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Klarigen (Clarithromycin)

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Klarigen is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat. Klarigen is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)].

Other names for this medication:
Bacterfin, Bicrolid, Ciclinil, Clabact, Clarimac, Clarimycin, Claripen, Clarosip, Clathrocyn, Claxid, Egelif, Eracid, Finasept, Fromilid, Glartin, Karin, Klabion, Lyoclar, Macladin, Macrol, Macromicina, Mononaxy, Nutabact, Quedox, Uniklar

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Biaxin, Sumycin, Myambutol, Ilosone, Avelox, Zithromax, Terramycin, Cipro

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Also known as: Clarithromycin


Klarigen (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Klarigen works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


Klarigen Filmtab and Klarigen Granules may be given with or without food.

Klarigen XL Filmtab should be taken with food. Swallow Klarigen XL Filmtab whole; do not chew, break or crush Klarigen XL Filmtab.

Triple therapy: Klarigen Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Klarigen Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Klarigen Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Klarigen Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Klarigen Filmtab/omeprazole. The recommended adult dosage is 500 mg Klarigen Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.


If you overdose Klarigen and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Klarigen overdosage: nausea, vomiting, diarrhea, abdominal discomfort.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Klarigen are:

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Plastic prostheses of the pavilion of the ear and of the nasal pyramid. Very interestingly, most transcripts encoding key enzymes involved in flavonoid biosynthesis were highly expressed regardless of starvation, while transcripts encoding laccase, the last rate-limiting enzyme of lignifications, exhibited very low expression abundance in all three samples. Effect of Curculigo orchioides rhizomes on sexual behaviour of male rats. Immunohistochemistry was used to detect the expression of ABCG2, P-gp, and breast cancer stem cells(BCSCs) markers(CD44 and CD24) in breast cancer tissue before chemotherapy and residual breast cancer tissue after chemotherapy. Hemoglobinopathies are priority genetic diseases for prevention programs. In the remainder of the patients, the CR melatonin was studied on a clinical basis. A synthetic gene for somatomedin C, a human growth factor, has been assembled by a single ligation of 23 oligodeoxyribonucleotides, which were chemically synthesized by an improved solid phase phosphotriester method. Incidence of Intestinal Nematodes and Protozoa in Dogs in the Montreal District.

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Exogenously transplanted PGCs migrated toward the anterior region of the embryo and the embryonic gonads when they were transplanted into the subgerminal cavity, but not into the posterior marginal zone, in Eyal-Giladi and Kochav stage X embryos. However it is clear that eradication of HIV is not achievable with existing anti-HIV drugs and in spite of the major advances there remain many challenges in the clinical management of HIV-infected individuals. Subjects stood on a force platform as electrical stimuli were applied to the posterior tibial nerve when the center of pressure (COP) was either 1.6 standard deviations anterior (COP(ant)) or posterior (COP(post)) to the mean baseline COP signal. However, these changes are not global and likely occur in a cell type-specific or possibly a gap junction-specific manner. Here, we share a very useful and simple front-end surveying methodology-lectin blotting-for proteomic analysis of glycosylation patterns-the most abundant posttranslational modification in extracellular signaling.Lectin blotting is an effective biochemical technique based on lectin-glycan interactions. To identify relationships between 2D:4D ratio and behaviours in preschool children which constitute possible precursors of developmental psychopathology. Cytokine production by the BiP-responsive clones was determined by analysis of post-stimulation supernatants by ELISA. Thus, ST has a dual function both as a PO inhibitor to counter host immune reactions and also as an antibiotic to exclude microbial competitors from the insect cadaver.

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To describe trends in hospitalisation for sport-related concussion. Age-specific norms were established for height, weight, and BMI, and compared to US reference data by z-score analysis, while mean heights and weights by age were compared to published national Russian data. Further objectives were to investigate whether changes in sensory perception are correlated with pain intensity and tactile acuity or motor imagery performance. Predentin was found to be positive for both antibodies and the reaction ceased in the calcification front. All subjects were infected with a virulent H pylori strain (vacA s1/m1, cagA positive genotype). We present our experience with the use of a DIEP flap reconstruction following extensive mastectomy. Although PCR is probably more sensitive than are conventional microscopy-based methods for diagnosing Pneumocystis carinii pneumonia, the specificity is uncertain, because P.

