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Rolicytin (Clarithromycin)

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Rolicytin is a macrolide antibiotic that fights bacteria in your body. Rolicytin is used to treat many different types of bacterial infections affecting the skin and respiratory system. Rolicytin is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

Other names for this medication:
Binoclar, Biotclarcin, Ciclinil, Clabel, Clacina, Clamycin, Clarimed, Clariston, Claron, Clarosip, Cleanomisin, Hecobac, Kalecin, Kalixocin, Klarifor, Klarimax, Klarithran, Klarithrin, Klonacid, Kofron, Likmoss, Macladin, Macrol, Mononaxy, Nutabact, Preclar

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Also known as: Clarithromycin


Rolicytin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rolicytin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Rolicytin Filmtab and Rolicytin Granules are recommended as the primary agents. Rolicytin Filmtab and Rolicytin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Rolicytin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Rolicytin therapy should continue if clinical response is observed. Rolicytin can be discontinued when the patient is considered at low risk of disseminated infection.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rolicytin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Rolicytin if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Rolicytin if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Rolicytin if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Rolicytin if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Rolicytin usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Rolicytin taking suddenly.

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Diffusion measurements at long observation times in the presence of spatially variable internal magnetic field gradients. We find that the Lorentz-force back-action can be so large that, in combination with complex nonlinear Josephson dynamics, it generates intrinsic self-sustained oscillations. The broad functional group tolerance of the cycloaddition reaction and further palladium-catalyzed cross-coupling reactions allowed the preparation of polyfunctionalized 1,4,5-pyrazoles that are otherwise difficult to obtain by conventional methods. Localization of bone morphogenetic protein-induced bone and cartilage formation on a new carrier: fibrous collagen membrane. About a double-body immersion horn system to be used for quantitative sonochemical studies. A community-based cohort study of schoolchildren (aged 6 to 14 years), the Orinda (Calif) Longitudinal Study of Myopia.

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Employing mutants to study thrombin residues responsible for factor XIII activation peptide recognition: a kinetic study. The aim of the present study was to describe pain intensity, localization, type of sensation and perceived activity limitation in women with different back pain patterns post-partum. The aim of this paper is to propose a nonrigid matching method between the two modalities (CT and MRI). If proven in humans these antigen specific responses may be harnessed for selective immunomodulation of the atherosclerotic plaque. Interestingly, DR3 TG mice, but not wild-type mice, recognized an immunodominant S-Ag epitope between residues 291 and 310 that overlaps with a region of S-Ag recognized by uveitis patients. The data from the RCTs indicates that overall evidence on effectiveness of balneotherapy and spa therapy in LBP is encouraging and reflects the consistency of previous evidence.

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Also, the rate of decolorization reaction showed a significant increase with increasing the amount of the catalyst and temperature. Once this has been achieved, the place of clinically active anti-angiogenic agents will need to be further refined in order to determine where they best fit in our current armamentarium, either as single agents or in combination with classical anticancer therapies. EMG and biopsy abnormalities mimicking myopathy may often be found in patients with LEMS. U937 cells can utilize plasminogen activator to regulate human interferon-gamma. Tracheostomy as a method of prevention of acute respiratory insufficiency. BOX-PCR analysis revealed a large genetic diversity among clinical strains and we did not find a predominant clone with the ability to persist in a hospital environment. To investigate the role of alpha7beta1 integrin in sensory axon regeneration, dorsal root ganglia of adult mice were cultured in gels of laminin-rich extracellular matrix (Matrigel) or collagen. Here we report a simple and fast method for wine fingerprinting based on direct matrix-assisted laser desorption/ionization (MALDI) mass spectrometry analysis of different red wine samples, useful for batch-to-batch analysis and for the detection of key compounds even in trace amounts which may vary from vintage to vintage, and from one treatment to another one.

