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Metrocreme (Metronidazole)

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Metrocreme is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Anaeromet, Anamet, Anerozol, Arilin, Avidal, Buccoval, Dumozol, Elyzol, Flagicure, Ginerella, Imizine, Klion, Metren, Metrocreme, Metronex, Metropast, Metryl, Molazol, Nidazea, Protogyl, Rosaced, Rosiced, Rozacrme, Tricofin, Trogyl, Vagizol

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Vantin, Myambutol, Noroxin, Sumycin, Rulide, Floxin, Chloromycetin

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Also known as: Metronidazole


Metrocreme (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metrocreme is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to con- tinue the seven-day regimen. A seven-day course of treatment may minimize reinfection by pro- tecting the patient long enough for the sexual con- tacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regi- men better than the other.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Metrocreme overdose, Metrocreme infusion should be discontinued. Patients should be treated symptomatically.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metrocreme are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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all cases of ARF complicating repair of ruptured AAAs treated at Leicester General Hospital between 1984 and 1996 were identified in a retrospective study based on review of clinical records. This revised technical report draws on previously published policy statements and reports, reviews the current literature, and describes the present state of practice and research regarding patient- and family-centered care for children in the emergency department setting as well as some of the complexities of providing such care. We tested the hypothesis that nitric oxide can inhibit cytoskeletal breakdown in skeletal muscle cells by inhibiting calpain cleavage of talin. This review discusses the efficacy of current pre-erythrocytic-stage, asexual blood-stage, and transmission-blocking vaccine candidates, as well as future prospects for malaria vaccine development. The primary reasons for this study are the growing scarcity of freshwater in the world, recurrent problems in managing this resource and a desire to contribute to the improvement of the current situation.

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Study on the association of single nucleotide polymorphisms and haplotypes of GPR154 gene with allergic asthma in Han nationality in Hubei Chinese population. We know now that clinical evolution will depend of host factors as well as of viral characteristics. An ensemble learning approach that combines different encodings using a meta-learner was developed which was catalyzed by four protein kinase families and three residues. The anti-tumor activity of IL-12: mechanisms of innate immunity that are model and dose dependent. We then studied the effects of USP22 silencing by shRNA on NSCLC cell growth in vitro and tumorigenesis in vivo, along with the effect on the p53 pathway. Two hundred and ninety-two Caucasian children presenting with isolated hypospadias without micropenis or cryptorchidism and 345 controls were included prospectively.

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A total of 47 testicular biopsies from patients with varicocele, obstructive azoospermia and idiopathic infertility were included. This renders their health needs invisible and reaffirms them as capable caregivers. Thioredoxin, a 12-kDa protein with a catalytically active disulfide group, has recently been found to reduce intramolecular disulfide bonds in a variety of proteins. The purpose of the study was twofold: (1) to evaluate the reliability of distance measures computed from a principal component analysis (PCA) of electromyographic (EMG) waveforms of trunk muscles recorded during standardized trunk movements and (2) to evaluate their sensitivity to the load lifted, the trunk range of motion (ROM) and to low back status. The purpose of this study was to elucidate the pharmacokinetics of each enantiomer of lansoprazole and 5-hydroxylansoprazole in three different CYP2C19 genotype groups of Japanese subjects. We have developed novel metrics, called semantic similarity and semantic interactivity, which use Gene Ontology (GO) annotations to measure the reliability of protein noroxin brand name -protein interactions. Seven of 12 SLE, 6 of 8 PSS, 3 of 6 PM/DM and all 3 AGA patients showed an abnormal tracer uptake. By immunofluorescence all four islet cell types were found in the tumors, though with different frequency. Classification of mental disorders has been greatly influenced by a medical model postulating biological abnormalities that underlie its divisions. Effect of host behaviour on host preference in Stomoxys calcitrans.

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Two inflammatory markers, leucocyte count and neutrophil ratio, were evaluated for diagnosing acute appendicitis. Colocalization of Y2 receptors and GHRH in the arcuate nucleus (Arc) suggests that GHRH mRNA expression in this region might be directly regulated by Y2 receptors. Expression of the cytochrome P-450(11)beta gene is tissue specific in that these transcripts were not detected in liver, heart, kidney, or corpus luteum. The physicochemical and microbial characteristics of some medium-temperature hydrotherms of Kamchatka Peninsula (Uzon caldera), habitats of the hoverfly Eristalinus sepulchralis larvae, were studied. Preparing students for the emotional challenges of nursing: an integrative review.

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A large administrative database was used to study outcomes, complications, and trends in utilization of surgical and endovascular treatments for epistaxis. Effects of phenytoin and flunarizine on the rise in extracellular potassium induced by repetitive stimulation of rat cerebral cortex. We determined that non-flowing, unclotted blood has intermediate T1 characteristics and long T2 characteristics. Glycomacropeptide (GMP) is a whey protein that contains no aromatic amino acids including phenylalanine (phe). The research explosion that followed the discovery of TLRs more than a decade ago has boosted fundamental knowledge on the function of the immune system and the resistance against disease, providing a rational for clinical modulation of the immune response. 8 patients with an advanced non-resectable tumor, or who were unfit for surgery, were thus treated. Important factors identified by univariate analysis were selected as covariates to construct a multivariate proportional hazards model for survival. However its efficacy against Enterococcus faecalis biofilm, which is associated with persistent root canal infection is unknown. In family A, the knee joint was commonly affected, followed by the ankle joint.

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