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Streptococcus pneumoniae remains the most common cause of pneumonia, and pneumococcal antibiotic resistance is increasing. Biosynthesis of tetracycline by 5-hydroxy-tetracycline-producing cultures of Streptomyces rimosus. These loci regulate stem cells by intrinsic (cell autonomous) and/or extrinsic mechanisms and dictate stem-cell fate decisions. The zfAHR2-MO but not the zfCYP1A-MO inhibited zfCYP1A mRNA expression, indicating the specificities of these morpholinos. Dog liver microsomes have at least three different enzymes that are capable of the deacylation of amides, N-arylhydroxamic acids and carboxylesters, the acyltransfer of N-arylhydroxamic acids and the N-acetylation of arylamines. To analyze the mechanism of IRES-mediated initiation, binding of IRES RNA to salt-washed ribosomes in the absence of translation factors was studied. Herein, we introduce a new and highly effective method to enhance the photostability of one of the commonly used fluorescent dyes, rhodamine 6G (R6G). Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma. The radial distribution function of water oxygen and hydrogen atoms clarifies the effect of concentration on the structure and clustering of water. Detection of viral RNA in tissues with visna virus and viral DNA with hepatitis B virus are illustrated, and potential applications of this technique in virology and other disciplines are discussed.

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Varying patterns of BMI increase in sex and birth cohorts of Korean adults. DDP kills cancer cells primarily by creating intrastrand and interstrand DNA cross-links, which block DNA replication. We report that recessive STGD can rarely be inherited from only one unaffected carrier parent in a non-mendelian manner. Combining and comparing data from multiple species is challenging because of noise in expression data, the different synchronization and scoring methods used, and the need to determine an accurate set of homologs. Somatic stimuli exciting spinothalamic projections to thalamic neurons in cat and monkey. When the disorder is genetic or the cause is unknown and dystonia is the sole feature, the disease is called primary or idiopathic, conversely secondary dystonia (SD) may be caused by various brain insults. These enzymes are involved in the regulation of inflammatory processes in tuberculosis. Yttrium 90-labeled ibritumomab tiuxetan radioimmunotherapy produces high response rates and durable remissions in patients with previously treated B-cell lymphoma. Health status ten years after pediatric liver transplantation--looking beyond the graft.

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Our results indicate that exposure to DG, or induction of DG production by treatment of B cells with exogenous phospholipase C, results in depolarization and increased I-A antigen expression similar to that induced by anti-receptor antibody and specific antigen. A restriction fragment length polymorphism, detected between B10.P (KpDp) and B10.F(14R) (KbDp) and between B10 (KbDb) and B10.F(13R) (KpDb), has enabled us to map the lambda 3a sequence to the D or Tla region. It is not clear whether this has changed the relation between social factors and depression in older people. Isolated mitral valve insufficiency in comparison with mitral-tricuspid insufficiency: various mechanisms of compensating for the defect and functional status of the myocardium. We hypothesized that NF-kappaB is differentially activated in different regions of the gastrointestinal tract during endotoxemia.

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These findings suggest that Prox1 plays important roles in conferring and maintaining the characteristics of LECs by modulating multiple signaling cascades and that integrin alpha9 may function as a key regulator of lymphangiogenesis acting downstream of Prox1. Lipid metabolism disorders were proposed to mediate numerous cell membrane alterations in various forms of hypertension. The present study has demonstrated that following partial meniscectomy, treatment with hyaluronan can enhance meniscal regeneration and may inhibit articular cartilage degeneration as long as six months post surgery. The value of dynamic cardiomyoplasty has been brought into question by the disappointing results produced by slow contraction-relaxation cycle and possibly degeneration of the latissimus dorsi muscle (LD) secondary to temporary tenotomy and chronic daily electrical stimulation. Through the analyses of genetic divergences and neighbor-joining (NJ) phylogenetic relationships between the species of ticks, our results show that COI and 16S are reliable in discriminating species of ticks and the 18S could discriminate ticks at the genera level. After a bout of moderate intensity exercise, a meal with a high-fat/low-carbohydrate ratio had a less favorable metabolic impact than an isoenergetic, isoproteic low-fat/high-carbohydrate meal. Due to the possible spontaneous resolution, we suggest an initial conservative treatment in cases of sub-ILM hemorrhage related to SBS. Furthermore, on this cell line, representative of the Th2 group of helper cells, DEX had little effect on the proliferation induced by exogenous IL-4 but completely inhibited the growth-promoting effects of IL-2.

