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Flagolin (Metronidazole)

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Flagolin is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Aldezol, Amevan, Amotein, Amrizole, Anabact, Anaeromet, Anerozol, Colpofilin, Diazole, Emedal, Farnat, Fladex, Fladystin, Flagystatine, Flazol, Metrofusin, Metronidazolum, Metrovax, Metryl, Metsina, Nipazol, Onida, Protogyl, Rosaced, Rosalox, Rovamet, Stomorgyl, Tismazol, Trichazole, Trichostatic, Unigyl, Varizil, Venogyl, Vertisal, Zobacide

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Also known as: Metronidazole


Flagolin (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Flagolin is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Use Generic Flagolin preparation for 5-10 days or if it is needed can take it longer. It is better to take Generic Flagolin 2-3 times a day at the same time on empty stomach. Do not stop taking Generic Flagolin suddenly.


Single oral doses of Flagolin, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Flagolin has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Flagolin overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store Flagolin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Flagolin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Flagolin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Interaction with Alcohol. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole.

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A visualization tool, the hexaMplot, is able to show the interrelations of gene expressions in normal-disease-drug samples in three-color microarray data. Here, using a model system of crystalline graphite, we show from first-principles calculations, new details in the behaviour of vacancy and interstitial defects. As in Drosophila, Botra transcripts are spliced in a sex-specific manner so that only females encode a functional polypeptide of 422 amino acids, whereas males encode presumably nonfunctional peptide(s). Then, we focus on recent data relating how differences in genotypic and phenotypic diversity within PFP communities can be attributed to geographic location, climate, soil type, soil management regime, and interactions with other soil microorganisms and host plants. This might indicate a possibility to find markers for genetic selection of individuals with a well-developed immune system without negative effects on milk productivity. These abnormalities are due to genetic and environmental factors. Blood pool agents remain in the intravascular space for a longer time period. Combined search for anti-beta2-glycoprotein I and anticardiolipin antibodies in antiphospholipid syndrome: contribution to diagnosis. Cortical activation associated with the experience of auditory hallucinations and perception of human speech in schizophrenia: a PET correlation study.

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Trials of compounds to enhance trap catches of Glossina palpalis palpalis in Liberia. In a 71-year-old man, after induction of anesthesia and neuromuscular blockade, facemask ventilation was moderately difficult. The goal of this pilot study was to compare regular insulin administered by continuous rate infusion (CRI) to an approach using insulin glargine and regular insulin administered intermittently. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. The use of decision modeling for estimating drug cost before product launch is a powerful technique to ensure value for money. The median age was 52 years (range: 38 to 63 years), with ECOG Performance Status (PS) 0-1, grade 0-1 weight loss, and grade 0-1 pain. Both experiments were double-blind double-dummy repeated measures. When the mode amplitude becomes large, the lattice melts (disorders), in accord with the Lindemann criterion for melting in two dimensions. Chest radiography remains the imaging modality of choice for initial examinations because it offers simplicity, low cost, and a large amount of information. However, our knowledge of racial disparities in neonatal mortality associated with low birth weight and short gestation is relatively limited.

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Androgenic activity of the adrenal cortex of Cricetomys gambianus. Furthermore, the prolongation of CMCT alone does not seem to suffice to differentiate between various types of autosomal dominant cerebellar ataxias. There has been no sign of recurrence for 6 months after the chemotherapy. This work demonstrates that the shear stiffness of liver tissue increases systematically with the extent of hepatic fibrosis, as measured by histology. In the case of microenvironment-mediated resistance this can involve an intrinsic response, including the co-option of pre-existing structural elements and signaling networks, or an acquired response of the tumor stroma following the therapeutic insult.

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Three months after Hurricane Hugo, 5,687 school-aged children were surveyed about their experiences and reactions to the hurricane. Some epidemiological features of leukemia in the Buffalo area of New York. The rats in these four groups were then killed at different time points to observe the kinetic change of selenoproteins. History of ischemic heart disease significantly increases LOS, but does not increase morbidity after LC. Massive suprachoroidal hemorrhage was demonstrated on echography and confirmed on histopathologic examination in all eyes. In practice, when a primer pair fails to amplify in a multiplex PCR for some individuals, singleplex PCR is often employed as a supplement to amplify the primer pair. Zinc regulatory factor (ZRF) is a zinc-dependent MRE-binding protein that was originally detected in HeLa cell nuclear extracts using the most proximal MRE of the human MT-IIA gene (hMREa) as a probe.

