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Metrozole (Metronidazole)

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Metrozole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Amebidal, Amrizole, Asuzol, Biozyl, Clont, Collazole, Colpofilin, Dazotron, Dequazol, Flagemed, Flazole, Giardyl, Ginkan, Gnostol, Gynomix, Mecozol, Metrocev, Metrodal, Metroderme, Metrol, Metrolag, Metrolyl, Metronidazol, Metronidazole, Metronidazolum, Metrosa, Metrozol, Negazole, Nidagel, Orogyl, Riazole, Rodogyl, Rozex, Rupezol, Stomorgyl, Taremis, Trichazole, Trichostatic, Trichozole, Tricofin, Tricozyl, Zidoval

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Also known as: Metronidazole


Metrozole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metrozole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Metrozole 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Metrozole and 250 on the other side; bottles of 50, 100, and 2,500. Metrozole 500-mg tablets are oblong, blue, film coated, with Metrozole debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


Single oral doses of Metrozole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Metrozole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Metrozole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Metrozole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


To reduce the development of drug-resistant bac- teria and maintain the effectiveness of Metrozole and other antibacterial drugs, Metrozole should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

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No quantitative systematic review or meta-analysis of population-based epidemiological studies has been conducted to assess the association between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of depression. Testing the Blastocystis isolates, different MLCs were obtained for all substances, whereas the Tetratrichomonas gallinarum isolates showed identical susceptibilities. The small size of this sample, and the heterogeneity of measures and scales used to capture conditions of poverty, make it difficult to assess the strength and consistency of associations between various poverty indicators and dengue outcomes. These findings may in part explain the large interpatient variation and the conflicting views regarding GC receptor content and prognosis in acute lymphoblastic leukemia. Sensitivity and prognostic value of early CT in occlusion of the middle cerebral artery trunk.

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It has recently been proposed that transcriptional targeting of therapeutic genes could be harnessed as a gene therapy strategy for the treatment of pituitary disease. Some aspects of the geographic comparative pathology of tegumentary leishmaniasis in the American tropics. Mandibular condyle dislocation into the middle cranial fossa is often misdiagnosed initially because of its low incidence and nonspecific symptoms. Potentiometric/turbidometric titration of antiperspirant actives. It is therefore tempting to speculate that the migration of neural precursor cells actually represents the normal counterpart of glioma cell migration. HIV-related diarrhea and cachexia are tremendously serious problems in developing countries where there is little access to antiretroviral medications.

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The utility of lymph node mapping to improve staging in colon cancer is under evaluation. A 55-year-old woman presented to our hospital with symptoms of chronic cholecystitis. Considerable evidence now points to an important role for the immune system in experimental models of atherosclerosis. This case report describes the ultrasonographic findings during an idiopathic spontaneous abortion in an owl monkey. Effect of dialysis dose and membrane flux in maintenance hemodialysis. In this study, instrumentation for measuring vapor sorption enthalpies and sorption uptakes simultaneously with an isothermal microcalorimeter is introduced. The frequency of IgE antibodies specific to inhalant and food allergens in adult asthmatic patients in Riyadh, Saudi Arabia. The most critical component of reproduction in beewolf females is flying with paralysed honeybees, which more than double their weight. Properties and applications of a new type of iodinated gradient medium. Introducing a school-to-work transition model for youth with disabilities in South Africa.

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Older age is an important factor in preparing travelers owing not only to physiologic changes and the increased probability of underlying medical conditions and prescription medications but also to immune status with regard to naturally acquired immunity versus immunization for vaccine-preventable diseases. Methods are described for rapid and economical production of large quantities of foot-and-mouth disease virus in stationary cultures of trypsin-dispersed bovine kidney cells in a simple medium. Bootstrap-based statistical thresholding for MEG source reconstruction images. Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients. A more complex model is proposed in which drugs and metabolites are incorporated into hair during formation of the hair shaft (via diffusion from blood to the actively growing follicle), after formation (via secretions of the apocrine and sebaceous glands), and after hair has emerged from the skin (from the external environment).

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One of these cannot be seen in coupled integrate-and-fire models and is peculiar to resonate-and-fire models. There may be a requirement for non-specialists to provide care with fewer resources than would be available in a specialist unit in the UK. This was a prospective randomized study of 20 myopic eyes (10 patients) who had LASIK using the Nidek NAVEX excimer laser system. Whereas TNF-alpha had little effect, IL-1 beta augmented IL-2 mRNA expression and IL-2 production by mitogen-stimulated cells. Combined with a multidisciplinary approach that includes nutritional rehabilitation and psychotherapy, adjunctive pharmacotherapy may be useful in addressing both eating disorder psychopathology and comorbid psychiatric disorders. Acute renal failure is a rare but serious complication of pregnancy. Far fewer injury surveillance systems exist within community sport than elite sport.

