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Onexid (Clarithromycin)
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Onexid

Onexid belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection.

Other names for this medication:
Abbotic, Biclar, Clacee, Clacine, Clarimac, Clarimax, Claritrox, Clarocin, Claron, Clarosip, Clasine, Cleron, Euromicina, Klabax, Klarifor, Klarithran, Klerimed, Kofron, Mononaxy, Monozeclar, Onexid, Preclar, Quedox, Rocin, Rodizim, Synclar

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Biaxin, Flagyl, Omnicef, Cipro, Cleocin, Chloromycetin

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Also known as: Clarithromycin

Description

Onexid is used to treat many different types of bacterial infections affecting the skin and respiratory system. Onexid is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori. Onexid fights bacteria in the body. Onexid is also known as Clarithromycin, Maclar, Klaricid, Klacid, Clarimac, Claribid.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Onexid Filmtab and Onexid Granules are recommended as the primary agents. Onexid Filmtab and Onexid Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Onexid is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Onexid therapy should continue if clinical response is observed. Onexid can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Onexid XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Onexid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Discontinue immediately if hepatitis or severe hypersensitivity reactions occurs. Severe renal impairment. Proarrhythmic conditions (eg, hypokalemia, hypomagnesemia, bradycardia); avoid. Myasthenia gravis. History of porphyria; avoid concomitant ranitidine bismuth citrate. Elderly. Pregnancy (Cat.C): usually not recommended. Nursing mothers.

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