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Clarogen (Clarithromycin)
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Clarogen

Clarogen is an antibiotic used to treat various types of infections. It is effective in most infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against a bacteria known as H. pylori, which is associated with peptic ulcer disease.

Other names for this medication:
Ciclinil, Clabact, Clabel, Clacee, Clacine, Clarimac, Clarimycin, Claripen, Claritron, Claritt, Clariwin, Clarocin, Claromac, Clarosip, Clasine, Clathrocyn, Cleanomisin, Derizic, Eracid, Fromilid, Geromycin, Gervaken, Glartin, Hecobac, Heliclar, Helozym, Kailasa, Kalecin, Karid, Klabax, Klabet, Klarigen, Klarimax, Klarit, Klarithrin, Klazidem, Kleromicin, Klonacid, Krobicin, Macrobid, Macrol, Mononaxy, Preclar, Rocin, Rodizim, Rolacin, Synclar, Taclar

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Also known as: Clarithromycin

Description

Clarogen (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Clarogen works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Clarogen Filmtab and Clarogen Granules are recommended as the primary agents. Clarogen Filmtab and Clarogen Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Clarogen is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Clarogen therapy should continue if clinical response is observed. Clarogen can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

If you overdose Clarogen and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Clarogen overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Clarogen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Discontinue immediately if hepatitis or severe hypersensitivity reactions occurs. Severe renal impairment. Proarrhythmic conditions (eg, hypokalemia, hypomagnesemia, bradycardia); avoid. Myasthenia gravis. History of porphyria; avoid concomitant ranitidine bismuth citrate. Elderly. Pregnancy (Cat.C): usually not recommended. Nursing mothers.

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Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells. An improved understanding of the regulation of mitochondrial quality may provide a strategy for treating aging-related diseases by targeting mitochondria and mitophagy pathways. A suite of nonlinear optimization methods is outlined for semiempirical parameter development based on integrated evolutionary (genetic) and direction set minimization algorithms. Radiation-hypersensitive cancer patients do not manifest protein expression abnormalities in components of the nonhomologous end-joining (NHEJ) pathway. Improving outcomes in cancer patients on oral anti-cancer medications using a novel mobile phone-based intervention: study design of a randomized controlled trial. Hydranencephaly: a rare cause of delayed developmental milestones. A screening was carried out on six strains of the fungus in order to select the most active. Our data suggest that functional visual deficits might precede background retinopathy and that the involvement of foveal function is early and very frequent in diabetic patients, even if they have normal visual acuity. This study suggests that ECHORBC could be transfused to patients safely and efficiently.

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Twenty-four patients with facial paralysis received neuromuscular facial retraining between April 1999 and April 2001. In this study, we analysed the polymorphic variants of IL-1alpha (C-T transition at position -889), IL-1beta (C-T transition at position -511) and IL-1 receptor antagonist (Ra) (86-bp repeated sequence in intron 2) in 1131 subjects (453 females and 678 males) from Northern and Central Italy, including 134 centenarians, to evaluate whether IL-1 cluster alleles might be differently represented in people selected for longevity. We have shown that this property depends on the ability of the Rop moiety to fold and dimerize. Myxofibroma of the left cardiac auricle with the clinical picture of a mitral lesion. The challenge of tissue engineering blood vessels with the mechanical properties of native vessels, and with the anti-thrombotic properties required is immense. rebaudiana leaves and Agrobacterium rhizogenes (C58C1) after infection, which were further verified by PCR detection of rolB and rolC genes.

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Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids. The simulation results are in a good agreement with the experimental data obtained within a wide range of doses. Evaluation of the groundwater quality feasibility zones for irrigational purposes through GIS in Omalur Taluk, Salem District, South India. The model is a cellular automaton approximation of a reaction-diffusion process in which matrix metalloproteinases represent the activator, inhibitors of matrix metalloproteinases represent the inhibitor, and growth factors serve as a substrate. Matrices loaded with rhGDF-5 induced ectopic cartilaginous and osseous tissue when implanted in subcutaneous or intramuscular sites. Cell type-specific gene expression was detected: Purkinje cells in the cerebellum and Sertoli cells in testis. This paper reviews the pathological and bioengineering considerations in the selection of cardiac prosthetic valves and the management of patients who have received these devices. A total of 405 firefighters of the Community of Madrid participated in the study. Ergothioneine is a secreted antioxidant in Mycobacterium smegmatis. Clinical features of 32 patients with cutaneous small vessel vasculitis.

