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Microxin (Norfloxacin)
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Microxin

Microxin is a fluoroquinolone antibiotic medicine used in adults to treat certain infections caused by certain germs called bacteria. It is not known if Microxin is safe and works in children under 18 years of age. Children have a higher chance of getting bone and joint (musculoskeletal) problems while taking Microxin.

Other names for this medication:
Ambigram, Apiflox, Baccidal, Bacteriotal, Barazan, Biscolet, Chibroxin, Chibroxol, Constilax, Effectsal, Esclebin, Floxatral, Floxen, Foxgoria, Lemorcan, Lorcamin, Mariotton, Mitatonin, Nofloxan, Nolicin, Noprose, Norcozine, Norflogen, Norflohexal, Normax, Noroxine, Notler, Noxacin, Ovinol, Parcetin, Pistofil, Setanol, Shinun, Trizolin, Unasera, Uricin, Uronovag, Urotem, Vefloxa, Xaflor

Similar Products:
Zithromax, Cleocin, Myambutol, Terramycin, Levaquin, Cipro, Avelox, Ceftin, Chloromycetin

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Also known as: Norfloxacin

Description

Microxin comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Microxin. Take Microxin at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Microxin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Microxin at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Microxin. If your symptoms do not improve or if they get worse, call your doctor.

Take Microxin until you finish the prescription, even if you feel better. Do not stop taking Microxin without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Microxin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Microxin is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

Before taking Microxin tell your doctor and pharmacist if you are allergic or have had a severe reaction to Microxin; other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the U.S.), moxifloxacin (Avelox), nalidixic acid (NegGram), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.), or any other medications.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, herbal products, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); caffeine or medications that contain caffeine (Excedrin, NoDoz, Vivarin, others); cisapride (Propulsid) (not available in the U.S.); clozapine (Clozaril, Fazaclo); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); erythromycin (E.E.S, E-Mycin, Erythrocin, others); glyburide (DiaBeta, in Glucovance, Micronase, others); certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nitrofurantoin (Furadantin, Macrobid, Macrodantin); probenecid (in Col-Probenecid, Probalan); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); ropinirole (Requip); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Uniphyl, others); and tizanidine (Zanaflex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

If you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others), didanosine (Videx) sucralfate (Carafate), or supplements or multivitamins that contain iron or zinc, take these medications 2 hours before or 2 hours after you take Microxin.

Tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting or sudden death) or an irregular heartbeat and if you have or have ever had nerve problems, a low level of potassium in your blood, a slow heartbeat, chest pain, seizures, myasthenia gravis (condition that causes weakness of certain muscles), cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke), or glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disorder).

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Microxin, call your doctor.

You should know that this medication may cause dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness and coordination until you know how Microxin affects you.

Plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Microxin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.

Overdose

If you overdose Generic Microxin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Microxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Taking norfloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward. These problems may affect tendons in your shoulder, your hand, the back of your ankle, or in other parts of your body. Tendinitis or tendon rupture may happen to people of any age, but the risk is highest in people over 60 years of age. Tell your doctor if you have or have ever had a kidney, heart, or lung transplant; kidney disease; a joint or tendon disorder such as rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function); or if you participate in regular physical activity. Also tell your doctor if you have ever had any tendon problems during or after your treatment with norfloxacin or another quinolone or fluoroquinolone antibiotic. Tell your doctor and pharmacist if you are taking oral or injectable steroids such as dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), or prednisone (Sterapred). If you experience any of the following symptoms of tendinitis, stop taking norfloxacin, rest, and call your doctor immediately: pain, swelling, tenderness, stiffness, or difficulty in moving a muscle. If you experience any of the following symptoms of tendon rupture, stop taking norfloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or bear weight on an affected area.

Taking norfloxacin may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death. Tell your doctor if you have myasthenia gravis. Your doctor may tell you not to take norfloxacin. If you have myasthenia gravis and your doctor tells you that you should take norfloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment.

Talk to your doctor about the risks of taking norfloxacin.

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Simulation of hip fracture in sideways fall using a 3D finite element model of pelvis-femur-soft tissue complex with simplified representation of whole body. Together, these data indentify endostatin-XV as an angiogenesis inhibitor, which differs from endostatin-XVIII in several important functional details. Association between tumorigenic potential and the fate of cancer cells in a syngeneic melanoma model. Synthesis and photoinduced intramolecular flagyl medication effectiveness processes of fulleropyrrolidine-oligothienylenevinylene-ferrocene triads. We conclude that temporary clipping in aneurysm surgery is a relatively safe procedure which facilitates the aneurysm neck dissection and enables neck obliteration in difficult cases.