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In this report, we determined that the greater wax moth caterpillar Galleria mellonella is a convenient nonmammalian model host for study of the role of the type III secretion system (TTSS) in Pseudomonas aeruginosa pathogenesis. Gadolinium nanoparticle based switchable mirrors: quenching of hydrogenation-dehydrogenation hysteresis. The most recent application is called intensive case management. Nevertheless, the country was able to achieve significant progress in implementing public policies and to take an international leadership position, meeting its constitutional commitment to protect public health. She was found hypertensive having blood pressure 200/110 mm of Hg. In one, defective antigen presentation resulted from the failure of processed nominal antigen and Ia antigen to associate on the antigen presenting cell membrane in a manner sufficient for helper T cell (Th cell) activation. The effect of parental smoking on the lung function of children varies considerably according to geographic area, source of passive smoking, and sex. This chapter attempts to review electrophysiological data that stand at the intersection of two large domains of research: selective attention and semantic processing. There were few significant phenotypic correlations, but all the genetic correlations among ejaculate characters were significantly different from zero. Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase.

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Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins. CINAHL, PsycINFO and Medline databases were searched to retrieve relevant studies of intervention outcomes in children and/or adolescents diagnosed with CFS/ME. Chronic naltrexone treatment increases the heroin-produced facilitation of self-stimulation. In experiments on anaesthetized dogs with coronary artery occlusion the rate of blood flow and dynamics of its changes in the ischemic focus were determined. Therefore, the syntenic array of CRYA-1, 21OH, and BoLA in cattle is different from that observed in rodents, where the genes are closely linked to each other and to GLO1, and consistent with reported linkages in man. The presence of homogeneous immunoglobulins was not correlated with the following clinical parameters: graft-versus-host disease, bacterial sepsis, Epstein-Barr virus or cytomegalovirus infection or invasive fungal infection. Bioinspired formation of 3D hierarchical CoFe2O4 porous microspheres for magnetic-controlled drug release. At least the 1D and 5A eQTLs played important roles in development of freezing tolerance in common wheat. The axial involvement in PsA is associated with a higher cardiovascular risk when compared to non-axial PsA. Proliferative and cytolytic potentials of purified human tumor-infiltrating T lymphocytes.

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This study provides the first evidence that the primary electrophysiological activity of multiple individual neurons to ischemic stroke is reduced in the lesion boundary and/or stopped in and adjacent to the lesion core. The mortality of rasH2-Tg mice during the study period was very low, the same as for the non-Tg mice. CAPE treatment increased the nuclear translocation of XIAP, indicating increased apoptosis in melanoma cells. We found that 2-arachidonoylglycerol induces the migration of differentiated HL-60 cells. Recent studies have demonstrated that neurotrophins may also induce cell death via the p75 receptor. Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research.

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The diagnosis was verified by a pathology or definitive radiological report with cross validation from the regional pathology, clinical genetics, cytogenetics and fetal medicine databases. For each structure, both broadband ultrasonic attenuation (BUA) and speed of sound (SOS) were computed. In other neuronal populations studied, colchicine produced neurofilament bundles in the dendrites and a reduction of lysosomes from the soma of neurons. Our results suggest that trabecular bone loss that occurs in adulthood may in part be due to a reduced mechanoresponsiveness in this tissue and/or a reduction in the induced tissue deformation which occurs during habitual loading. Presentation of the Goodpasture autoantigen requires proteolytic unlocking steps that destroy prominent T cell epitopes. On the basis of clinical features and histological findings, as well as findings from the family, the diagnosis of dyskeratosis congenita (DKC) was made. The formation of a protective granuloma involves the orchestrated production of a host of chemokines and cytokines, the upregulation of their receptors along with upregulation of addressins, selectins and integrins to coordinate the recruitment, migration and retention of cells to and within the granuloma. Metallothionein(MT) is a group of conjugated proteins which are rich in cysteine with low molecular weight.