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Fluorescein angiography confirms the presence of vasculitis without any retinal oedema or areas of non-perfusion, which may sometimes accompany the condition. It is concluded that cell deformability and/or spreading ability might be an important determinant of binding strength, but the factors governing binding efficiency remained incompletely understood. Our results suggest that, as with walking and running gait, small amounts of visual information about swimmers can be used for recognition, and so raise the possibility that specific training may be able to improve team-mate classification in water-polo, particularly in newly formed teams. Serum drug concentrations and/or tissue accumulation are related to the development of nephrotoxicity, and individualised pharmacokinetic monitoring may decrease rates of nephrotoxicity. To evaluate the structural and functional outcomes of the use of a modified suture-bridge technique to prevent a marginal dog-ear deformity compared with a conventional suture-bridge method in rotator cuff repair. donovani promastigotes to avoid MAPK and NF-kappaB activation in naive macrophages may be part of the strategy evolved by this parasite to evade innate immune responses. Phylogenies of the two genes constructed by the neighbour-joining method were created and compared to a concatenated tree of 16S rDNA, hsp65, sodA and rpoB genes. A new method for kinetic studies of both PGHS activities in the course of cyclooxygenase as well as peroxidase reactions and also preincubation with hydroperoxides is suggested. Guideline-conform management by regional and interregional care concepts. Genome destabilization enhancement of irradiated in vitro human somatic cells under ascorbic acid effect is due to its co-mutagenic properties.

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The levels of Pb, Zn, Cu and Cd in the surface soil of Shangbacun village in the lower reach of the river were found as high as 257.762, 350.235, 5.083 and 186.901 mg x kg(-1) respectively, which were relatively higher than those of the background values of soil 1.03, 1.75, 16.9 and 3.7 times respectively, and the result on the soil profiles showed that the contaminations have infiltrated into lower layer soil, ecological environment was harmed severely. We determined the extent to which partial crop loads and receiver filling and emptying rules (i.e. Which arises in some cells through changes in genes (DNA-level: geneamplification, mutation and rearrangement) or their expression (RNA- and protein-level), and gives these cells a growth advantage in comparison to the surrounding cells. Additional procaspase expression occurred in astrocytes and microglial cells at different times following ischemia. These behaviors showed a very low intraclass correlation coefficient (0.02 - 0.05) and low kappa (-0.08 - 0.21) in the test-retest design, which suggest a poor reliability of these measures. The buildup factor: effect of scatter on absolute volume determination. The interpretation of lumbar computer tomograms depends on the qualitative and quantitative assessment of the contents of the spinal canal and of its surrounding structures.

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However, the impact of implant support varied with the location of implant in this theoretical study. Revascularization strategy for proximal LAD disease: left internal mammary to LAD artery still rules the roost. The GluR1 subunit of the AMPA receptor is located at postsynaptic sites within the nucleus of the solitary tract, particularly in dendritic spines, which are important sites for synaptic plasticity. Hereditary breast cancer: pathobiology, clinical translation, and potential for targeted cancer therapeutics. The diagnostic and prognostic significance of SCUBE1 levels in Crimean-Congo hemorrhagic fever.

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L1CAM was up-regulated in osteosarcoma cell lines and primary tumor samples and the expression level of L1CAM were negatively correlated with miR-503 levels in osteosarcoma tissues. This case illustrates that protein S deficiency is a factor that should be considered in cases of retinal vein occlusion, particularly in young patients. Fifty patients (31 females and 19 males, age 36-66 yr) were randomly assigned to the treatment and control groups. In this study we determined the effects of palm vitamin E and alpha-tocopherol on bone metabolism. Although barium esophagography is advantageous in demonstration of the sinus tract in PSF, US and CT are also capable of showing the sinus tract. Comparisons were made between preoperative clinical data and the clinical data at 1, 6, and 10 years after surgery. Whereas all three solvents studied give rise to a sponge (L3) phase in the MO-water system, this phase was only found when MPD was added to the PT-water system. The genes and molecular pathways underpinning these checkpoints overlap with those involved in tumor suppression. It mediates cell-to-cell interaction by binding to integrin alphavbeta3 via the RGD motif of its second EGF domain. The approach does not suffer approximation error from limited sweep width of the main magnetic field and explicitly incorporates the variability in signal-to-noise ratio versus strength of magnetic field gradient.

