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Levaquin

Levaquin is used to treat bacterial infections in many different parts of the body. It is also used to prevent an anthrax infection after a person has been exposed to anthrax. This medicine is also used to treat and prevent plague (including pneumonic and septicemic plague).

Other names for this medication:
Acquire, Alevokem, Anlev, Armolev, Cinacol, Corbic, Elequine, Glevo, Laiwoxing, Leflumax, Lefos, Lekuicin, Letab, Levobact, Levocine, Levoday, Levof, Levofloxacin, Levofloxacina, Levofloxacinum, Levogen, Levolacin, Levonix, Levotac, Levovid, Levoxal, Levunid, Loxof, Medibiox, Oftaquix, Orlev, Priflox, Prixar, Quantrum, Quixin, Resquin, Rinvox, Rodixina, Tivanik, Truxa, Ultraquin, Uniflox, Voflaxin, Zidalev

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Also known as: Levofloxacin

Description

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Levaquin and other antibacterial drugs, Levaquin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Levaquin Tablets/Injection and Oral Solution are indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed in this section. Levaquin Injection is indicated when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).

Dosage

Administer Levaquin with caution in the presence of renal insufficiency. Careful clinical observation and appropriate laboratory studies should be performed prior to and during therapy since elimination of Levaquin may be reduced.

No adjustment is necessary for patients with a creatinine clearance ≥ 50 mL/min.

Overdose

Overdose of the drug should be strictly avoided and if anyone has accidentally taken the overdose of the drug, then the victim should be provided with emergency medical help. Overdose victim can also consult to their local poison helpline. Some of the overdose symptoms include loss of coordination, drooping eyelids, weakness, decreased activity, trouble breathing, sweating, tremors, or seizure.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Levaquin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Generic Levaquin if you are allergic to Generic Levaquin components. Be very careful if you're pregnant or you plan to have a baby, or you are a nursing mother. Try to be careful with Generic Levaquin usage in case of having history of convulsions, colitis, stomach problems, vision problems, heart disease, history of stroke, kidney or liver disease. Try to be careful with Generic Levaquin usage in case of taking anticoagulants ('blood thinners') such as warfarin (Coumadin); cimetidine (Tagamet); cisapride (Propulsid); cyclosporine (Neoral, Sandimmune); medications for irregular heartbeats such as amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), quinidine (Quinidex), and sotalol (Betapace, Betapace AF); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); phenytoin (Dilantin); pimozide (Orap); probenecid (Benemid); sucralfate (Carafate); theophylline (Theo-Dur); thioridazine (Mellaril); antibiotics; cancer chemotherapy agents. Avoid alcohol. Try to avoid machine driving. It can be dangerous to stop Generic Levaquin taking suddenly.

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The changes of masseter fibres show reconstruction of masseter muscle after mandibular angle ostectomy. Progress in the development of animal models of acute kidney injury and its impact on drug discovery. A total of 592 computed tomography examinations of the brain in children were studied from the aspect of age and development. Therefore, early and accurate diagnosis of cutaneous mastocytosis in children is essential for appropriate care. Interestingly, EGFR with exon 19-deletion/T790M double mutations, which was resistant to gefitinib, remained sensitive to PP2. The optimal treatment of HZ requires early antiviral therapy and pain management. Apoptosis were detected through acridine orange (AO) and ethylene dibromide (EB) staining and DNA fragmentation assay. By subdividing a lens design into simpler units it is possible to evaluate its mass and locate its centre of mass (the centroid). No Increased Risk of Second Cancer After Radiotherapy in Patients Treated for Rectal or Endometrial Cancer in the Randomized TME, PORTEC-1, and PORTEC-2 Trials.

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Furthermore, we found an end point of this transition line beyond which the two glasses become identical in their local structure and their long-time dynamics. In a model of cerebral ischemia and reperfusion, diabody administration (0.8 mg/kg, 1 hour postocclusion) led to a mitigated cerebral injury with a 2.3-fold reduced lesion and improved functional outcomes. In cross-cultural child development research there is often a need to translate instruments and instructions to languages other than English. Fourteen children with amblyopia and 14 normally sighted children underwent DTI scanning. Thus the enzymes were characterized with respect to substrate specificity and kinetics, inhibition kinetics and various other physico-chemical properties. Iodine in spot urine, serum total thyroxine (T4), serum free thyroxine (FT4), thyroid stimulating hormone (TSH), and thyroglobulin (Tg) were measured. At least three distinct processes can be differentiated: a memory of drug effects (reflected by a sensitization to drug effects etc.), a memory of drug use (reflected by controlled drug consumption), and a memory of addiction (reflected by a persisting loss of control over drug intake and correlating changes in striatal dopaminergic neurotransmission). Movement disorders caused by antidepressants, lithium, antiemetics, antiparkinsonian agents, anticonvulsants, calcium channel blockers, sympathomimetics and others are only briefly covered in table form. This study used biochemical and functional assays to evaluate whether ponatinib was different from the other BCR-ABL inhibitors with respect to platelet activation, spreading, and aggregation. On-line combination of high performance liquid chromatography with comprehensive two-dimensional gas chromatography-triple quadrupole mass spectrometry: a proof of principle study.