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Cortical distal nephron Cl(-) transport in volume homeostasis and blood pressure regulation. The mean pain period until the performance of the thermal ablation was 11.5 months (range 5-18 months). Therefore, oral health education and promotion is required to improve oral hygiene practices and health among young adults and the general population. To characterize the range of human epithelia that use MAL-mediated pathways of transport, we performed an immunohistochemical survey of normal tissues using a monoclonal antibody (MAb) specific for the MAL protein. Synthesis and characterization of nitrogen-rich macrocyclic ligands and an investigation of their coordination chemistry with lanthanum(III). The concentrations of sulfur-containing amino acids, taurine, cystathionine, methionine and cystine, as well as cystathionine beta-synthase and gamma-lyase activities in various tissues of Agkistrodon blomhoffi (mamushi) were measured. Moreover, patients whose blood pressure is controlled while using four or more antihypertensive medications are also considered controlled resistant hypertensive (CRH) subjects.

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The aim of this review is to provide the available evidence of the role of Smac/DIABLO in colon carcinogenesis. Ascaris lumbricoides and Taenia saginata eggs were found in the linen and strip fragment contents of the jar, dated of 2,715-2,656 years ago. The objective of this study was to investigate the role of the POU family transcription factor, Oct-4, in the early development of porcine embryos. coli and co-immune precipitation in yeast, that Dph1 and Dph2 interact and that they form a complex with Dph3. A total of 189 numerical printouts of the visual fields of 189 eyes of individuals either suspected of or verified as having glaucoma and displaying varying degrees of glaucomatous visual field damage were analyzed by one expert interpreter. The viral RNA-dependent RNA polymerase NS5 plays an important role in virus replication and represents an interesting target for the development of specific antiviral compounds. Nine compounds were isolated from the EtOAc extract in the rhizoma of Pleione bulbocodioides.

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Development of angiogenesis inhibitory combination therapies for treatment of renal cell carcinoma. In vitro establishment of human fibroblasts of lysosomal diseases, GM1-gangliosidosis and Sandhoff disease, by transformation with origin-minus SV40 DNA. The role of rpoS, hmp, and ssrAB in Salmonella enterica Gallinarum and evaluation of a triple-deletion mutant as a live vaccine candidate in Lohmann layer chickens. The aim of this study is to further examine this issue by analyzing a large sample of psychotic probands and their first-degree relatives. A modification of cryosurgery for the management of elevated bleb. Age group-specific and standardised overall and truncated (50-79 years old) rates were calculated by the direct method (European standard population).

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Negotiations about the Muslim cemetery in Switzerland: an example of religious recomposition in the context of immigration. Isoflurane attenuates LPS-induced acute lung injury by targeting miR-155-HIF1-alpha. One-hundred sixty-one women who were recent victims of sexual or nonsexual assault were assessed prospectively for 12 weeks. Six days after surgery, rats were trained to 5/10 criterion in one of the following conditions: within-modality direct, within-modality reversal, crossmodality direct, crossmodality reversal, or no training control. The influence of stocking density on body weight, egg weight, and feed intake of adult broiler breeder hens.

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The wire was advanced into the subintimal and failed to re-enter the true lumen. We also confirmed the results obtained by performing the corresponding immunofixation electrophoresis (IFE). One of these, the small GTPase RhoC, enhances metastasis when overexpressed, whereas a dominant-negative Rho inhibits metastasis. In this study we aimed to determine the prevalence of probable HIV dementia (PHD) in an HIV clinic population in Uganda and to delineate the factors associated with such impairment in these HIV positive individuals. Only this combination prevented subsequent tumour spread and resulted in a significantly improved survival, justifying the need for further exploration of the combination of ablative therapies and TLR9 agonists in liver cancer.

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We further propose a robust technique to minimize the effect of non-corresponding regions such as the resected tumor and possible hemorrhage in the post-resection image. A possible underlying common pathogenic process of these two side-effects of isotretinoin is discussed. Pivotal phase III trials have positioned angiogenesis inhibitors as first-line therapy for the management of most advanced or metastatic renal cell carcinomas (mRCC). Characterization of a novel monoclonal antibody against human perforin using transfected cell lines. A considerable amount of new amoxil 875 mg information on HIV immunology has been generated over the past several years using novel techniques designed to assess HIV-specific immune responses.

