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Klazidem (Clarithromycin)

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Klazidem is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Althromicin, Biclar, Bicrolid, Binoclar, Ciclinil, Clacee, Clamycin, Clarimac, Clarimax, Clarimycin, Claritron, Clarix, Claromac, Claromycin, Claryl, Clasine, Clathrocyn, Claxid, Emimycin, Euromicina, Hecobac, Kalecin, Klariger, Klarit, Klarith, Klarithran, Klonacid, Laricid, Lekoklar, Lyoclar, Macladin, Onexid, Rodizim, Rolacin, Synclar, Uniklar, Xylar, Zeclar, Zeclaren

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Sumycin, Vantin, Cefixime, Terramycin, Noroxin, Rulide, Myambutol

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Also known as: Clarithromycin


Klazidem (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Klazidem works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Klazidem Filmtab and Klazidem Granules are recommended as the primary agents. Klazidem Filmtab and Klazidem Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Klazidem is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Klazidem therapy should continue if clinical response is observed. Klazidem can be discontinued when the patient is considered at low risk of disseminated infection.


If you overdose Klazidem and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Klazidem overdosage: nausea, vomiting, diarrhea, abdominal discomfort.


Store Klazidem XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Klazidem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Synchronized moving aperture radiation therapy (SMART): average tumour trajectory for lung patients. This study shows that the PCA3 urine test, when used as a reflex test, can improve the specificity in prostate cancer diagnosis and could prevent many unnecessary prostate biopsies. roxithromycin tab 150mg 10 Improving the Classification of Cirrhotic Liver by using Texture Features. Determining the prevalence of neuromuscular disorders for the general population is important to identify the scope of burden on society and enable comparisons with other health conditions. When the microbial compositions of four kefir grains were evaluated with culture-independent analyses, L. The fluorescence of serum proteins in diabetic patients with and without retinopathy. The separation of plant cells with ethylenediaminetetraacetic acid. Clinical and cardiographical observations on a derivative of pyrimido-pyrimidine (Persantin). Tissue mRNA concentrations of pro-inflammatory mediators and vascular remodelling molecules was assessed by real-time RT-PCR.

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Auditory brainstem implant (ABI) is an electroprosthetic device enabling sound sensations in deaf persons with a bilateral lesion of auditory nerves. Seven pairs of lambs fed colostrum and milk individually from seven scrapie-affected sheep (pre-clinical or clinical) presented with disease-associated prion protein, PrPd, in rectal lymphoid tissue at 4-5 months of age. While progress is being made in elucidating the clinical significance of recurrently mutated genes, layers of complexity have been added to our understanding of chronic lymphocytic leukemia pathogenesis in the guise of the molecular evolution and (sub)clonal architecture of the disease. Repeat interview survey of symptoms, disability, and receipt of care four years after index discharge. However, its findings helped support a subsequent Mozambican decision to conduct targeted distribution of long-lasting nets to the neediest populations in the provinces where the project was conducted. To investigate the incidence and risk factors of snoring in Boertala Mongolia Autonomous Prefecture of Xinjiang. Can a publicly funded home care system cost of flagyl without insurance successfully allocate service based on perceived need rather than socioeconomic status?.

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The use of two powerful classification techniques (boosting and SVM) is explored for the segmentation of white-matter lesions in the MRI scans of human brain. There is evidence that parents should be provided with such information when giving their informed consent to pyeloplasty. The clinical finding that decoronation can maintain or reestablish normal alveolar conditions is important for successful implant cleocin acne medication insertion later. Glutathione protects against myocardial ischemia-reperfusion injury by detoxifying peroxynitrite. These data show divergent effects of HAART on surrogate markers of apoptosis, when treatment is initiated sequentially with NRTIs first. Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome. The temporal relationship between cyclin A accumulation and the onset of DNA replication was analyzed in detail. To accomplish this task, a biophysical model that links ribosome binding site (RBS) DNA sequence to toggle switch bistability was first developed by integrating a stochastic model with RBS design method.

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