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Laparoendoscopic single-site nephrectomy and heminephroureterectomy in children using standard laparoscopic setup versus conventional laparoscopy. To study the influence of epidermal growth factor (EGF), neurotensin (NT) on cytosolic calcium and membrane fluidity in carbon tetrachloride-injured primary cultured hepatocytes. He was treated successfully by open reduction and miniplate fixation. gondii strains, respectively, were resolved by sodium- dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) then probed by immunoblot (IB) (Western blot) with mice antisera elicited by different states of toxoplasmosis to allow parallel analysis of antigen recognition by immunoglobulin G, M, and A antibodies. Our results show that SCI caused a loss of sensory input as well as structural remodeling such that the balance of nociceptive inputs and descending modulation was permanently altered. This involves, however, solving a challenging nonlinear and ill-posed electromagnetic inverse scattering problem. To define the transmembrane topology of the inositol 1,4,5-trisphosphate receptor (InsP3R), we determined the subcellular location of the hydrophilic segment (residues 2463-2529 of mouse type 1 InsP3R) believed to be located at the luminal side of the endoplasmic reticulum (ER) in the six-transmembrane model but at the cytoplasmic side in the eight-transmembrane model. Reversible left ventricular dyssynchrony and dysfunction resulting from right ventricular pre-excitation.

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The higher the perceived stress related to physical symptoms, dependency on medical staff, and blood vessel problems, the more the patients used emotion-oriented, support seeking, avoidance, and isolated thoughts to cope. The monolithic fetal pacemaker: prototype lead design for closed thorax deployment. Natural products have been an important source of lead compounds for drug discovery. Most designs that allow for an interim look are not appropriate for monitoring survival probabilities since many patients will not have enough follow-up by the time of the interim analysis, thus necessitating an inconvenient suspension of accrual while patients are being followed. The aim of this study was the preparation of reliable procedure of the determination of nicotine and cotinine both in classic (serum, urine) and alternative biological materials (hair, saliva) and evaluation of their significance for clinical and forensic toxicology. If the cost of immunosuppressive therapy is prohibitive because of rifampicin, rifampicin-sparing antituberculosis therapy can be successfully employed in RT patients. SPECT images were processed into four types: original SPECT images, three-dimensional stereotactic surface projection (3DSSP) images derived from them, Z-scores of SPECT images, and Z-scores of 3DSSP images. According to it, the spectrum of the in-phase/quadrature/envelope components are power-law functions. Immunoreactivity for the alpha 1, beta 2/3, and gamma 2 subunits is greatest in layers (II-III, IVA and IVC) of monkey area 17 that contain the highest density of GABA neurons and terminals. Furthermore, CT 3-dimensional reconstruction showed brain edema, fracture of the left posterior horn of the hyoid bone, and a grade 1 retrolisthesis of C5 on C6.

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Sample size tables for receiver operating characteristic studies. The paper presents echocardiographic findings of 91 patients with implantable pacemaker. Autogenous tooth transplantation is indicated in young people treated by orthodontology, especially when they present with damaged first molars requiring extraction. The rationale and study design of an active randomized, double-blinded, placebo-controlled trial of coumarin for RCC are discussed. Process of care failures in invasive cervical cancer: systematic review and meta-analysis. Studies on experimental animals (rats) have shown significant depression of circulating levels of T4 and moderate reductions in levels of T3 after exposure to PCBs. However, their relative abundance was different among cells of the same organism (leucocytes/sperm cells), and this trend was not maintained when the different species were compared.

