO1, and consistent with reported linkages in man. The presence of homogeneous immunoglobulins was not correlated with the following clinical parameters: graft-versus-host disease, bacterial sepsis, Epstein-Barr virus or cytomegalovirus infection or invasive fungal infection. Bioinspired formation of 3D hierarchical CoFe2O4 porous microspheres for magnetic-controlled drug release. At least the 1D and 5A eQTLs played important roles in development of freezing tolerance in common wheat. The axial involvement in PsA is associated with a higher cardiovascular risk when compared to non-axial PsA. Proliferative and cytolytic potentials of purified human tumor-infiltrating T lymphocytes.

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The diagnosis was verified by a pathology or definitive radiological report with cross validation from the regional pathology, clinical genetics, cytogenetics and fetal medicine databases. For each structure, both broadband ultrasonic attenuation (BUA) and speed of sound (SOS) were computed. In other neuronal populations studied, colchicine produced neurofilament bundles in the dendrites and a reduction of lysosomes from the soma of neurons. Our results suggest that trabecular bone loss that occurs in adulthood may in part be due to a reduced mechanoresponsiveness in this tissue and/or a reduction in the induced tissue deformation which occurs during habitual loading. Presentation of the Goodpasture autoantigen requires proteolytic unlocking steps that destroy prominent T cell epitopes. On the basis of clinical features and histological findings, as well as findings from the family, the diagnosis of dyskeratosis congenita (DKC) was made. The formation of a protective granuloma involves the orchestrated production of a host of chemokines and cytokines, the upregulation of their receptors along with upregulation of addressins, selectins and integrins to coordinate the recruitment, migration and retention of cells to and within the granuloma. Metallothionein(MT) is a group of conjugated proteins which are rich in cysteine with low molecular weight.

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Here, we exploited the ERAD pathway to induce the degradation of gp160 during viral production, thus leading to the release of gp120-depleted viral particles. The FAMA is a memetic algorithm with a dynamic parameter setting and two local searchers adaptively launched, either one by one or simultaneously, according to the necessities of the evolution. Actual governmental policy is to increase the competition between funds by introducing the possibility to switch from one to the other. Percutaneous metallic stent placement maintains equal palliation in patients with proximal and distal malignant biliary obstructions caused by any tumor type. A genomic library of the yeast Zygosaccharomyces bailii ISA 1307 was constructed in pRS316, a shuttle vector for Saccharomyces cerevisiae and Escherichia coli. Accrual rates for patients age 65 years and older were better than those reported by most other clinical trialists. Thus, Nrf2 is required for timely M phase entry of replicating hepatocytes by ensuring proper regulation of cyclin A2 and the Wee1/Cdc2/cyclin B1 pathway during liver regeneration. Improvements in the prevention of early death from coronary artery disease, along with an aging population, have resulted in an increased prevalence for heart failure in the United States. An Efficient Adaptive Feedback cancellation using by Independent component analysis for hearing aids. Selection of candiidates is crucial so that the most suitable technique can be offered without any delay in initiation of cancer therapy.

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Medium-term results of cryoballoon ablation of the pulmonary veins in patients with paroxysmal and persistent atrial fibrillation. Myelodysplastic syndromes in adults aged less than 50 years: incidence and clinicopathological data. Directing spatial attention to locations within remembered and imagined mental representations. However, we found similar deficits across children with past, current, and future exposure to OHP and, in our preferred model, OHP (past, current, or future placement) had no statistically discernible relation with either reading or math achievement. Association between bone mineralization, body composition, and cardiorespiratory fitness level in young Australian men. The validation strategy is based on the analysis of data acquired during virtual and real burring sessions. In addition to SRH reported in 2000, other covariates included in the mortality models reflected health status, health-related behaviors, and individual resources. However, in Escherichia coli, efficient and gene-specific antisense knock down is possible using antisense peptide nucleic acids (PNAs) attached to carrier peptides (KFFKFFKFFK). This may account for the early disruption of the BBB via up-regulation of p-myosin light chain expression and aggravation of injuries to TJ proteins.

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Collagen induced platelet aggregation: a comparison between several commercially available collagens. We used integrated proteomics and metabolomics approach to investigate the differences between seed coats of M and MM during different stages of seed development (4, 5, and 6 weeks after flowering). However, this may be related to the inconsistencies in study design. The presence of radical cations in their electrochemically oxidized forms is manifested by new bands in the UV-vis-NIR spectra whose appearance can be correlated with reversible redox couples registered in the corresponding cyclic voltammograms at approximately the same potentials as well as with pronounced evolutions of their resonance Raman spectra. BLM increased the frequencies of aneuploidy at 28, 88, and 240 h, and significantly higher frequency of aneuploidy was observed in the cells analyzed at 240 h compared to the cells examined at 28 h.

