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Klabax

Klabax is a prescription medicine used to treat the symptoms of many different bacterial infections, including stomach ulcers and Helicobacter pylori. Klabax may be used alone or with other medications. Klabax is an antibiotic.

Other names for this medication:
Aeroxina, Althromicin, Biclar, Biotclarcin, Cidoclar, Clabact, Clacee, Clacina, Clamycin, Clarimac, Claripen, Claritron, Clarocin, Clarogen, Claromac, Claron, Claryl, Clarytas, Egelif, Eliben, Eracid, Euromicina, Fromilid, Hecobac, Helimox, Kalecin, Klabax, Klarifor, Klariger, Klarit, Klarith, Klarithrin, Klaritpharma, Klazidem, Klonacid, Kofron, Laromin, Lekoklar, Preclar, Quedox, Rodizim, Taclar, Vikrol, Zeclar

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Also known as: Clarithromycin

Description

Klabax (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Klabax works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Klabax Filmtab and Klabax Granules are recommended as the primary agents. Klabax Filmtab and Klabax Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Klabax is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Klabax therapy should continue if clinical response is observed. Klabax can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

If you overdose Klabax and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Klabax overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store Klabax XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Klabax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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However, the molecular mechanisms of these effects are not completely understood. A systematic approach to these cases should help to achieve treatment success. Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. When patients were classified on the basis of AFR tertiles, Cochran-Armitage analysis demonstrated that the highest tertile of AFR level showed an increased odds ratio for the prevalence of CVD. Toward the development of a lupus interactive navigator to facilitate patients and their health care providers in the management of lupus: results of web-based surveys. Specificity of the antibody was determined by immunoblot analysis with purified bovine cardiac troponin. Two Japanese patients with severe lupus nephritis (WHO class IV-G) who were administered long-term intermittent MZR pulse therapy, and in whom pre- and post-treatment renal biopsies were reported.

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Young infants prefer to look at a person who previously spoke their native language. In vitro evaluation of tablets containing alkaline phosphatase from bovine intestine (BIAP) was the first step in the development. Symptoms of this adult onset disease are progressive weakness of the hip and shoulder girdles, as well as a distinctive dysarthric pattern of speech. Colorectal mass lesions masquerading as chronic inflammatory bowel disease on mucosal biopsy. A diagnosis of atrophic pattern is indicative of low numbers of neutrophils. However, among children with VWD or hemophilia, the rate of does levaquin cover sinus infection delayed hemorrhage is substantially higher, especially in older children. The known role of nitric oxide and pro-inflammatory cytokines in the activation of host defenses against infection prompted us to examine the ability of certain AGPs to enhance non-specific resistance in mice to Listeria monocytogenes and influenza infections as well as to stimulate the production of pro-inflammatory cytokines in mouse splenocytes, human PBMCs, and human U937 histiocytic lymphoma cells. Novel vaccine candidates based on molecular technology such as recombinant proteins, peptides, viruslike particles, naked DNA, and recombinant viruses are being explored.

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