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We have therefore evaluated lymphocytic infiltration in the slices of surgically removed thyroids in patients affected by thyroid carcinomas, to further clarify the anatomic and clinical characteristics of this pathology and the possible prognostic correlations. Venous malformations of the small intestine are rare in children, and the preoperative diagnosis of a venous malformation in the small bowel can be very difficult. Electronic patient record systems proved to be excellent information feeders to handover tools, but their role in collaborative grounding is unclear. The trypsin-like protein(s) are also involved in the induction of acrosome reaction. Most injections were performed to treat exudative age-related macular degeneration. In this article, we discuss the role of electron microscopy in diagnosis of spindle cell tumors and focus upon some more recently described entities.

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Weight loss in AD patients should not be attributed to long-term treatment with galantamine. The lowest-energy conformations of four carbocyclic lexitropsins, potential carriers of alkylating elements, were obtained using the HyperChem 4.0 program, and compared with the DNA-lexitropsin crystal structures from the Brookhaven National Laboratory Protein Data Bank. The proposed algorithm is applied to a number of images with skin lesions with known histo-pathology. But far from depersonalizing the consultation, the formalism of the diagnostic procedure is considered by some professionals as a political lever to empower women from poor neighbourhoods as they acquire knowledge and comprehension of the situation despite their lack of decisional autonomy. Circadian rhythms in the CNS and peripheral clock disorders: human sleep disorders and clock genes. Reduced blood flow, or reduced oxygenation, is critically important in an organ system with high energy needs like the cochlea. For several different reasons, it is beneficial to convert free-text guidelines gradually, through several intermediate representations, to a machine-interpretable format.

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Part 6: advanced cardiovascular life support: section 7: algorithm approach to ACLS emergencies: section 7A: principles and practice of ACLS. We report on a 78-year-old woman with a 47-year-history of lichen sclerosus et atrophicus of the vulva on which squamous cell carcinoma developed. In image-guided surgery and image-directed therapy a plan based on pre-procedure imaging is registered to the patient in the operating or treatment room using a 3D spatial localizer. As a result, we have a much-improved understanding of the variety of important pathways that function during chloroplast biogenesis. The regulation of miRNA expression could be a novel strategy in the chemoprevention of human gastric malignancy. The principle of modularity, yet largely unproven for biological systems, suggests that modules will function appropriately based on their design characteristics when combined into larger synthetic genetic devices. BCoS was designed for stroke-specific problems across 5 cognitive domains: (a) controlled and spatial attention, (b) language, (c) memory, (d) number processing, and (e) praxis.

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Middle latency evoked potentials include a series of evoked responses which encompass/include myogenic potentials (which translate the existence of sonomotor reflexes), and others which are clearly of neurogenic origin. Induced endpoint forces were typically consistent with behaviorally observed forces only when the ankle was immobilized. The image bioinformatics tool which results from the integration of the processing operations can be accessed at http://www.itqb.unl.pt:111/clsmip/. In the 1990s, a number of researchers in different fields showed that myofibroblasts are present during tissue repair or response to injury in a variety of other tissues, including the liver, kidney, and lung. It is argued that this particular example, founded on a hard-won clarification of rights and entitlements under the Constitution, may offer a more promising way forward than alternative approaches focused on legislative or administrative regulations. Meanwhile, extreme aseptic measures should be undertaken during its insertion to avoid maternal and possible neonatal infections. Results from the current study show an enhanced response of primary mouse embryonic fibroblasts (MEFs) to culture on nanofibrillar surfaces with more dramatic changes in cell spreading and reorganization of the cytoskeleton than previously observed for established cell lines.

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Orthopedic surgeons at our institution have noticed an increase in the number of infections due to Propionibacterium acnes, especially following operations on the shoulder. The synthesis of these molecules requires a proper protection of Cys residues, which is crucial to prevent side-reactions and also to achieve the correct Cys connectivity. Modulating the dehydration conditions of adefovir dipivoxil dihydrate to obtain different physical forms of anhydrate. Ultrasonography was demonstrated to be useful for pregnancy diagnosis and prediction of parturition. Adiposity phenotypes included dual-energy X-ray absorptiometry-assessed android fat mass, android:gynoid fat ratio and trunk:limb fat ratio, as well as body mass index. Early data also suggest benefit in the treatment of constipation. Finally, the test was applied to subjects with and without a family history of type 2 diabetes. When the going gets tough: Mental toughness and its relationship with behavioural perseverance.