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Takotsubo cardiomyopathy (TCM), otherwise cardiomyopathy,apical ballooning syndrome or broken heart syndrome is a reversible cardiomyopathy, predominantly occurs in post-menopausal women and commonly due to emotional or physical stress. Guidelines for molecular karyotyping in constitutional genetic diagnosis. An infectious Shiga toxin (Stx) 2e-converting bacteriophage (phiP27) was isolated from Stx2e-producing Escherichia coli ONT:H(-) isolate 2771/97 originating from a patient with diarrhea. To systematically summarize the available clinical data on the QT interval and to offer improved recommendations for the use of QT-prolonging medications. Spinal meningiomas in younger patients have a worse prognosis than similar tumors in older patients. No other parameter demonstrated a statistically significant difference. This study from a hypersaline Bahamian lagoon details the response of a benthic cyanobacterial mat to disturbance by Hurricane Frances, a category-4 storm. The factors responsible for the bleeding time prolongation were investigated.

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Molecular cloning of flounder Xp18, a newly identified highly conserved protein mainly expressed in the ovary. Intracellular drug delivery nanocarriers of glutathione-responsive degradable block copolymers having pendant disulfide linkages. We then examined the roles of CD44-HA interaction in bone metastasis using 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis. Two meta-theories, coherence and correspondence theories, have been used to provide alternative views and prompt significant debate to advance the science. Often undiagnosed in travelers with acute nonspecific febrile illness, gastrointestinal, abdominal, pulmonary, neurologic, or cutaneous signs and symptoms, rickettsial diseases are transmitted in particular geographic and ecologic settings by ticks, fleas, chiggers, and lice. Colour vision defects among doctors and diabetic patients: implications for diagnosis and management. Matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry (MS) for the identification of mycobacteria from MBBacT ALERT 3D liquid cultures and Lowenstein-Jensen (LJ) solid cultures. At present there is no medicine allowing an effective treatment of RNA-based virus infections.

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Evaluate radiographical and clinical characteristics of patients undergoing a selective thoracic fusion (STF) for Lenke 1C curves. A report on accrual rates for elderly and minority-ethnicity cancer patients to clinical trials of the American College of Surgeons Oncology Group. 6-Phosphofructo-2-kinase (PFK-2)/fructose-2,6-bisphosphatase (FBPase-2) catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, a potent stimulator of glycolysis. Adjuvant effect of high-frequency hyperthermia of the abdominal cavity on the course of transplanted leukemia in AKR mice. These mice also presented low circulating bacterial counts and diminished systemic inflammatory response. The tumor/uterine AP diameter ratio and minimal tumor-free margin/uterine AP diameter ratio seem to be the best objective measurement techniques to predict deep myometrial invasion. This method of sampling has been compared with the direct injection of an aliquot of headspace gas and shows biaxin antibiotic and alcohol an enrichment factor of approximately 100 over a 1 ml gas injection for organosulphur gases such as dimethyldisulphide. Thus, separate reactive species are involved in the oxidation of methionine and nitration of Tyr99 whose relative concentrations are determined by solution conditions. In each experiment, the matching stimuli were either physically identical, semantically related, or semantically unrelated.

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The main types of surgical procedures involving the lumbar spine are briefly reviewed, focusing on CT and MRI appearance of normal sequelae of early or late complications and the recurrence of the lesion that necessitated the first procedure. Based on this character, an EMN phase shift extraction algorithm is proposed. Results from this trial will provide guidance regarding key social environmental factors that can be manipulated to support motivational processes conducive to positive health behaviour change and optimal functioning in patients with Rheumatoid Arthritis. Selective processing of emotional information in obsessive compulsive disorder. Application of paper chromatography and electrophoresis to the assay of pharmaceutical products.

