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Macrosil (Roxithromycin)

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Macrosil is a semi-synthetic macrolide antibiotic. It is a white crystalline powder. Macrosil is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid.

Other names for this medication:
Acevor, Asmetic, Assoral, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Dorolid, Elrox, Erybros, Floxid, Infectoroxit, Macrolid, Makrodex, Nirox, Odonticina, Overal, Pedilid, Pedrox, Ramivan, Redotrin, Remora, Ritosin, Rokithrid, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Rossitrol, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Omnicef, Cleocin, Avelox, Chloromycetin, Zithromax, Terramycin, Cipro, Amoxil, Biaxin

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Also known as: Roxithromycin


Generic Macrosil belongs to macrolides group of antibiotics which are prescribed for treating serious bacterial infections such as acute pharyngitis (sore throat and discomfort when swallowing), tonsillitis, sinusitis, acute bronchitis (infection of the bronchi causing coughing), pneumonia (lung infection characterised by fever, malaise, headache), skin and soft tissue infections, non gonoccocal urethritis, impetigo (bacterial infection causing sores on the skin). It acts on the bacteria which causes the above mention bacterial infections caused by the bacteria. It kills completely or slows the growth of these sensitive bacteria in our body. Generic name of Generic Macrosil is Roxithromycin. Macrosil is also known as Roxithromycin, Roximycin, Biaxsig, Roxar, Surlid. Brand name of Generic Macrosil is Macrosil.


Macrosil is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Macrosil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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A monoclonal antibody D51 recognizes the transferrin-receptor structure. Microfluidic devices, which constrain fluids to a small (typically submillimeter) scale, facilitate analysis of platelet function, coagulation biology, cellular biorheology, adhesion dynamics, and pharmacology and, as a result, can be an invaluable tool for clinical diagnostics. Nurse intervention appears to help those with the least knowledge of epilepsy improve their knowledge scores. In EC, G(alphai) directly interacts with SRC and this interaction leads to SRC activation and phosphorylation in a manner that is regulated by beta(2)AR stimulation. Hyper-IgD syndrome and familial Hibernian fever are true periodic fever syndromes. Hemodynamic parameters in patients with acute cervical cord trauma: description, intervention, and prediction of outcome. Action of cortisone on the levels of hepatic iron in the rabbit of both sexes.

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Among the mechanisms suggested for the prothrombotic activity of lupus anticoagulant and antiphospholipid antibodies is the direct inhibition of the anticoagulant activated protein C (APC) pathway. Large scale subfractionation of THP-1 cells determined that while cytoplasmic lipid droplets constituted much of the total NMR-visible lipid, the contribution of DRMs was significant. Refuelling by migratory birds before take-off on long flights is generally considered a two-phase process, with protein accumulation preceding rapid fat deposition. Analycys: a database for conservation and conformation of disulphide bonds in homologous protein domains. TAS in all samples was determined by spectrophotometric and enzyme-linked immunosorbent assay methods.We studied the possible association of the TAS level with various clinical indices relevant to POAG. The primary objective of this paper was to determine the extent and nature of interspecies differences in axon calibre and myelin sheath thickness and in the various relationships between these. Home range size in mammals is a key ecological trait and an important parameter in conservation planning, and has been shown to be influenced by ecological, demographic and social factors in animal populations. The method also detects the presence of the CYP21A1P/CYP21A2 chimeric gene.

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Individuals carrying high-risk alleles of both rs6502867 and rs2670660 had an odds ratio of 4.20 compared with individuals carrying a high-risk allele from only one signal. Neurodevelopmental outcome of infantile spasms: A systematic review and meta-analysis. From an Utstein database, we assessed survival to admission and comorbidity with the Charlson comorbidity index from the National Patient Registry and employment status from the Danish Rational Economic Agents Model database. Health status assessment tool for the family member caregiver of patients with bipolar disorder: development and psychometric testing. The Experimental Inoculation of Foxes with Formalized Tissue of Infected and of Healthy Ferrets During an Epizootic. The appendix and cecum were mobilized, and the tip of the appendix was anastomosed directly to the skin of the right lower quadrant through 1 of the 5 mm. We validate the predicted target regions of Grainyhead by ChIP-seq and identify this factor as a general cofactor in the eye network, being bound to thousands of nucleosome-free regions. Reactive Intermediates on Metal Surfaces: A Ketene Monolayer on Single Crystal Platinum Generated by Photolysis of Pyridyl alpha-Diazoketones This research was supported financially by the Natural Science and Engineering Research Council of Canada (NSERC), The University of Western Ontario ADF, and the Canadian Foundation for Innovation. Intravenous magnesium in the treatment of hydrofluoric acid burns in rats.