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Here, we exploited the ERAD pathway to induce the degradation of gp160 during viral production, thus leading to the release of gp120-depleted viral particles. The FAMA is a memetic algorithm with a dynamic parameter setting and two local searchers adaptively launched, either one by one or simultaneously, according to the necessities of the evolution. Actual governmental policy is to increase the competition between funds by introducing the possibility to switch from one to the other. Percutaneous metallic stent placement maintains equal palliation in patients with proximal and distal malignant biliary obstructions caused by any tumor type. A genomic library of the yeast Zygosaccharomyces bailii ISA 1307 was constructed in pRS316, a shuttle vector for Saccharomyces cerevisiae and Escherichia coli. Accrual rates for patients age 65 years and older were better than those reported by most other clinical trialists. Thus, Nrf2 is required for timely M phase entry of replicating hepatocytes by ensuring proper regulation of cyclin A2 and the Wee1/Cdc2/cyclin B1 pathway during liver regeneration. Improvements in the prevention of early death from coronary artery disease, along with an aging population, have resulted in an increased prevalence for heart failure in the United States. An Efficient Adaptive Feedback cancellation using by Independent component analysis for hearing aids. Selection of candiidates is crucial so that the most suitable technique can be offered without any delay in initiation of cancer therapy.

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Medium-term results of cryoballoon ablation of the pulmonary veins in patients with paroxysmal and persistent atrial fibrillation. Myelodysplastic syndromes in adults aged less than 50 years: incidence and clinicopathological data. Directing spatial attention to locations within remembered and imagined mental representations. However, we found similar deficits across children with past, current, and future exposure to OHP and, in our preferred model, OHP (past, current, or future placement) had no statistically discernible relation with either reading or math achievement. Association between bone mineralization, body composition, and cardiorespiratory fitness level in young Australian men. The validation strategy is based on the analysis of data acquired during virtual and real burring sessions. In addition to SRH reported in 2000, other covariates included in the mortality models reflected health status, health-related behaviors, and individual resources. However, in Escherichia coli, efficient and gene-specific antisense knock down is possible using antisense peptide nucleic acids (PNAs) attached to carrier peptides (KFFKFFKFFK). This may account for the early disruption of the BBB via up-regulation of p-myosin light chain expression and aggravation of injuries to TJ proteins.

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Collagen induced platelet aggregation: a comparison between several commercially available collagens. We used integrated proteomics and metabolomics approach to investigate the differences between seed coats of M and MM during different stages of seed development (4, 5, and 6 weeks after flowering). However, this may be related to the inconsistencies in study design. The presence of radical cations in their electrochemically oxidized forms is manifested by new bands in the UV-vis-NIR spectra whose appearance can be correlated with reversible redox couples registered in the corresponding cyclic voltammograms at approximately the same potentials as well as with pronounced evolutions of their resonance Raman spectra. BLM increased the frequencies of aneuploidy at 28, 88, and 240 h, and significantly higher frequency of aneuploidy was observed in the cells analyzed at 240 h compared to the cells examined at 28 h.

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Kaplan-Meier analysis was performed, and the log-rank test via SPSS v.22 was used for estimating significance levels. Effect of gamma irradiation on microbial load and sensory characteristics of aniseed (Pimpinella anisum). Long-term survey of heavy-metal pollution, biofilm contamination and diatom community structure in the Riou Mort watershed, South-West France. In addition, we observed the relationship between prognosis and modulation of E-cadherin by HGF in hypopharyngeal carcinoma. Mitochondrial genome of the Trans-Andean shovelnose catfish Sorubim cuspicaudus (Siluriformes, Pimelodidae). Cyclo-oxygenase mediated prostaglandins are important determinants of glomerular development and kidney function. Dermal leukocytes were obtained from fluid aspirated from epidermal suction blisters raised over secondary syphilis skin lesions. A comparison of the human map to the orthologous region on mouse chromosome 11 revealed significant differences in the number and arrangement of genes, indicating that many chromosomal breaks with partial duplications, inversions, and deletions occurred predominantly in the primate lineage. Uterine MMT tumors according to WHO diagnostic criteria are not rare. The advantage of psychophysiological stress assessment and screening of health risk in PKMs is that results indicate the mechanisms of the effects of stress on cognitive function and health status.

