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Danoflox (Ofloxacin)
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Danoflox

Danoflox is used for treating mild to moderate infections caused by certain bacteria. Danoflox is a fluoroquinolone antibiotic. It kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Other names for this medication:
Albact, Bactocin, Bioquil, Biravid, Danoflox, Docofloxacine, Dolocep, Drovid, Ecuflox, Ermofan, Ethiflox, Evaflox, Ofloxacin

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Ilosone, Chloromycetin, Rulide, Biaxin, Vantin, Suprax

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Also known as: Ofloxacin

Description

Danoflox is a prescription medication used to treat certain bacterial infections including bronchitis, pneumonia, and infections of the skin, bladder, urinary tract, reproductive organs, and prostate (a male reproductive gland). Danoflox belongs to a group of drugs called fluoroquinolone antibiotics. It works by killing bacterial cells that cause infection.

This medication comes in oral tablet form and is usually taken 2 times a day. Common side effects of Danoflox include nausea, insomnia, headache, dizziness, diarrhea, vomiting, rash, and itching. Danoflox can also cause blurred vision, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how Danoflox affects you. This brand name product is no longer available in the United States. Generic alternatives are available.

Dosage

Take Generic Danoflox with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent crystals from forming in the urine. You may take Generic Danoflox with or without food, but take it at the same time each day. Generic Danoflox will not treat a viral infection such as the common cold or flu. Generic Danoflox can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Generic Danoflox. Do not stop taking Generic Danoflox suddenly.

Overdose

Information on overdosage with Danoflox is limited. One incident of accidental overdosage has been reported. In this case, an adult female received 3 grams of Danoflox intravenously over 45 minutes. A blood sample obtained 15 minutes after the completion of the infusion revealed an Danoflox level of 39.3 µg/mL. In 7 h, the level had fallen to 16.2 µg/mL, and by 24 h to 2.7 µg/mL. During the infusion, the patient developed drowsiness, nausea, dizziness, hot and cold flushes, subjective facial swelling and numbness, slurring of speech, and mild to moderate disorientation. All complaints except the dizziness subsided within 1 h after discontinuation of the infusion. The dizziness, most bothersome while standing, resolved in approximately 9 h. Laboratory testing reportedly revealed no clinically significant changes in routine parameters in this patient.

In the event of an acute overdose, the stomach should be emptied. The patient should be observed and appropriate hydration maintained. Danoflox is not efficiently removed by hemodialysis or peritoneal dialysis.

Storage

Store Danoflox below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Store in a tightly closed container. Do not store in the bathroom. Keep Danoflox out of the reach of children and away from pets.

Side effects

The most common side effects associated with Danoflox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Fluoroquinolones, including Danoflox (ofloxacin) , are associated with an increased risk of tendinitis and tendon rupture in all ages. This adverse reaction most frequently involves the Achilles tendon, and rupture of the Achilles tendon may require surgical repair. Tendinitis and tendon rupture in the rotator cuff (the shoulder), the hand, the biceps, the thumb, and other tendons have also been reported. The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. Factors, in addition to age and corticosteroid use, that may independently increase the risk of tendon rupture include strenuous physical activity, renal failure, and previous tendon disorders such as rheumatoid arthritis. Tendinitis and tendon rupture have been reported in patients taking fluoroquinolones who do not have the above risk factors. Tendon rupture can occur during or after completion of therapy; cases occurring up to several months after completion of therapy have been reported. Danoflox (ofloxacin) should be discontinued if the patient experiences pain, swelling, inflammation or rupture of a tendon. Patients should be advised to rest at the first sign of tendinitis or tendon rupture, and to contact their healthcare provider regarding changing to a non-quinolone antimicrobial drug.

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