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Nofocin (Norfloxacin)
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Nofocin

Nofocin is a fluoroquinolone antibiotic medicine used in adults to treat certain infections caused by certain germs called bacteria. It is not known if Nofocin is safe and works in children under 18 years of age. Children have a higher chance of getting bone and joint (musculoskeletal) problems while taking Nofocin.

Other names for this medication:
Barazan, Baxicin, Chibroxine, Flobarl, Lexiflox, Noflo, Nofloxan, Nofocin, Nolicin, Norflodal, Norflomax, Norocin, Nufloxib, Quinabic, Respexil, Ritromine, Senro, Setanol, Sinobid, Stbanil, Theanorf, Uritracin, Uroflox, Uroseptal, Uticina, Xaflor, Xasmun

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Biaxin, Rulide, Keflex, Amoxil, Vantin, Ilosone

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Also known as: Norfloxacin

Description

Nofocin comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Nofocin. Take Nofocin at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Nofocin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Nofocin at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Nofocin. If your symptoms do not improve or if they get worse, call your doctor.

Take Nofocin until you finish the prescription, even if you feel better. Do not stop taking Nofocin without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Nofocin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Nofocin is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

Before taking Nofocin tell your doctor and pharmacist if you are allergic or have had a severe reaction to Nofocin; other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the U.S.), moxifloxacin (Avelox), nalidixic acid (NegGram), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.), or any other medications.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, herbal products, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); caffeine or medications that contain caffeine (Excedrin, NoDoz, Vivarin, others); cisapride (Propulsid) (not available in the U.S.); clozapine (Clozaril, Fazaclo); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); erythromycin (E.E.S, E-Mycin, Erythrocin, others); glyburide (DiaBeta, in Glucovance, Micronase, others); certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nitrofurantoin (Furadantin, Macrobid, Macrodantin); probenecid (in Col-Probenecid, Probalan); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); ropinirole (Requip); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Uniphyl, others); and tizanidine (Zanaflex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

If you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others), didanosine (Videx) sucralfate (Carafate), or supplements or multivitamins that contain iron or zinc, take these medications 2 hours before or 2 hours after you take Nofocin.

Tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting or sudden death) or an irregular heartbeat and if you have or have ever had nerve problems, a low level of potassium in your blood, a slow heartbeat, chest pain, seizures, myasthenia gravis (condition that causes weakness of certain muscles), cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke), or glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disorder).

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Nofocin, call your doctor.

You should know that this medication may cause dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness and coordination until you know how Nofocin affects you.

Plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Nofocin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.

Overdose

If you overdose Generic Nofocin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Nofocin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Nofocin if you are allergic to Generic Nofocin components or to quinolone antibiotics such as ciprofloxacin, gatifloxacin, gemifloxacin, levofloxacin, lomefloxacin, moxifloxacin or ofloxacin. Generic Nofocin should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections. Be careful if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful if you have seizures, brain disorders (e.g., cerebral arteriosclerosis, tumor, increased intracranial pressure), muscle disease/weakness (e.g., myasthenia gravis), heart problems (e.g., cardiomyopathy, slow heart rate, torsades de pointes, QTc interval prolongation), kidney disease, mineral imbalance (e.g., low potassium or magnesium), history of tendonitis/tendon problems. When you take Generic Nofocin you should drink plenty of fluids. Avoid alcohol and beverages containing caffeine (coffee, tea, colas), do not eat large amounts of chocolate. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. It can be dangerous to stop Generic Nofocin taking suddenly.

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From E2g to other modes: effects of pressure on electron-phonon interaction in MgB2. Scientific and review articles, book chapters, and clinical practice. Determining the outcome of field-based competition between two Rhizopogon species using real-time PCR. Attenuated Salmonella enterica serovar Typhi and Shigella flexneri 2a strains mucosally deliver DNA vaccines encoding measles virus hemagglutinin, inducing specific immune responses and protection in cotton rats. We utilize a TrkA(taulacZ) mouse line to label the trajectories of all TrkA-positive peripheral axons in the intact mouse embryo. Current attempts to engineer the genetic code are reviewed with reference to theoretical works on its natural history. Curiously, only one inter/intrarater reproducibility study is available and it uses a cutoff level of 6, rather than the Beighton-recommended 4 positive tests. Sexual maturation was associated with significant increase in the expression of Bcl-2, Bax, PKA, CREB-1 and TK and with decrease in the expression of ERK1,2 related MAPK, cyclin B1 and PKG in granulosa cells. Transfer rates up to 61.04 bits/min were achieved (mean 17.64 bits/min) for this situation indicating an encouraging generalization performance.

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Elevated serum levels of neopterin and soluble interleukin-2 receptor in patients with ovarian cancer. Electronic connection between the quinone and cytochrome C redox pools and its role in regulation of mitochondrial electron transport and redox signaling. Arg133Cys mutation of Notch3 in two unrelated Japanese families with CADASIL. Gum chewing is a safe and simple treatment to reduce POI, and is associated with a reduction in systemic inflammatory markers and complications. Surgical repair is the definitive treatment and involves primary or mesh repair of the defect as appropriate. My original report to Hughes on the content of this document is reproduced here.

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Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas. Oral administration of surfactant protein-a reduces pathology in an experimental model of necrotizing enterocolitis. Experimental identification of phosphorylation sites is labour-intensive and often limited by the availability and optimisation of enzymatic reaction. So, we examined 13 patients with biliary leak after liver transplantation, attempting to evaluate the role of endoscopic diagnosis and treatment of biliary leak and the incidence of bile duct stricture after healing of the leak. The protracted course of ARN in this patient also suggests that the dysregulation of the immune system has probably existed for a long time.

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