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Makrodex (Roxithromycin)
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Makrodex

Makrodex is a semi-synthetic macrolide antibiotic. It is a white crystalline powder. Makrodex is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Assoral, Azuril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Delos, Dorolid, Floxid, Infectoroxit, Klomicina, Ladlid, Macrolid, Macrosil, Makrodex, Monobac, Odonticina, Overal, Pedilid, Ramivan, Renicin, Rokilide, Rokithrid, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Romac, Romyk, Rossitrol, Rotramin, Roxithromycin, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

Similar Products:
Cefixime, Amoxil, Chloromycetin, Keflex, Flagyl, Biaxin, Rulide

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Also known as: Roxithromycin

Description

Makrodex is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Makrodex is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Makrodex is available under several brandnames. Makrodex is not available in the United States. Makrodex is available in Australia, Israel and New Zealand. Makrodex has also been tested to possess antimalarial activity.

Makrodex prevents bacteria from growing, by interfering with their protein synthesis. Makrodex binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Makrodex has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

Dosage

Makrodex is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.

Overdose

If you overdose Generic Makrodex and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Makrodex or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Makrodex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Makrodex if you are allergic to Generic Makrodex components. Try to be careful with Generic Makrodex if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Makrodex taking suddenly.

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