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Grinazole (Metronidazole)

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Grinazole is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

Other names for this medication:
Amodis, Anamet, Anazol, Aristogyl, Bemetrazole, Diazole, Dumozol, Entizol, Giardyl, Metral, Metrin, Metris, Metrobac, Metrodal, Metrofusin, Metronid, Metronidazol, Metrosil, Metrozol, Metsina, Monizole, Nidazole, Nizole, Patryl, Pharmaflex, Protozol, Rosaced, Taremis, Trichomonacid, Tricofin, Venogyl

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Also known as: Metronidazole


Grinazole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Grinazole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Pregnant patients should not be treated during the first trimester. In pregnant patients in whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation


Single oral doses of Grinazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Grinazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Grinazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store Grinazole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Grinazole out of the reach of children and away from pets.

Side effects

The most common side effects associated with Grinazole are:

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Serum concentrations of IDO and TTS in 61 patients with CKD and 16 healthy volunteers were tested by ELISA. When feasible, surgical resection plays a fundamental role in effecting a cure. Stereotactic aspiration biopsy of nonpalpable nodules of the breast. Seven patients were alive at follow-up, three of whom had stents inserted for malignancy and four as a result of complications following transplantation. A flow cytometry protocol was developed comprising single-tube CD45, CD14, CD16, CD64, CD163, CD143 analysis with appropriately matched isotype controls. The results of this study suggest the potential use of a solid SMEDDS formulation for the delivery of poorly water-soluble drugs, such as sirolimus, through oral administration. Dermatan sulfate (DS) is well-known for its anticoagulant activity through binding to heparin cofactor II to enhance antithrombin action. Cranial computerized tomography and electroencephalography were carried out in addition to baseline investigations (toxoplasmosis, other, rubella, cytomegalovirus, and herpes simplex virus serology, serum lactate, pyruvate, amino acid screen, thyroid function tests, and chromosome analysis). These experimental observations report novel physiological features in the cell biology of SCs and refer to an intrinsic heterogeneity within which their stemness may reside. The behavior of brain tissue in cases of arteriovenous malformations (AVMs) is a matter of debate.

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These results suggest that the scale is an effective and feasible screening tool for HIV-associated neurocognitive disorders in poorer regions of China with fewer well-educated residents. Application of virulence studies to the problems of BCG immunization. We report a case of a first branchial groove anomaly presented as an infected cyst in an 11-month-old child. Molecular domestication--more than a sporadic episode in evolution. Three of these (PAb122, PAb240, CM-1) also immunolabelled stabilized wild type p53 in cell cultures and elicited a consistent, characteristic labelling pattern in a subset of tumours. When individual behaviour matters noroxin pills side effects : homogeneous and network models in epidemiology. In this report, mtrIII was localized to a 2.1-kbp SalI/XbaI DNA fragment. The present investigation describes the interaction of eleven structurally related benzaldehydes with guinea pig liver aldehyde oxidase and bovine milk xanthine oxidase, since they have similar substrate specificity to human molybdenum hydroxylases.

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With morning administration insulin activity is greater in the first 0-12 h, while with evening administration the activity is greater in the 12-24 h period following dosing. Alopecia totalis and isolated lichen planus of the nails are uncommon subtypes of common dermatologic disorders. Evolving complex dynamics in electronic models of genetic networks. However, an increase of clinically relevant, databased information is promising. Some countries totally ban PGD, while the others keep close track of the new applications.

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Photodynamic therapy (PDT) was studied in the treatment of a variety of solid malignant tumors. It is argued that when the space is partitioned into atomic regions the consideration of these distributions may provide a first step toward an orbital invariant treatment of resonant structures. Changes in fiber composition of soleus muscle during rat hindlimb omnicef dosing uti suspension. Comparative pharmacology of N-substituted tertiary and quaternary amino esters of acetic and propionic acid. AFI-based myocardial deformation parameters including segmental tissue velocity, strain, and strain rate as well as biventricular global strain and strain rate were measured from raw scan-line data obtained from 28 normal fetuses (20-38, median 28 weeks of gestation). Intra-abdominal hypertension and the abdominal compartment syndrome. Fibrinogen is a key component of the blood coagulation system and plays important, diverse roles in several relevant pathologies such as thrombosis, hemorrhage, and cancer. A literature review of experiences with phenol intoxications reveals the advantages of PEG application.

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Total necrosis of 1 flap occurred and 1 patient required reoperation on the first postoperative day for revision of the anastomoses. The thiol inhibitor MAG-283 had IC50 values of 480 nM and 3 nM against human interstitial collagenase (MMP-1) and MMP-2, respectively, and KI value of 2.2 nM against MMP-9. First is the mapping of a 3D level-set solver onto a commodity graphics card (GPU). Obese cats consistently had excessive fat around the heart especially if they also had a large amount of falciform fat. Flow cytometric immunophenotyping of serous effusions and peritoneal washings: comparison with immunocytochemistry and morphological findings. As women with hirsutism reported poorer HRQoL compared to the normal population, social support may be a factor to consider in clinical practice.

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We employed the method recommended by the Cochrane Collaboration to perform a meta-analysis of randomized controlled trials (RCTs) of gabexate in the prevention of post-ERCP pancreatitis (PEP) including three RCTs conducted in Italy and one in China. SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling. It was also found that overexpression of Rab7-Q67L and, to a lesser extent, Rab7-WT increased the amount of proteolytically processed, mature gp100. In this review we summarize the available data on the genetics of ghrelin axis in humans. In this paper, we extend this analysis by focussing on how small autocatalytic networks are likely to be when they first emerge. Seasonal and spatial distribution of 4-nonylphenol and 4-tert-octylphenol in the sediment of Kaohsiung Harbor, Taiwan. Use of the periodontal ligament injection in dental care of the patient with hemophilia--a clinical evaluation. Injuries include punctures, crushes, lacerations and avulsions of flaps. Vitamin E attenuates homocysteine cefpodoxime vantin tablet 200 mg and cholesterol induced damage in rat aorta.

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Amplification of chromosome 5p correlates with increased expression of Skp2 in HPV-immortalized keratinocytes. Effect of right coronary artery occlusion during percutaneous transluminal coronary angioplasty on right ventricular performance. Wide-angle light scattering was not found to contribute significantly to the changes in ageing nor did reduced retinal illumination, as reproduced by reduced pupil diameter or viewing through a neutral density filter. Four functional MBL2 alterations in codons 52, 54, 57 and in biaxin class of drug the promoter at position c.1-290 are correlated with significantly lowered MBL serum levels. The mitotic spindle of vascular plants is assembled and maintained by processes that remain poorly explored at a molecular level. In this review I describe in vitro assays that can be used to assess the activity of agents that affect angiogenesis. A flexible, transparent, and skin-like biocompatible graphene electrical field stimulator was placed directly onto the cortical brain, and a noncontact electric field was applied at a specific local blood vessel. SAR patients were identified by history, skinprick test, specific IgE and positive nasal allergen challenge. The pilot plant study comprised the construction and monitoring of a new vertically moving biofilm system (VMBS) for treating municipal wastewater.

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