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canis antigens recognized early in the infection as the 19-, 37-, 75-, and 140-kDa proteins. No virus-like particles were seen associated with other cellular blood elements nor were they observed in blood samples obtained prior to virus inoculation. We report preclinical data and the results of a clinical Phase I study with the novel nonpeptide CRF(1) antagonist NBI-34041/SB723620. A series of traits related to hydraulics (vulnerability to cavitation and hydraulic conductivity in branches), growth performance and leaf mass per area were assessed in eight Pinus canariensis populations growing in two common gardens under contrasting environments. Obese women with PCOS showed decreased insulin sensitivity and hyperinsulinemia to an extent greater than can be explained by obesity alone. The can zithromax treat a kidney infection relative amounts (R values) of L(DEX) and L(MPC) associated with the heavy chains H(DEX), H(CHI) and H(ARS) in the assembled immunoglobulin molecules were found to be 1.02, 0.64 and 0.05, respectively, suggesting that the complementarity-determining regions and framework regions contribute equally to the V(L)-V(H) interaction. The highest performing map controlled over 13 out of 15 joints accurately.

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Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns. Dipsogenic potentiation by sodium chloride but not by sucrose or polyethylene glycol in tuberomammillary-mediated polydipsia. Receptor phosphorylation has been proposed as a possible regulator of the interaction between the receptor and its intracellular and extracellular ligands. Comparison of fasting and 2 hours postprandial blood glucose in the control of patients with type 2 diabetes. estimation of RNA or proteins immunoprecipitated from transformed cells often provide partial or ambiguous definition of autoantibody specificity. But many chemicals control could increase resistance in target species, toxicity and environmental hazards. This suggests that the EnvZ HAMP domain by itself is unable to form a stable structure and that this structural fragility may be important for its role in signal transduction.

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Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial: methodology. This measure controlled for variations in DNA extraction and PCR efficiency among the samples to be compared. Nanosystems of polymeric nature in particular have been investigated over the last years and their interactions with mucosal fluids and tissues, as well as genital tract biodistribution upon vaginal administration, are now better understood. A retrospective levaquin classification of drug review was made of medical records of all patients admitted to King Fahad National Guard Hospital with brucellosis during the period from 1984 to 1995. We examined whether differences were present in pretreatment and during-treatment overall income, as well as specific income sources.

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The pulmonary Kulchitsky cell (neuroendocrine) cancers: from carcinoid to small cell carcinomas. Problems of diagnostic procedures in cases of POVT and the role of ureaplasma and mycoplasma in infectious obstetric complications are discussed. The authors evaluated the roles of TGFalpha in chronic viral hepatitis ( flagyl tablet 500 mg CVH) and hepatocellular carcinoma (HCC). Approching to pH 1.0, the bands B-DNA and C-DNA almost disappeared, the new bands at 891, 1265 and 1418 cm(-1) appeared at the same time and the intensity of 891 and 1265 cm(-1) increased, but the intensity of 1418 cm(-1) became weaker. Thin-layer chromatographic detection of cocaethylene in human urine. donovani infection of BMMs was found to induce gene expression for granulocyte-macrophage CSF, TNF-alpha, TGF-beta, and IL-6, but not M-CSF or IL-1 beta. Plasma brain natriuretic peptide (BNP) level increases in proportion to the degree of right ventricular dysfunction in pulmonary hypertension. Endostatin and doxorubicin synergized to down-regulate VEGF expression. In addition, the effects of select FC and patient characteristics on each of the CRA subscales were evaluated.

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The main hypothalamic neuronal circuit in the regulation of energy metabolism is the melanocortin system. This article focuses on the state of animal model development for 3 agents for which models are largely immature: Francisella tularensis, Burkholderia mallei, and Burkholderia pseudomallei. Comparison of defocusing and fractional Fourier transform in spectroholographic storage. The time domain method combines the use of second- and third-order correlations to reveal information on the stationarity of periodic spindle rhythms to detect transitions between multiple activities. The lowest frequency collective modes predicted by ANM show that the 50S subunit and 30S subunit are strongly anti-correlated in the motion of the 70S assembly. We found that a highly attenuated bacterium Listeria monocytogenes (Listeria(at))-infected what kind of antibiotic is cleocin MDSC and altered the immune-suppressing function of MDSC. The present study sought to develop and operationalize the construct of moral concern or worry in a psychiatric outpatient sample and to investigate relationships between moral worry and age, gender, religiosity, and the tendency to worry in general.

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