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When this fraction was loaded onto protein A-Sepharose two distinct peaks were always generated in a pH gradient (pH 8.0-2.1). We investigated the incidence of APOL1 variants in young African Americans with hypertension or FSGS and a family history of ESRD by conducting a case-control study of 93 pediatric and young adult African Americans with hypertension or FSGS to determine the association with APOL1 risk variants, G1, and G2 using custom-made TaqMan-based allelic discrimination assays. Block-and-release experiments with cytochalasin A and the localization of actin in germlings by indirect immunofluorescence showed that actin participated in septum formation. Applications of capillary electrophoresis to molecular recognition and analysis of in-capillary enzyme-mediated transformations. Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. These agents inhibit the secretion of the cytokines thought to be involved in the pathogenesis of ICD. We investigated the hypothesis of the protective effect of saffron on lethal cardiac arrhythmias induced by heart ischemia-reperfusion in rat. A slide for the direct determination of the corrected relative Q-T duration, heart rate, and percent-amplitudes of electrocardiographic deflections.

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Cell motility, proliferation, cell invasion, and colony formation assays were performed according to the standard protocols. A total of fifty-five composite soil samples were collected from four CCA-treated wood structures of approximately one year in age. The cuticular hydrocarbons of ants are composed of molecules of varying chain lengths from three structural classes, n-alkanes, methyl-branched alkanes and n-alkenes. Therefore, we examined the association of the quantity and intensity of physical activity with CHD risk and the impact of other coronary risk factors. Chromatin immunoprecipitation assays on pure cultures of human intestinal mucosal endothelial cells undergoing EndoMT were performed with antibodies to specific histone modifications and RNA polymerase II.

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To determine levels of perceived risk of HIV infection and the determinants of these perceptions among commercial farm workers. Age dependence of tumor genetics in unfavorable neuroblastoma: arrayCGH profiles of 34 consecutive cases, using a Swedish 25-year neuroblastoma cohort for validation. Images of perpetrators in surveillance video footage are often used as evidence in court. Developing protocols for recombinant adeno-associated virus-mediated gene therapy in space. Kinetics of dephosphorylation of eIF-2(alpha P) and reutilization of mRNA.

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Different small nuclear ribonucleoprotein particles are involved in different steps of splicing complex formation. The colony forming unit (CFU) counts and species diversity was further reduced in the air directly after the filters. The self-organizing map (SOM) is an unsupervised learning method as well as a type of nonlinear principal component analysis that forms a topologically ordered mapping from the high-dimensional floxin tablet data space to a low-dimensional representation space. Creatinine clearance had the advantage of a distribution suitable for parametric statistical tests. It was hypothesized a priori that OLIG2 and OLIG1 were associated with OCD regardless of the presence of comorbid Tourette disorder (TD), but not with TD alone.

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Some of the genes identified as showing overexpression in the cancer cells, particularly those encoding secreted or membrane-bound flagyl cause yeast infection proteins, could be potential biomarkers for tumors or targets for rational therapeutics that are dependent on VHL status. We describe our experience with a surgical technique using the multiple fire Endo-GIA-30-3.5 stapler to control the vascular pedicles during radical cystectomy. To study the consistency of reporting of abnormal rectal biopsy specimens, especially in the differentiation of inflammatory bowel disease from other causes of abnormality. These results suggest that MCS modulates the pathways from the posterior insula and orbitofrontal cortex to the posterior thalamus to upregulate the pain threshold and pathways from the posterior insula to the caudal ACC to control emotional perception. We then demonstrate the postrecording image processing techniques for 3D visualization. Severe masticatory muscle spasms interfered with feeding, but were successfully treated with botulinum toxin.