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SP-induces NK1R endocytosis by a beta-arrestin-dependent mechanism, which also involves the GTPases dynamin and Rab5a. Neuromodulation of the cingulum for neuropathic pain after spinal cord injury. The mentioned increase in the concentration of steroids was disconnected with the elevation affecting the concentration of gonadotropins, but likely due to their discharge from ovaries. Perspective on liver regeneration by bone marrow-derived stem cells-a scientific realization or a paradox. This article reviews the biology of the inherited peripheral neuropathies, delineates major phenotypic features of the CMT subtypes, and suggest strategies for focusing genetic testing. This distortion, absent in the high temperature crystalline structure of NaCl type, is a remnant of the atomic arrangement in the A7 low temperature crystalline phase. The selectivity ratios for the inhibition of the tumor-associated over the cytosolic isozymes were in the range of 107-955 for the most selective such inhibitors. Future research needs to evaluate the types and quantity of physical activity needed for optimal protection from falls and identify which populations will benefit most from exercise.

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Recent evidence suggests that wild-type p53 prevents cell-cycle progression after DNA damage, which may provide a sufficient period for the cells to repair the genetic lesions that may otherwise lead to cell death or cellular transformation. For diagnostic assessment, only the percentage of elements suggestive for malignancy in each lesion was used. The pseudodisaccharide mycothiol is present in millimolar levels as the dominant thiol in most species of Actinomycetales. Biological activity of Bacillus thuringiensis strains against larvae of the blowfly Chrysomya putoria (Wiedemann) (Diptera: Calliphoridae). Results also indicated variations in game playing in relation to the extent of handicap in the infant. The morphologic and immune-histochemical findings confirmed the diagnosis. A temperature-based feedback control system for electromagnetic phased-array hyperthermia: theory and simulation.

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Evidence should be interpreted in a manner consistent with the analytic goal. For F-actin networks in the absence of alpha-actinin or for F-actin/alpha-actinin networks at high temperatures, strain hardening appears only at very short time scales. These results correspond in both cases to partial localization of the counterions within a layer that is thinner than the effective Debye screening length. This review provides some evidence for the effectiveness of CBT for treatment of acute stress disorder following mild TBI and CBT combined with neurorehabilitation for targeting general anxiety symptomatology in people with mild to moderate TBI. Our strategy is to use a required Web-based course to establish a knowledge base upon which specific training during clinical rotations build skills.

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Plant hormone-assisted early family selection in Pinus densiflora via a retrospective approach. We start by can you drink alcohol with levaquin reviewing the different types of simulation strategies and algorithms that are currently implemented. A longitudinal cohort of Finnish twin pairs (FinnTwin12) was analyzed using self-reported height at 11-12, 14, 17 years and measured stature at adult age (21-24 years). Irradiation could change the 3D-distribution of abl and bcr genes in the interphase nuclei of IM-9 cell and accelerate them to draw near each other. Statistical optimization of process parameters on biohydrogen production from glucose by Clostridium sp. We have observed six hypersensitivity reactions to the mafenide that occurred following several weeks of continuous use of the drug. This suggests that the activity seen in earlier micronucleus assays may have arisen by a mechanism not involving direct DNA interaction. Preparation and characterization of a laboratory scale selenomethionine-enriched bread.

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Ehrlichia species in Rhipicephalus sanguineus ticks in Cameroon cleocin 600 mg tablet . UDP-GlcNAc (UDP-N-acetylglucosamine) and UDP-GlcA (UDP-glucuronic acid) were oxidized by periodate in the ribose ring and utilized as inhibitors for hyaluronate synthase in membrane fractions from the B6 cell line and in cell cultures of B6 cells and human fibrosarcoma HT 1080. Sterol-regulated proteolysis of a membrane-bound transcription factor provides a novel mechanism by which transcription can be regulated by membrane lipids. The effect of cervical synpathectomy and equal irritation of the trigeminal nerve on the serotonin level in the aqueous humor of the rabbit eye. Deaths related to fires--protection of risk groups can be improved. We did not perform meta-analysis as we only included one RCT in the review. Exercise Hemodynamics and Quality of Life after Aortic Valve Replacement for Aortic Stenosis in the Elderly Using the Hancock II Bioprosthesis.

