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Riazole (Metronidazole)

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Riazole is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Acuzole, Amodis, Amotein, Anaeromet, Anazol, Arilin, Corsagyl, Dazotron, Etronil, Flagystatine, Flazol, Flazole, Gnostol, Gynomix, Metco, Metrobac, Metrolag, Metronex, Metronidazol, Metronidazole, Metrosept, Metrozin, Metrozol, Mtrocol, Nidazol, Rhodogil, Rozagel, Trichomonacid, Vagilen, Venogyl, Wingyl

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Cleocin, Flagyl, Amoxil, Vantin, Suprax, Terramycin

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Also known as: Metronidazole


Riazole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Riazole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


In the Female. One-day treatment – two grams of Riazole, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


Single oral doses of Riazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Riazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Riazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Riazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Metronidazole should be used with caution in patients with active disease of the Central Nervous System. The treatment should be withdrawn in case of ataxia, dizziness, or confusion. The risk of aggravation of the neurological state should be considered in patients suffering from severe central and peripheral neurological diseases, fixed or progressive paraesthesia and epilepsy. Caution is required in patients with active disease of the central nervous system except for brain abscess.

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Structure of the physical therapy benefit in a typical Blue Cross Blue Shield preferred provider organization plan available in the individual insurance market in 2011. A comparative study into the one year cumulative incidence of depression after stroke and myocardial infarction. Pharmacokinetic, toxicological and morphopathological considerations on some Rumanian psychotropic drugs. The complete apical seal without percolation and transit of bacteria and their products along the wall of the cleocin 1% gel endodontic canal is the fundamental condition to obtain a lasting result of a correct endodontic therapy. Contaminated particles clearly have toxic potency, not only because they are a continuous source of dissolved xenobiotics, but also because the particle bound fraction can become available within the body of particle feeding organisms. Here, we report the systematic comparison of fly models of two polyglutamine (polyQ) diseases. The management and treatment of the cardiovascular complications condition the vital prognosis. Scintigraphic study on the distribution of radiolabeled cis-diamminedichloroplatinum (II) in the tumor-bearing rabbit: a comparison between intra-arterial injection with lipiodol and intravenous injection. Resilience and post-traumatic stress disorder in the acute aftermath of rape: a comparative analysis of adolescents versus adults. The power of the method is increased if the QTL effects conditioned by inter-population origin and inbreeding are enhanced.

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