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Macrobid (Clarithromycin)
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Macrobid

Macrobid is also effective against some infections (e.g., MAC or Mycobacterium avium complex) seen in people with reduced immunity. It stops the bacteria from growing, which helps to resolve your symptoms and cure your infection. This medicine is taken orally, preferably either one hour before or 2 hours after a meal.

Other names for this medication:
Aeroxina, Bacterfin, Binoclar, Clamycin, Claripen, Clariston, Clarithromycin, Claritrox, Clariva, Clarix, Claromac, Claron, Claryl, Clasine, Cleron, Clormicin, Derizic, Egelif, Eracid, Euromicina, Ezumycin, Fromilid, Geromycin, Helimox, Kalixocin, Karid, Karin, Klarimac, Klarimax, Klarithrin, Laricid, Larithro, Larizin, Macladin, Maclar, Odycin, Preclar, Veclam, Vikrol, Xylar, Zeclar, Zeclaren

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Also known as: Clarithromycin

Description

Macrobid (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Macrobid works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

Macrobid Filmtab and Macrobid Granules may be given with or without food.

Macrobid XL Filmtab should be taken with food. Swallow Macrobid XL Filmtab whole; do not chew, break or crush Macrobid XL Filmtab.

Triple therapy: Macrobid Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Macrobid Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Macrobid Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Macrobid Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Macrobid Filmtab/omeprazole. The recommended adult dosage is 500 mg Macrobid Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Overdose

If you overdose Macrobid and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Macrobid overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Macrobid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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