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The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity. In general, the analyses of hearing thresholds and DPOAE data thus lead to the same conclusions concerning the state of hearing. These kinds of tumours are most frequently benign neurogen tumours in childhood. These data suggest that ocular, but not circulating ANF may contribute to regulate pupillary function. As the practice of pancreatic surgery evolves to encompass a wider array of clinical indications, incorporate increasingly complex technologies, and provide care to an aging population with many comorbid conditions, systematic assessment of quality and outcomes in an effort to improve the quality of care is imperative. In conclusion, the DDFT method may be useful in assisting neuroradiologists in estimating the white matter tracts. Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. The effects of analytical and experiential rumination on autobiographical memory specificity in individuals with a history of major depression. An advance notification letter increases participation in colorectal cancer screening. Finally, it was evaluated via electron micrographs, as well as immunohistochemical techniques at day 7, 14, and 28 after initial seeding.

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PLS gives the prediction error of 27.63 mg/dL with using unscrambler PLS-toolbox side effects of flagyl antibiotic in dogs while the traditional method gives an error of 72.15 mg/dL. Nonsteroidal antiinflammatory drugs (NSAIDs) induce apoptosis in a variety of cancer cells, including those of colon, prostate, breast and leukemia. The nonsurgical nature of patients with subarachnoid or intraparenchymal hemorrhage associated with mild traumatic brain injury. This is a good option for correcting the incontinence after major or total loss of lower lip muscles in patients with oral cancer. Supplementation of fructose in chemically defined protein-free medium enhances the in vitro development of bovine transgenic cloned embryos. Haemophilus influenzae strains of serotype a very rarely cause life-threatening infections. Modulation of intestinal muscle contraction by interleukin-9 (IL-9) or IL-9 neutralization: correlation with worm expulsion in murine nematode infections.

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In the present study we used ovariectomized (OVX) rats as a model of osteoporosis to investigate the effects of the antidepressant bupropion on the femoral bones. The aim of the present study was to investigate changes in PACAP38 concentrations in different brain areas following food or water deprivation in male and female rats. ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2. We have used gene expression analysis of 120 lung cancers followed by RNA interference, tumor-tissue microarray analysis, and functional analyses to systematically distinguish potential target molecules specifically expressed in cancer cells. TUBA1B was higher expressed in HCC tumor tissues than in adjacent nontumor tissues. Questionable validity of cardiac risk score on the basis of the NSABP B-31 model. In addition, several accessions, including Zu-0, showed marked acquired salt tolerance after exposure to moderate salt stress. On the basis of these X-ray crystallographic studies the detailed DFT investigation are performed.

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Solvent protection of the hammerhead ribozyme in the ground state: evidence for a cation-assisted conformational change leading to catalysis. Supporting Early Postpartum Attachment: Select a Birthing Environment that Clearly Supports the Infant-Parent Attachment Process. In the present setting, the carbohydrate metabolism is not impaired by GH therapy, but by the excessively increased fat mass. These results support a model in which the timing of FtsZ assembly is governed primarily through cell cycle-dependent changes in FtsZ polymerization kinetics and not simply via oscillations in the intracellular concentration of FtsZ. The basis for the conflicting results between transcription and CATase synthesis is discussed. In this study, we proposed a genetic adaptive filter to removing power-line interference. Association of red blood cell distribution width levels with severity of coronary artery disease in patients with non-ST elevation myocardial infarction. HIV infection had been known in both women for around ten years and both patients were cleocin t gel price not on antiretroviral therapy. Early profound jaundice following blunt hepatic trauma: resolution after lobectomy--case report. Moreover, care programs were in general not accepted by the professionals.

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ACTH causes an increase in the synthesis of both the mitochondrial and the microsomal forms of cytochrome P-450 involved in steroid hormone biosynthesis, as well as of the iron-sulfur protein involved in transferring electrons to the mitochondrial forms of cytochrome P-450, namely, adrenodoxin. Ceramide mediates differentiation, growth arrest, apoptosis, proliferation, cytokine biosynthesis and secretion, and a variety of other cellular functions. Our technique is based on the application of an alternating field across labeled giant unilamelar vesicles. The results support a mechanism whereby 14,15-leukotriene A4 is synthesized from 15-HPETE by a further enzymatic step carried out by the reticulocyte 15-lipoxygenase via hydrogen abstraction at C-10 and a redox cycle of the non-heme iron atom of the enzyme. Effect of smoking on lifestyle interventions to prevent diabetes. Using site-directed mutagenesis, we find that folding of wild-type myotrophin is initiated at the C-terminal repeats. A simultaneous operation was successfully performed on a 70-year-old man with recurrent aortic arch aneurysm and squamous cell carcinoma of the lung. This article reviews the known mechanisms by which Treponema interact with eukaryotic host cells and tissue proteins, and how these roxithromycin 150mg tab interactions may contribute to pathogenic diversity.

