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Kofron (Clarithromycin)
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Kofron

Kofron is a macrolide antibiotic that fights bacteria in your body. Kofron is used to treat many different types of bacterial infections affecting the skin and respiratory system. Kofron is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

Other names for this medication:
Aeroxina, Biclar, Binoclar, Ciclinil, Clariston, Claritron, Clarocin, Claromac, Clathrocyn, Clatic, Claxid, Euromicina, Finasept, Fromilid, Glartin, Klabet, Klariger, Klarimax, Klarit, Klazidem, Kofron, Laromin, Lyoclar, Macrobid, Macromicina, Rolacin, Vikrol

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Biaxin, Myambutol, Cipro, Flagyl, Duricef, Amoxil, Sumycin, Keflex

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Also known as: Clarithromycin

Description

Kofron (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Kofron works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

Kofron Filmtab and Kofron Granules may be given with or without food.

Kofron XL Filmtab should be taken with food. Swallow Kofron XL Filmtab whole; do not chew, break or crush Kofron XL Filmtab.

Triple therapy: Kofron Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Kofron Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Kofron Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Kofron Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Kofron Filmtab/omeprazole. The recommended adult dosage is 500 mg Kofron Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Kofron are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Unidentified serogroups of enteropathogenic Escherichia coli (EPEC) associated with diarrhoea in infants in Londrina, Parana, Brazil. We analyzed data from a Web-based evaluation system containing all house staff and student evaluations of their attendings and internal medicine ward rotations at 2 university-affiliated teaching hospitals over a 2-year period (1999-2001). The purposes of this article were to examine the current state of the science surrounding the concept of distress and to propose a model of distress for patients with AL. Understanding astrocyte migration is fundamental to understanding the formation of the glial scar. Thirty-two patients underwent TTC arthrodesis with bulk femoral head allograft. Endothelins (ETs) have been shown to regulate astrocytic functions through ETB receptors.

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Antichlamydial antibodies and citric acid in patients with chronic prostatitis. Using competitive binding and quantitative light-microscope radioautography, we found that the median-eminence binding site, in contradistinction to the adrenal receptor, binds specifically the residue 4-10 region of the adrenocorticotropin molecule. The purpose of this study was to compare the cleocin suspension dosage clinical results of two cryosurgical methods in the treatment of neovascular glaucomas. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging. This was quite consistent for the annulus fibrosus in all regions and there were dramatic decreases in the lumbar nucleus pulposus in all adults compared with infants and children.

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