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Use of a coincidence gamma camera to detect primary tumor with 18fluoro-2-deoxy-glucose in cervical lymph node metastases from an unknown origin. Differential diagnosis of serous meningitis in childhood, with case reports. The medicolegal value of thallium-201 myocardial scintigraphy in assessing the residual damage of closed thoracic injuries. Fluorescence measurement of the kinetics of DNA injection by bacteriophage lambda into liposomes. indicus more than 50 years ago (i.e., Siem Reap), confirmed the occurrence of A. The fluorescent oxidation products of dihydroxyphenylalanine and its esters. Our findings show that the function of TNF receptors I and II is affected by Doxo to ultimately modulate apoptosis and cell survival in H9c2 cardiomyocytes, reinforcing the recent evidence of the relevant role of TNF-alpha receptor-mediated signaling in cardiotoxicity induced by anthracyclines. Soft-tissue reconstruction following debridement for chronic osteomyelitis of the lower limb. Dexamethasone (10 microM) and quinacrine (10 microM) provided protection against the effect of the venom on glomerular filtration rate, urinary flow, percent of sodium tubular transport, percent of proximal tubular sodium transport and perfusion pressure.

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Increase in emulsification time resulted in decrease in droplet diameter. Efficacy of hypnosis in adults undergoing surgery or medical procedures: a meta-analysis of randomized controlled trials. Biogeographical distribution and diversity of bacterial communities in surface sediments of the South China Sea. Hence, the identification of a useful source of cardiomyocyte progenitors is of great interest for possible use in regenerative therapy. Physicians and medicine in early Alachua County and Gainesville, Florida. The prevalence of epilepsy, coronary heart disease and alcohol abuse among these diagnostic subgroups. Various markers have shown promise as diagnostic markers and prognostic predictors in malignant mesothelioma (MM). The authors speculated that it could play an important permissive role in myocyte realignment, thereby resulting in the changes in cardiac amoxil liquid dosage size and shape.

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Reduction of the glucose residue of Neu5-Ac alpha 2-6Gal beta 1-4Glc diminishes the interaction, while truncation of the sialic acid side chain by mild periodate oxidation abolishes it. The improved resolution obtained from acrylamide gels and the superior binding properties of the nylon membranes have allowed us to accurately map 74 distinct oxolinic acid-induced cleavage sites within pBR322. Due to the abundance and importance of muscarinic receptors, the presence of a cholinergic substance in soy could have numerous implications. Performance of PCR-restriction fragment length polymorphism analysis of the Helicobacter pylori ureB gene in differentiating gene variants. A retrospective administrative claims data analysis that used medical and pharmacy claims data and enrollment information from a large, national U.S. The endoplasmic reticulum HSP70 chaperone BiP/Kar2p is both the sensor for the unfolded protein response (UPR) in the yeast Saccharomyces cerevisiae and a target of transcriptional up-regulation by this signaling pathway. In the documentary Boston Med, patients, their family members, and their careproviders agree to be filmed in real medical situations. Along with the weight loss, resolution of MS and a significant shift towards decrease in the number of MS components was observed. A general mathematical proof of a formula proposed and used by Fan et al. The main problem is that they fail to adequately consider the lateral transport of radiation or loss of electronic equilibrium near interface between two heterogeneous mediums.