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Use of a coincidence gamma camera to detect primary tumor with 18fluoro-2-deoxy-glucose in cervical lymph node metastases from an unknown origin. Differential diagnosis of serous meningitis in childhood, with case reports. The medicolegal value of thallium-201 myocardial scintigraphy in assessing the residual damage of closed thoracic injuries. Fluorescence measurement of the kinetics of DNA injection by bacteriophage lambda into liposomes. indicus more than 50 years ago (i.e., Siem Reap), confirmed the occurrence of A. The fluorescent oxidation products of dihydroxyphenylalanine and its esters. Our findings show that the function of TNF receptors I and II is affected by Doxo to ultimately modulate apoptosis and cell survival in H9c2 cardiomyocytes, reinforcing the recent evidence of the relevant role of TNF-alpha receptor-mediated signaling in cardiotoxicity induced by anthracyclines. Soft-tissue reconstruction following debridement for chronic osteomyelitis of the lower limb. Dexamethasone (10 microM) and quinacrine (10 microM) provided protection against the effect of the venom on glomerular filtration rate, urinary flow, percent of sodium tubular transport, percent of proximal tubular sodium transport and perfusion pressure.

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Tamoxifen administration and metabolism in nude mice and nude rats. The blood samples were adjusted by liquid-liquid extraction and indomethacine (and tropesine) was analysed on the reverse phase Separon SGX C-18 with the mobile phase methanol-water (pH 3.2) and detected at 254 nm. Formulated nanoemulsion was evaluated for bactericidal efficacy against Bacillus cereus. In the study, 190 CHS centers were selected from 10 provinces of China via stratified multistage cluster sampling. The core of the device is a long-lived lipid membrane that has been sandwiched between two air-insulated agarose layers which gel in situ. The model omnicef drug revealed formation of a loose granuloma tissue layer between the tendon and bone at 1 week, remodeling starting at 2 weeks, and Sharpey-like collagen fiber formation at 3 and 6 weeks. RNA was obtained from normal human skin tissue and then cDNA was synthesized by RT-PCR. Most states enroll individuals with disabilities who receive Supplemental Security Income (SSI) in Medicaid managed care plans. Immune reconstitution after highly active antiretroviral therapy (HAART) in HIV-infected patients has led to an increase in the number of new CD4 T lymphocytes. Dark-pigmented Bacteroides species in subgingival plaque of adult patients on a rigorous recall program.

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Foraging group size was consistently associated with migratory behavior in both raw species and independent contrast analyses. A representative population (aged 20-65 years) was selected by list-assisted random-digit dialing method from a city with a population of one million. Immunoglobulin (Ig) G, M, C3, and Dirofilaria antigen deposits were observed in a segmental granular pattern. Seven-year follow-up of patients diagnosed with atypical odontalgia: a prospective study. The results of magnitude detecting also provide us with useful information. The experiments with splenectomized rats treated with vincristine and colchicine were performed and statistically significant increases in MN-PCE were found with 0.05, 0.1, 0.15 mg/kg of vincristine and 0.7 and 1 mg/kg of colchicine. (4) Echo/Doppler may disclose alternative abnormalities explaining symptoms found in a patient with suspected pulmonary embolism such as pericardial disease, myocardial infarction, aortic dissection, hypovolemic shock, etc. Data from the Israeli Draft Board Register of intelligence, social functioning and behaviour testing for all Israeli males aged 16-17 was linked with data from the National Psychiatric Hospitalisation Case Register. We measured TgCDPK4 activity, induced by calcium influx, using a kinase assay.

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Nonuniform light distribution is a fundamental limitation to biological hydrogen production by phototrophic bacteria. After 2 years of follow up similar outcomes (MACE, all-cause mortality/MI, TLR) were observed in real-world diabetic patients, including those with complex lesions and patient characteristics, treated with R-ZES and EES. We have monitored the modifications of the Hg supported monolayer caused by ILs using rapid cyclic voltammetry (RCV), alternating current voltammetry (ACV), and electrochemical impedance spectroscopy (EIS). As a result, the permanent sticking of large clusters required the formation of a large number of connections, whereas that of small clusters might be realized even with a small number of connections. Therefore S100B may serve as a potential adjunct treatment to promote neuroregeneration following brain damage. Health care providers can draw on the knowledge about the impact of beliefs about ageing to help them reach shared decisions with older patients about the use of walking aids. We identified a novel Kir6.2 mutation (I167L) causing DEND syndrome.

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