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Compared to the original ethambutol name brand annotation, we increased the number of proteins with predicted functional features from 349 to 458. Rapid detection of sex chromosomal aneuploidies by QF-PCR: application in 200 men with severe oligozoospermia or azoospermia. These mutations are not important risk factors for thromboembolic stroke associated with atrial fibrillation. Clams (Dosinia exoleta, Ruditapes philippinarum, Venerupis pullastra, Venerupis rhomboideus, Venus verrucosa), mussels (Mytilus galloprovincialis), and oysters (Ostrea edulis) were tested for the presence of Cryptosporidium sp. Consumption of these interferences prior to light emission results in a lag time and a less favourable HRP detection limit. Despite the decreased chest expansion and the significantly reduced lung volume in adults with cerebral palsy, sufficient oxygen supply was registered.

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Review of the orthopedic omnicef drug interactions oncology and pathology databases yielded 51 cases of histologically proven nodular fasciitis. After extracting the process water with butyl acetate, the debromination reaction of the remaining organic bromine is considerably smaller. Fungal and bacterial cultures were negative in both eyes of both patients. We suggest that good initialization of EM is critical and can be achieved via spectral clustering. This study sought to extend the literature by examining the association between peer victimization, child depressive symptoms, parent distress, and health-related QOL in overweight youth. We reviewed five patients with the injury, presenting over a two-year period. An analysis of the viral amino acid sequence of the M2 protein of the recent strain revealed a V27A mutation, which is associated with amantadine resistance in avian influenza virus. Effects of the environmental factors on the casein micelle structure studied by cryo transmission electron microscopy and small-angle x-ray scattering/ultrasmall-angle x-ray scattering. The EUS-BD technique is currently limited by a lack of dedicated devices and large data reporting outcomes and complications.

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Multiplex analyses allowed a distinct HPL growth factor profile to be delineated. The aim of this study was to determine how the treatment needs and outcomes of polysubstance-using patients entering opioid-substitution treatment (OST) may be affected if the patient had a parent with substance-use problems. New models of clinical education are required, to take account of changes in the patient population, disease profile and management strategies. Research into phagosome biogenesis has flourished in recent years - the purpose of this review is to give a glimpse of where this research stands, with emphasis on the cell biology of macrophage phagosomes, on new model organisms for the study of phagosome biogenesis and on intracellular pathogens and their interference with normal phagosome function. Neurotransmitters are released from nerve terminals and neuroendocrine cells by calcium-dependent exocytosis of vesicles. Cross-linking of BCR rapidly induces protection of B cells from Fas-mediated apoptosis, which has been assumed one of the important survival mechanisms of B cells during antigen stimulation.

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In plants, microRNAs (miRNAs) comprise one of two classes of small RNAs that function primarily as negative regulators at the posttranscriptional level. A correlational test of the relationship between posttraumatic growth, religion, and cognitive processing. This study shows a further characterization of vasopressin-containing cells of the rat hypothalamus. This paper presents an application of multiagent system to the analysis of gene expression data. Physical geography and particularly natural geomorphologic processes like erosion, mass movement, physical weathering, and chemical weathering features etc. A significant number of deaths in people with epilepsy may be potentially preventable through better seizure control, regular monitoring and raising awareness among patients and carers. Engineering and characterization of a single-chain antibody fragment (scFV1924) against the human sarcoma-associated antigen p102. Weekday distribution of alcohol consumption in Norway: influence on the occurrence of epileptic seizures and stroke?. Patients with a high plasma level of factor VIII have an increased risk of recurrent venous thromboembolism. Although these approaches have yielded valuable data, the results highlight the fact that only the limited numbers of proteins are characterized at the protein level in these cells, thus necessitating expandable MSC proteome dataset.

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