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Nizole (Metronidazole)
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Nizole

Nizole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Aldezol, Anegyn, Anerozol, Efloran, Filmet, Florazole, Gnostol, Gynotran, Imizine, Litagyl, Medazol, Metrocev, Metrolyl, Metropast, Metrovax, Metrozin, Metsina, Nidazyl, Robaz, Rovamet, Rupezol, Servizol, Trikozol, Vagimid, Varizil, Zyomet

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Sumycin, Avelox, Chloromycetin, Ilosone, Cefixime

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Also known as: Metronidazole

Description

Nizole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Nizole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

In elderly patients, the pharmacokinetics of metro- nidazole may be altered, and, therefore, monitor- ing of serum levels may be necessary to adjust the metronidazole dosage accordingly.

Overdose

Single oral doses of Nizole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Nizole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Nizole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store Nizole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nizole out of the reach of children and away from pets.

Side effects

The most common side effects associated with Nizole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Nizole Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Nizole Tablets is contraindicated during the first trimester of pregnancy.

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