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Penalox (Azithromycin)

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Penalox is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
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Also known as: Azithromycin


Penalox is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Penalox inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Penalox is the local analog (generic) of more famous drug Penalox that has the same active substance (ingredient) and in result the same therapeutic effect. The main difference is that Penalox is registered by a small local pharmaceutical company. The presence of the same active substance guarantees an identical pharmaceutical (therapeutic) effect on the body.

It is possible to buy Penalox only in the pharmacies of the country where it is produced. With us, you can buy its more famous analog Penalox, which is approved by the FDA and is sold worldwide. The same active substance guarantees the identity of the drugs and the identity of the pharmaceutical properties (they have only different names and packaging, in which they are sold).


Dosage of Penalox is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.


If you overdose Penalox and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Penalox overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.


Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Penalox Tablet.

Side effects

The most common side effects associated with Penalox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death. Discontinue Penalox immediately if signs and symptoms of hepatitis occur.

The presence of other medical problems may affect the use of Penalox. Make sure you tell your doctor if you have any other medical problems, especially: allergy to any macrolide and ketolide antibiotic or liver disease with prior Penalox use or bacteremia (blood infection) or cystic fibrosis or infections, nosocomial or hospital-acquired or weak immune system or bradycardia (slow heartbeat) or hypokalemia (low potassium in the blood) or hypomagnesemia (low magnesium in the blood)

Not recommended in patients with these conditions: congestive heart failure or diarrhea or heart disease or Heart rhythm problems (e.g., prolonged QT interval), history of or Myasthenia gravis (severe muscle weakness).

Use with caution. May make these conditions worse: kidney disease, severe or liver disease. The effects may be increased because of slower removal of the medicine from the body.

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