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Fladex (Metronidazole)

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Fladex eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Aldezol, Amobin, Amotein, Anabact, Aristogyl, Bemetrazole, Collazole, Dequazol, Efloran, Elyzol, Fladystin, Flagenase, Florazole, Ginerella, Metazole, Metco, Metrodal, Metrofusin, Metsina, Molazol, Nidagyl, Orvagil, Otrozol, Polibiotic, Rosaced, Rozacrme, Suanatem, Tolbin, Trogyl, Vagilen, Varizil

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Biaxin, Zithromax, Myambutol, Cleocin, Cipro, Cefixime

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Also known as: Metronidazole


Fladex (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Fladex is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Pregnant patients should not be treated during the first trimester. In pregnant patients in whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation


Single oral doses of Fladex, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Fladex has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Fladex overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Fladex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


As a rule, the usual duration of therapy with i.v Metronidazole or other imidazole derivatives is usually less than 10 days. This period may only be exceeded in individual cases after a very strict benefit-risk assessment. Only in the rarest possible case should the treatment be repeated. Limiting the duration of treatment is necessary because damage to human germ cells cannot be excluded.

Intensive or prolonged Metronidazole therapy should be conducted only under conditions of close surveillance for clinical and biological effects and under specialist direction. If prolonged therapy is required, the physician should bear in mind the possibility of peripheral neuropathy or leucopenia. Both effects are usually reversible.

In case of prolonged treatment, occurrence of undesirable effects such as paraesthesia, ataxia, dizziness and convulsive crises should be checked. High dose regimes have been associated with transient epileptiform seizures.

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Risk taking and its influence on metabolic control: a study of adult clients with diabetes. Lethal and inhibitory effects of steep pulsed electric field on tumor-bearing BALB/c mice. Two deep wells were drilled to tap mineral water within the past decades. The purpose of this study was to establish normal values of plasma BTG during pregnancy, labor and puerperium. Mean linear acceleration measured over a season of matches was similar to the mean linear accelerations previously reported for youth, high school, and collegiate American football players but lower than that for female youth soccer players. To this end, preoperative CT images were processed with specialised computer software. Attempts at clinical measurement of pulmonary arterial pressure. High-energy chirped- and divided-pulse Sagnac femtosecond fiber amplifier.

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We have analyzed the SARS data and the effect of the control measure in HongKong, based on a spatial Monte-Carlo model (SEIR) with susceptibles, exposed(latent), infective, and recovered. Even the very low levels of E1A products in Ad5 E1A-immortalized cells are sufficient for this reduction. Is agreement between reviewers any greater than would be expected by chance alone?. Immunoprecipitation analysis demonstrated that Rnd3 and NICD physically interacted, and that down-regulation of Rnd3 attenuated NICD protein ubiquitination. To determine whether polymorphonuclear neutrophils (PMNs) are required for diarrhea for Salmonella colitis, we infected kanamycin-pretreated interleukin 8R (IL-8R) mutant mice and controls, both with nonmutant Slc11a1 (Nramp1, ItyR). The activity of different mitogen-activated protein kinases (MAPKs) in IL-31-stimulated BEAS-2B cells was assessed by Western blot. The maltose transport complex of E.coli is one of the most well-characterized members of the ATP-Binding Cassette (ABC) protein superfamily. During metamorphic climax, many larval RBCs expressed TUNEL-positive reactions in the spleen, suggesting that the larval RBCs were specifically removed from the spleen during metamorphosis. Strategies to facilitate recruitment will need to be added to future protocols.

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ABC proteins represent the largest superfamily of transmembrane proteins in prokaryotes and eukaryotes, performing diverse functions from ion transport by the cystic fibrosis transmembrane regulator to multiple drug efflux by the P-glycoprotein transporter and sugar transport by the maltose transporter. Alcoholics with eating disorders: prevalence and clinical course. 2) Although the two patients were referred at very different ages, the clinical presentations raise the possibility of phenotypic variability for the same mutation. the differences among the cleft sides of unilateral cleft lip and palate (UCLP) patients, non-cleft sides of the same UCLP patients and well matched control patients in the root development and position of permanent upper central incisors and 2. Numerous clinical trials have demonstrated increases in trabecular and cortical BMD (trabecular more than cortical) in men and women, and reduction in vertebral and nonvertebral fractures in postmenopausal women.

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Technical observations on the method for the assay of substances inhibiting MAO. Here we apply the phage display technique to identify some new signature motifs, (F/W)XXL(F/W) and FXXLY (where F is phenylalanine, W is tryptophan, L is leucine, Y is tyrosine, and X is any amino acid) that can influence the interaction between AR and AR coregulators. Drug levels in the tumor interstitium appeared crucial as intracellular levels of free or liposome-associated doxorubicin were not increased by TNF-alpha. Factors influencing the development of oral cancer include regulatory factors of the cell cycle, the inherited vulnerability of the genetic code of certain proteins and the presence of HPV infection with an oncogenic genotype. To present a probable clinical course of lumbar disc herniation with alkaptonuria, a rare metabolic disease. W7 and W13 caused phase delays longer than 10 hr at CT 6 and caused a phase advance of about 5 hr at CT 10 when present at a 200-microM concentration. In this single-phase, single-center, prospective, randomized control trial, the patients were randomized to receive either shankha bhasma purified by method A or by method B. Coherent supercontinuum generation in a silicon photonic wire in the telecommunication wavelength range. This work aims to study the gene expression profiles associated with Zinc or Cadmium exposure and to identify genes involved in metal tolerance in these two metallicolous Mesorhizobium strains of interest for mine phytostabilization purposes. Strategies used for intensive insulin therapy of critically ill patients and differences of approach according to medical condition are reviewed.

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Patients with ovarian carcinoma were found to have significantly higher SCL than patients with benign ovarian lesions. Predicting chronic leukaemias from assessment of complete peripheral blood counts. Reasoning about relocation or aging in place in very old age is a complex and ambivalent matter. Ileus after the use of loperamide how long after taking flagyl can i drink alcohol in a child with acute diarrhea. Clinical practice shows that early treatment almost always succeeds in limiting the severity of stuttering to a mild form. We further examine the characteristics of these trematodes that make them useful models for the analysis of larval parasite-host relationships. Is there a gender difference in coping, perceived disability and handicap in patients with noise-induced hearing loss?. Rising hospital admissions and mortality from hepatocellular carcinoma in Portugal.

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Despite intensive research, PE is still one of the leading causes of maternal mortality, although reliable screening tests or effective treatments of this disease have yet to be proposed. If the ancient acupuncture verses could be understood thoroughly, the clinical practice could be better guided and its effects could be improved. Lipoprotein lipase (LPL), a pivotal enzyme in lipoprotein metabolism, catalyzes the hydrolysis of triglycerides of very low-density lipoproteins and chylomicrons. Oligodendrocytes from nerve also matured faster than nerve derived astrocytes, in contrast, however, they attained a greater morphological complexity than nerve astrocytes. In the present study, we have used PKA mutant mice (R(AB) transgenic mice), which have reduced PKA activity in neurons within the hippocampus, to explore the role of temporal spacing of synaptic stimulation in regulating the PKA-dependence of LTP. The purpose of the present study was to identify gene polymorphisms that confer susceptibility to restenosis after bare-metal stenting of coronary arteries, and thereby to predict the genetic risk for this condition. Finally, uric acid pretreatment enhanced significantly the survival rate in the SSI mice. Bone is the main target organ for the storage of several toxic metals, including uranium. In twenty-one children with myelomeningocele and progressive scoliosis, treatment of scoliosis was attempted with a Boston type underarm brace.

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