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Corsabutol (Ethambutol)
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Corsabutol

Corsabutol is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii. It is taken by mouth.

Other names for this medication:
Althocin, Amiobutols, Bacbutol, Combutol, Corsabutol, Dexambutol, Ebutol, Esanbutol, Etambutol, Etapiam, Etham, Ethambutol, Ethambutolo, Ethambutolum, Etibi, Fiambutol, Macox, Miambutol, Mycobutol, Niazitol, Oributol, Pulna, Rifafour, Rimstar, Santibi, Sural, Themibutol, Tibitol, Tibutol, Turresis

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Flagyl, Noroxin, Cefixime, Cleocin, Ceftin, Chloromycetin, Cipro, Levaquin

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Also known as: Ethambutol

Description

Corsabutol (EMB, E) is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii. It is taken by mouth.

Common side effects include problems with vision, joint pain, nausea, headaches, and feeling tired. Other side effects include liver problems and allergic reactions. It is not recommended in people with optic neuritis, significant kidney problems, or under the age of five. Use during pregnancy or breastfeeding has not been found to cause harm. In the United States the FDA has raised concerns about eye issues in the baby if used during pregnancy. Corsabutol is believed to work by interfering with the bacteria's metabolism.

Dosage

Initial Treatment: In patients who have not received previous antituberculous therapy, administer Corsabutol 15 mg/kg (7 mg/ lb) of body weight, as a single oral dose once every 24 hours. In the more recent studies, isoniazid has been administered concurrently in a single, daily, oral dose.

Retreatment: In patients who have received previous antituberculous therapy, administer Corsabutol 25 mg/kg (11 mg/lb) of body weight, as a single oral dose once every 24 hours. Concurrently administer at least one other antituberculous drug to which the organisms have been demonstrated to be susceptible by appropriate in-vitro tests. Suitable drugs usually consist of those not previously used in the treatment of the patient. After 60 days of Corsabutol administration, decrease the dose to 15 mg/kg (7mg/ lb) of body weight, and administer as a single oral dose once every 24 hours.

During the period when a patient is on a daily dose of 25 mg/kg, monthly eye examinations are advised.

Overdose

If you overdose Generic Corsabutol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature (20 to 25 degrees C [68 to 77 degrees F]) away from light and moisture. Keep this and all medicines out of the reach of children.

Side effects

The most common side effects associated with Corsabutol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Lab tests, including liver and kidney function, complete blood cell counts, and vision, may be performed while you use Corsabutol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Corsabutol should not be used in CHILDREN younger than 13 years old; safety and effectiveness in these children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Corsabutol while you are pregnant. Corsabutol is found in breast milk. If you are or will be breast-feeding while you use Corsabutol, check with your doctor. Discuss any possible risks to your baby.

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