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Metazol (Metronidazole)
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Metazol

Metazol eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Aldezol, Aldezole, Amobin, Asuzol, Birodogyl, Colpofilin, Corsagyl, Deflamon, Fladex, Flagystatin, Giardyl, Ginerella, Kilpro, Klont, Lindoplus, Metronidazole, Metronour, Metroson, Metrozine, Metrozole, Minegyl, Nalox, Orvagil, Padet, Polibiotic, Rodogyl, Rozex, Supplin, Trichodazol, Tricodazol, Tricozyl, Trogyl, Vandazole, Zyomet

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Terramycin, Vantin, Keflex, Chloromycetin, Cefixime, Zithromax, Rulide, Duricef, Avelox

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Also known as: Metronidazole

Description

Metazol (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metazol is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

The usual adult oral dosage is 7.5 mg/kg every six hours (approx. 500 mg for a 70-kg adult). A maximum of 4 g should not be exceeded during a 24-hour period.

The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment.

Patients with severe hepatic disease metabolize metronidazole slowly, with resultant accumulation.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Metazol overdose, Metazol infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Metazol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Generic Metazol if you are allergic to Generic Metazol components. Be very careful if you're pregnant or you plan to have a baby, or you are a nursing mother. Try to be careful with Generic Metazol usage in case of having kidney or liver disease, nerve disorders, epilepsy, leukopenia, anemia, seizure disorder, stomach or intestinal disease, blood cell disorder. Try to be careful with Generic Metazol usage in case of taking blood thinner such as lithium (Lithobid, Eskalith), cimetidine (Tagamet), warfarin (Coumadin), disulfiram (Antabuse); seizure medication such as phenobarbital (Luminal, Solfoton), phenytoin (Dilantin). Try to be careful with sunbeams. Generic Metazol makes skin sensitive to sunlight. Protect skin from the sun. Try to avoid machine driving. Generic Metazol can be dangerous for children. Avoid alcohol. It can be dangerous to stop Generic Metazol taking suddenly.

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PCB impairs smoltification and seawater performance in anadromous Arctic charr (Salvelinus alpinus). Although clinical guidelines generally portray chronic low back pain as a condition with a poor prognosis this portrayal is based on studies of potentially unrepresentative survival cohorts. Blood pressure, ECG and MSNA waves were changed to equidistant time series data of each second by cubic spline interpolation. This case demonstrates how a benign FDG-avid foreign body reaction, induced by an intact breast prosthesis, could easily be mistaken for malignancy. Furthermore, high positive mood (marginally) instigated high risk-taking, and in turn engaging in risk-taking resulted in increased positive mood. We conclude that aberrant expression of NCAM on tumor cells of different histogenetic origin can lead to inhibition of target cell recognition and lysis by NK cells. We have retrospectively reviewed 112 cases of in situ carcinoma of the breast treated between 1960 to 1972, with a minimum 10 year follow-up to correlate treatment with outcome. There is lack or poor evidence on the need for specific drugs to reduce triglycerides, to increase HDL-cholesterol, to improve insulin sensitivity or to decrease abdominal obesity.

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An imbalance between pro-oxidants and antioxidant systems has been suggested to be implicated in the physiopathology of acute myocardial infarction (AMI). A cost-effectiveness study of 4 strategies using a theoretical model showed that the risk strategy (antibiotics for women at risk) and combination strategy (antibiotics for GBS-positive women at risk) seemed more cost-effective than the current Dutch strategy (antibiotics for women at risk ifGBS positive) and the screening strategy (antibiotics for GBS-positive women). The questionnaire also attempted to evaluate the effects on the self-esteem of the women, as well as the impact of religious dogma and the related beliefs. HIV-1 infection as a risk factor for the development of tuberculosis: a case-control study in Tanzania. Formal evidence of monoclonality was obtained in one case which was of human IgG1 isotype and was secreted at the level of 15-20 micrograms/ml. Isodicentric X chromosome and mosaicism: report on two cases of 45,X/46,X,idic(Xq)/47,X,idic(Xq),idic(Xq) and review of the literature. Rather remarkably, LI appears to be resistant to the effects of numerous lesions, including the prefrontal cortex (PFC) and the basolateral amygdala (BLA). Citrate and P-enolpyruvate inhibited the enzyme non-competitively with fructose 6-phosphate and independently of the concentration of inorganic phosphate. The possible involvement of delta receptors in morphine-induced dependence was studied by monitoring the abstinence behaviour precipitated in rats given pellets of morphine by either ICI 154129 or naloxone. Shorter remission period in young versus older children with diabetes mellitus type 1.

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This study investigates the long-term effects of childhood sexual abuse (CSA). The heart rate variability (HRV) is an extended tool to analyze the mechanisms controlling the cardiovascular system. The activity of the predominant bacteria was monitored by direct ribosome isolation from soil and temperature gradient gel electrophoresis of reverse transcription (RT)-PCR products generated from bacterial 16S rRNA. Several experiments suggest that negative regulation of gene expression by the glucocorticoid receptor accounts for its anti-inflammatory action. Projections are based on synthesis of multiple scholarly, professional, and governmental sources of information. The current taxonomic status of the Culicoides vectors of bluetongue viruses.

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ECP treatment is FDA approved for the treatment of cutaneous T-cell lymphoma (CTCL) with particularly promising results seen in graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HCT). The high sensitivity of the luminol chemiluminescent assay was achieved with Mo-ethylenediaminetetraacetate complex and menadione or coenzyme Q1. Effect of pharmacologic agents on the function of the hypothermically preserved dog kidney during normothermic reperfusion. Pathologic alterations have been found in myocardium, lungs, liver, pancreas, thymus, brain and spinal cord, adipose tissue, and skeletal muscles. We retrospectively analyzed all noroxin generic allograft renal transplants performed at our centre from 1996 to 2005. Furthermore, preliminary biodistribution study indicated that SPIO-exendin4 had a tendency to accumulate in pancreas. This article reviews advances in geriatric nursing theory, practice, and research based on the Progressively Lowered Stress Threshold (PLST) model that are designed to promote more adaptive and functional behavior in older adults with advancing dementia.

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