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Breakpoint setting requires integration of knowledge of the wild-type distribution of MICs, assessment of the pharmacokinetics/pharmacodynamics of the antibacterial, and study of the clinical outcome of infections when the antibacterial is used. A more permanent tolerogenic signal in the DMBA- but not solvent-treated lymph node resulted from an epidermal cell from DMBA-treated skin presenting antigen to suppressor cells. However there were no significant correlations between the platelet activation indices and the plasma levels of apolipoproteins, lipoproteins or lipids in either group. In mammals, these rhythms are generated by the circadian pacemaker located in the suprachiasmatic nucleus (SCN) of the hypothalamus. The study of these rumen paramphistomes, their infection, and public health importance remains unclear in India especially in the western part of state Uttar Pradesh (U.P.), Meerut, India, where the goat meat consumption is very high. A similar analysis using the medication possession ratio (MPR) as a measure of compliance was also performed in a subset of patients who had filled at least 2 warfarin prescriptions. The minimum alveolar concentration (MAC) of isoflurane is a quantitative trait because it varies continuously in a population. Critical roxithromycin brand nucleotides in the interaction of a LysR-type regulator with its target promoter region. This study is a review of 14 patients with paragangliomas between 1986 and 1996.

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All known strains of Bacillus gordonae can acquire, by spontaneous mutation, the ability to grow at the expense of acetamide as a source of carbon, nitrogen and energy. Down-regulation of regucalcin and prohibitin gene expression might contribute to the pathogenesis of liver cirrhosis. On the problem of diagnosis of incomplete perforation of the uterus in abortions. The relation between intention to conceive and symptoms during pregnancy: a preliminary report. An infant with multiple cavernous angiomas presenting with frequent epileptic seizures - detection of epileptic focus by magnetoencephalography. The endocannabinoid anandamide is an arachidonic acid derivative that is found in most tissues where it acts as levaquin type of drug an important signaling mediator in neurological, immune, cardiovascular, and other functions. This is a mechanism whereby chaperone uncapping from a subunit is coupled with the simultaneous assembly of the subunit into the pilus fiber. Amphotericin B deoxycholate is an alternative for persons who fail to respond to pentavalent antimony. Clinical trials were systematically collected (Medline, Cochrane and hand searches) reviewed and classified into evidence levels (1 to 5 according to the Oxford system).

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The mechanism and pattern of banding induced by restriction endonucleases in human chromosomes. Activation of a conditional c-MYC allele delayed progression through mitosis in pro-metaphase in a MAD2- and BubR1-dependent manner. Our results indicate that specific voltage sensors of the sodium channel play unique roles in gating, and suggest that movement of one voltage sensor, the S4 segment of domain 4, is at least a two-step process, each step coupled to a different gate. The degree and duration of hypertension are thought to be determinant factors of these abnormalities. Data stem from a cross-sectional study in a stratified, representative sample of 1483 recently deployed soldiers using standardized diagnostic interviews zithromax prices . These results support the notion that membrane electrical activity affects acetylcholine receptor expression by regulating the accumulation of the corresponding mRNAs.

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Visual loss occurred while responding to therapy for this immune-mediated disease. The method uses sharply focused ultrasound transducers of different focal lengths to induce a localized temperature elevation during a short exposure (1-20 seconds). The role of Moloney leukemia virus 10 in hepatitis B virus expression in hepatoma cells. Aerosol streptomycin treatment of advanced pulmonary tuberculosis in children. Phosphorylation of BIK1 and homologs after flg22 exposure was disrupted in transgenic Arabidopsis thaliana plants expressing FLS2(S938A) or FLS2(D997A) (a kinase catalytic site mutant), but was normally induced in FLS2(S938D) plants. The accuracy of stool immunoassay was estimated according to results obtained with other diagnostic methods. Therapeutic strategies to resuscitate the microcirculatory blood flow and to improve the functional capillar density are therefore essential to surmount the microcirculatory pathology and to avoid tissue hypoxia. Cell-free synthesis of membrane proteins should prove a valuable tool for the production of membrane proteins whose overexpression in heterologous systems is difficult. Vitamin C content, lipid peroxidation levels (conjugated dienes, CD) and the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were estimated in the oldest age group of males and females.

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