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The strains under study proved to be atoxigenic, hemolysis-positive and phage resistant. In serum-free medium, increasing the seeding density yielded a linear increase in coverage of the substrate area but decreased cell alignment. All patients who were at risk for ICU-acquired infection admitted from January 1999 to December 2002 were followed from admission to discharge. Budesonide or prednisone in combination with ursodeoxycholic acid in primary sclerosing cholangitis: a randomized double-blind pilot study. Bilateral osteochondrosis dissecans in the supratrochlear foramen. Acclimatization to hypoxia increases the hypoxic ventilatory response (HVR) in mammals. Oxidation products arising from the action of monoamine oxidase B on 1-methyl-4-benzyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn-antigen.

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High intracellular concentrations of ATDs were observed in macrophages within 30 min of administration of nanoparticles. High level of exogenous glutamate caused marked decrease of cell viability in mouse cerebellar granule cell cultures, which could be partly warded off by 20 microM PD150606. Different additives have been used to prolong brachial plexus block. This paper stresses the advantage of pooling data from different registries in studies of uncommon specific malformations and infrequent characteristics. Finally, CRH treatment of IVB cell lines has been linked to CREB-mediated gene expression as determined via the PathDetect CREB trans-reporting system. Determination of the effective hydrodynamic radii of small molecules by viscometry. Quantitative lung perfusion following single lung transplantation. Evaluation and treatment of posterolateral instability of the knee.

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Ultrathin Te nanowires can be oxidized easily with cost of flagyl oral various final morphologies, which are core-shell structures in contact with air, amorphous nanoparticles and nanoplatelets in ethanol, and large square flakes in water. The main directions of correction of digestive disorders and its results. Due to their frequent front-line contact with the public, family physicians (GPs) have the potential to play an important role in the primary prevention of cancer. The biodistribution of 123I-ANP was studied in green vervet monkeys by gamma scintigraphy and in rats by dissection and gamma counting. Drug-eluting stents versus coronary artery bypass grafting in patients with diabetes mellitus. The low base-rate of suicide and ethical concerns of studying suicidal people in controlled trials of medications or psychotherapy are the two most important obstacles for progress in suicide research. Microscopic examination revealed that the tumor was a moderately differentiated tubular adenocarcinoma, which displayed invasion to the pancreas with lymph node metastasis up to the level 3 lymph node.

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A 71-year-old woman on chronic therapy with mianserine and amantadine was scheduled to undergo abdominal hysterectomy under spinal anesthesia. The observed polarized photoluminescence spectra can be explained by the calculated electron spin-dependent optical transition probabilities based on the local-spin density approximation. We obtained pharmacy and hospital sales data for 1985-2001 from IMS Canada for all ACE inhibitors (Anatomical Therapeutic Category code C09A0) and for the 3 largest provinces (i.e., British Columbia, Quebec, Ontario). Synthesis, characterization, antimicrobial activity and mechanism of a novel hydroxyapatite whisker/nano zinc oxide biomaterial. The intermediate oncologic outcomes of laparoscopic radical nephrectomy for advanced renal cell carcinoma are comparable to those historically achieved with open radical nephrectomy. Many nursing decisions involve questions regarding the effectiveness of interventions, best evaluated by RCTs. Recommendations for the health monitoring of mouse, rat, hamster, guineapig and rabbit breeding colonies. Further, functional enrichment analysis revealed that RRM-containing gene products are mainly involved in biological functions such as mRNA splicing and its regulation. Evaluation of the emergency diagnostic and therapeutic measures for the diagnosis of ACS before and after the introduction of the ACS care concept, was carried out retrospectively for the years 2004 (group 1) and 2005 (group 2) by electronic data processing of the records stored in the emergency medical services documentaion system (NADOK). The authors hypothesized that this decline has been largest for boys, since boys have a higher risk of fetal and neonatal death.

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The main objective of the paper is to provide a better understanding of the machinery and processing in noroxin dosage the central nervous system (CNS) that relates to stepping. The standardized actions of pregnancy monitoring are performed in the background while practitioners use the technology to support the local culture of praise to motherhood and the family. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. Investigation of histological giant sections and morphometry to confirm a new application of minimally invasive surgery. Following first-trimester miscarriage, subfertile women who conceived after assisted reproduction had higher stress and anxiety-depression levels, and experienced more traumatic impact from the event, than those after natural conception.

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