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The orientations of these strategies are threefold: 1) architectural-acoustic design, 2) equipment design and, most importantly, 3) staff education. Determination of alditols by capillary electrophoresis with indirect laser-induced fluorescence detection. The most abundant genetic changes include DNA losses of chromosome arms 3p, 5q, 10q, 13q, and 17p and DNA gains of 3q, 5p, 8q, and 17q. Furthermore, the long-term clinical benefits of LVH regression have yet to be documented. To evaluate three-dimensional (3D) facial morphology in patients surgically corrected for unilateral cleft lip and palate (UCLP) following pre-surgical nasoalveolar molding (NAM). Here, we show suppression of several PCDH15 nonsense mutations, both in vitro and ex vivo. For 14 out of 16 patients clinical outcome was favourable with no evidence to date of recurrence since surgery. Given decreasing restriction costs, introducing restraining measures to cope with public goods free-riding issues is the ultimate advantageous solution for all participants, rather than avoiding its creation.

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It is concluded that the pathogenesis of BHV-1 abortion involves infection of vascular endothelial cells in multiple tissues including placenta and brain. The patients also had precocious costal calcification, small iliac bones, short femoral necks, coxa vara, short halluces and fused vertebral bodies, none of which has been reported previously in this entity. In particular, an anomalous origin of the left coronary artery from the pulmonary artery is a fatal condition in neonate with myocardial failure. In conformity with previous results from our laboratories it was found that the maximal rate of change in relative R-R intervals and the corresponding transmural pressure were higher during exercise than at rest, indicating that exercise increased the carotid baroreflex sensitivity and shifted its optimal buffering range to higher arterial pressures. Nonsynaptic communication takes place in different immune organs, which are innervated by sympathetic nerve terminals. Xanthogranulomatous pyelonephritis with pyonephrosis in a 4-year-old child. Developing optimized pretreatment processes with reduced or modified lignin content to minimize non-productive enzyme binding or engineering pretreatment-specific, low-lignin binding cellulases will improve enzyme specific activity, facilitate enzyme recycling, and thereby permit production of cheaper biofuels. A hand-search of relevant engineering, medical/chiropractic, and computer Index Medicus sources in disciplines that cover the variety of symptoms was gathered. We have characterized cDNAs that encode the full-length hydra alpha1(IV) chain.

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If glioblastomas and other cerebral gliomas are removed completely, the patients can be cured of their tumors. Copper sensitizes the mitochondrial permeability transition to carboxytractyloside and oleate. An MRI of the brain showed acute infarcts in the right inferior cerebellum (posterior inferior cerebellar artery territory) and the right upper medial medulla (direct penetrating branches of vertebral artery). Pro-inflammatory cytokines such as acute sinusitis levaquin dose interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) play a key role in the pathogenesis of osteoarthritis (OA). Echocardiographic evaluation of the cardiovascular effects of medetomidine, acepromazine and their combination in healthy dogs.

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ER and PAX8 are useful markers in identifying the transition and origination of these tumors. Linear-g-hyperbranched and cyclodextrin-based amphiphilic block copolymer as a multifunctional nanocarrier. Cells that lack ddTpp1 exhibit strongly impaired development in the presence of the lysosome-perturbing drug chloroquine, and this phenotype can be suppressed through a secondary mutation in the gene that we name suppressor of tpp1(-) A (stpA), which encodes a protein with some similarity to mammalian oxysterol-binding proteins (OSBPs). Scientists mine web search data to identify epidemics and adverse events. The phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway plays a major role in the regulation of breast cancer growth and survival, but the clinical value of its components in human tumours is unclear. Topological aspects of interfaces are studied by comparing quantitatively the evolving three-color patterns in three different models, such uptodate levaquin dose as the three-state voter, Potts, and extended voter models. An evidence-based approach to the efficient use of computed tomography imaging in the neurosurgical patient. Multiple studies report significant interpersonal stress between family members of nursing home residents and facility staff members. Seven microsatellite markers in the vicinity of the CDKN2A gene were used to determine whether the mutation in these families is identical by descent, or represents a mutational hotspot in the CDKN2A gene.

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