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Compared with controls, FASD children had elongated reaction times, excessive direction errors, and no express saccades. Tumor necrosis factor-alpha (TNF-alpha) plays a central role in the pathogenesis of acute pancreatitis and related systemic complications. Ten fragment lengths were observed by denaturing polyacrylamide gel electrophoresis on an automatic DNA sequencer resulting in 21 unique fragment patterns. The technique employed is described in detail and the indications and controversies surrounding such an approach are discussed. Although the involvement have to wait after taking flagyl to drink alcohol of lung cell apoptosis in each of these examples seems clear, the many factors comprising the normal and abnormal regulation of cell death remain to be elucidated and are likely to be different in each situation. Septins represent a family of phylogenetically conserved proteins required for cytokinesis. Deconjugation by sulphate transfer and intestinal absorption of troglitazone sulphate (M1), the major metabolite of a thiazolidinedione antidiabetic drug, troglitazone, were studied in the male F344 rat using 14C-troglitazone, 4C-M1 and 35S-M1. Changes in the method of determination or reference study group have led to different results. Burden of diseases attributable to low physical activity is increasing worldwide mainly among working age populations.

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We conclude that prostatic carcinoma may cause SIADH and should therefore be considered in the differential diagnosis. Filtering of drinking water to remove the copepod intermediate hosts of Dracunculus medinensis is a primary strategy for control of guinea-worm disease. Design and application of a rapid screening technique for isolation of selenite reduction-deficient mutants of Shewanella putrefaciens. In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin. HIV-infected individuals starting combination ART with a low likelihood of previous antiretroviral exposure. Serum PTH was determined in 170 male HD patients by either a Bio-intact PTH (Bio-PTH) or I-PTH assay. Treatment is also controversial regarding the use of anti-inflammatory zithromax dose pneumonia or immunosuppressive therapy. Attending physicians (for 1988-89 only), program supervisors (program directors and chief residents), and nurses (for 1988-89 only) rated the same residents, and these ratings were compared with those of the patients. There is controversy about depression being a physical illness, in part because a reproducible, sensitive, and specific biologic marker is not available. Our data indicate the potential of miR-9 as a novel prognostic biomarker for HCC.

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Foraging group size was consistently associated with migratory behavior in both raw species and independent contrast analyses. A representative population (aged 20-65 years) was selected by list-assisted random-digit dialing method from a city with a population of one million. Immunoglobulin (Ig) G, M, C3, and Dirofilaria antigen deposits were observed in a segmental granular pattern. Seven-year follow-up of patients diagnosed with atypical odontalgia: a prospective study. The results of magnitude detecting also provide us with useful information. The experiments with splenectomized rats treated with vincristine and colchicine were performed and statistically significant increases in MN-PCE were found with 0.05, 0.1, 0.15 mg/kg of vincristine and 0.7 and 1 mg/kg of colchicine. (4) Echo/Doppler may disclose alternative abnormalities explaining symptoms found in a patient with suspected pulmonary embolism such as pericardial disease, myocardial infarction, aortic dissection, hypovolemic shock, etc. Data from the Israeli Draft Board Register of intelligence, social functioning and behaviour testing for all Israeli males aged 16-17 was linked with data from the National Psychiatric Hospitalisation Case Register. We measured TgCDPK4 activity, induced by calcium influx, using a kinase assay.

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Nonuniform light distribution is a fundamental limitation to biological hydrogen production by phototrophic bacteria. After 2 years of follow up similar outcomes (MACE, all-cause mortality/MI, TLR) were observed in real-world diabetic patients, including those with complex lesions and patient characteristics, treated with R-ZES and EES. We have monitored the modifications of the Hg supported monolayer caused by ILs using rapid cyclic voltammetry (RCV), alternating current voltammetry (ACV), and electrochemical impedance spectroscopy (EIS). As a result, the permanent sticking of large clusters required the formation of a large number of connections, whereas that of small clusters might be realized even with a small number of connections. Therefore S100B may serve as a potential adjunct treatment to promote neuroregeneration following brain damage. Health care providers can draw on the knowledge about the impact of beliefs about ageing to help them reach shared decisions with older patients about the use of walking aids. We identified a novel Kir6.2 mutation (I167L) causing DEND syndrome.

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