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Computer aided detection of pulmonary embolism with tobogganing and mutiple instance classification in CT pulmonary angiography. Myelosuppression required dose reductions in eight patients and discontinuation of therapy due to repeated treatment delays in two patients. Various initiatives, such as pharmacist interventions, therapeutic interchanges, and obtaining appropriate patient parameters, can be implemented in the practice setting to ensure the appropriate use of oral anticoagulants and improved patient outcomes. This observation also provides a new direction for further investigation into the pathophysiological relevance of Langerhans cells and other antigen-presenting cells in the development of atopic diseases. Tumor specific CTL were generated in vitro by co-culture of mature DC with autologous T lymphocytes.

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Therefore, uncertainty as to whether cardiac dilatation or hypertrophy is present or which predominates is usually related to the inability to assess these states critically at the time of autopsy when the ordinary pathological methods are used. Strategies for reversing the trend towards subfertility in dairy zithromax dose poids cattle. Intraventricular ganglioglioma prognosis and hydrocephalus: the largest case series and systematic literature review. These data indicate that there may be several regulatory pathways and molecules involved in the antigen-silencing process which may be related to the state of differentiation of the tumor cell and may affect the outcome of antitumor vaccine immunotherapies. Study of the sensitizing properties of tetanus toxoids in experiment. Kinetic data identified the association between the two DNA half-sites as the rate-limiting step of the assay. Alkaline deoxyribonuclease induced with diterpene ester TPA and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. The results show that after adjusting for selection bias day-care centers have a positive impact for a specific part of the population.

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Enterococci were isolated from various clinical samples and also from fecal specimens of colonized patients at the time of admission, after 48 h and after 5 days of admission. Collagen detachment did not modulate lactoferrin secretion but strongly induced casein secretion, with detachment on day 6 (after formation of cell sheets) inducing casein secretion to 3 micrograms/ml medium, which was 2-3-fold higher than for cells on collagen detached on day 2 (prior to cell spreading to form sheets), and ten-fold higher than for cells grown on collagen not detached. Glycemia, ketonemia, and brain enzymes of ketone body utilization in suckling and adult rats undernourished from intrauterine life. Here, we investigated molecular mechanisms involved in this process, focusing on conditions that are associated with obesity, that is, hyperinsulinemia and induction what type of medicine is levaquin of hypoxia. Legal demands for structured interviews after coercive measures are not followed.

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Human reproductive physiology displays characteristic patterns that can be viewed as mechanisms that help optimize reproductive effort in the face of environmental energetic constraints. In a health maintenance organization that mails letters to women recommending that they schedule mammograms, we conducted a randomized trial to evaluate simple methods of increasing the use of screening mammography. Specifically, early life traumatic events, occurring during a period of neuronal plasticity, appear to permanently render neuroendocrine stress response systems supersensitive. SKAP-55(-/-) T cells retain ADAP expression cipro 500 dosing yet show defects in beta1 and beta2 integrin adhesion, leukocyte function-associated antigen 1 (LFA-1) clustering, production of the cytokines interleukin-2 and gamma interferon, and proliferation. In addition, the SG strain was not detected in the eggs of chickens immunized with our mixture. Cardiorespiratory responses to incremental exercise in patients with asbestos-related pleural thickening and normal or slightly abnormal lung function. The factors most consistently associated with poor nutrition included impaired function, dementia, swallowing/chewing difficulties, poor oral intake, and older age. The authors use their experience with this study to encourage more involvement by nursing programs in projects such as this, thus enhancing minority opportunities in nursing research.

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For the treatment of an acute ischemic stroke, the early use of thrombolytic agents can reduce the degree of brain damage while improving functional outcomes. This manuscript describes in detail the development of the gestational dating protocol, intensive ultrasound training involved, ultrasound capacity building, and ultrasound quality control program. There was an inhibition of AChE activity with carbofuran, and a toxic effect shown by an increase in TBARS levels counteracted by increases in GST and CAT activities which protected the larvae. The smoothing complicates identification of multiple simultaneous bioelectrical events. Tuberculin Studies: XIV Comparative Activity of Purified Protein Derived Tuberculins Prepared from Different Strains of Tubercule Bacilli. Blood samples were collected at admission from 40 neonates with suspected infection. While the pathophysiology of radiculopathy and myelopathy is better understood, the source of neck pain remains somewhat controversial.

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