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The peak flow velocity, velocity time-integral in diastole and systole, and basal blood flow in the proximal part of the left anterior descending artery, were assessed by transthoracic Doppler echocardiography 1 day before, and 5 days after, cardiac surgery in 17 children with ventricular and atrioventricular septal defects whose mean age at surgery was 6 months. Significant levels of immunologic specificity were observed with cAC10-3 by comparing antigen positive versus negative cell lines and binding versus non-binding control ADCs. Thirty-two patients whose supine diastolic blood pressure was between 95 ans 115 mmHg without known secondary hypertension, unstable diabetes, cardiac, renal or hepatic failure, hypokalemia, coronary artery disease or stroke in the previous year. Calculations based on variations in iron requirements and bioavailability of dietary iron. Thus, it is possible to distinguish intraoperatively between traumatic and degenerative lesions. To investigate the impact of targeted treatment on direct medical costs of patients with advanced non-small cell lung cancer (NSCLC). One developed bursitis and drainage and a fourth persisted in a patient with systemic lupus erythematosus. The results of this nationwide survey, in connection with two previous field and clinical studies, indicate that more importance must be given to oral hygiene education together with increased facilities for treatment. Microcephalic osteodysplastic primordial dwarfism is a rare disease characterized by unique clinical appearance and specific radiographic findings, and distinctive brain abnormalities. Of all the causes of bacterial endocarditis, HACEK group consisting of Haemophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella Kingae are rare causative agents.

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In vitro protein kinase C phosphorylation sites of placental lipocortin. Types or groups of staphylococci predominating during the particular period at the maternity department were evaluated according to survival rates in the colonized subjects. Inositol trisphosphate mobilizes internal calcium stores and this is accompanied, and enhanced, by an influx of calcium from the external milieu. In the USA this problem has been tackled by promoting a national education programme involving extensive use of television together with written guidelines for management. Transurethral resection of the lesion was performed, and both pathological and immunohistochemical findings confirmed a diagnosis of endocervicosis/ endosalpingiosis. This comparative study was designed to investigate the RHAMM expression patterns in endometrial carcinoma. Nanometer TiO2 was also active on the surface of green pepper under natural sunlight both inside and outside of plastic greenhouse. Using APPI, at an LC flow rate of 200 microL/min, it is possible to obtain analyte signal intensities 8 times as high as those obtainable with a commercially available corona discharge-atmospheric pressure chemical ionization source.

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Many studies have evaluated factors related to lumbar multifidus (MF) muscle atrophy. However, motor-evoked potentials recorded from lower limb muscles are not detectable in patients with severe cervical myelopathy. Kinematic and kinetic gait parameters do not predict the TUG performance in stroke patients. Microstructure and physical properties varied with the treatment condition. On the other hand, increasing the overall copolymer concentration at fixed W0 gives rise to a significant decrease of the micelle size in terms of the micellar aggregation number. Pharmacokinetics and absorption of foscarnet after intravenous and oral administration to patients with human immunodeficiency virus.

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A dramatic shift in the transmembrane topology of a viral envelope glycoprotein accompanies hepatitis B viral morphogenesis. Blacks were most likely to end initiation of any use and regular use with marijuana, whereas alcohol and tobacco were the most common end stage drugs for whites. Left ventricle hypertrophy is induced by a number of stimuli and can lead to cardio-myopathy and heart failure. Total SCCA in the circulation comprises 2 nearly identical, approximately 45 kDa proteins, SCCA1 and SCCA2. Real-time reverse transcriptase-polymerase chain reaction and Western blots were performed subsequently to evaluate the validity of molecules identified by 0.12K cDNA array composed of matrix metalloproteinase, oncogenes and cell cycle related genes. The clinical manifestations can be somewhat variable depending upon which gene is involved, and where the mutation occurs. Clinical research helps elucidate the role of tumor necrosis factor-alpha in the pathogenesis of T1-mediated immune disorders: use of targeted immunotherapeutics as pathogenic probes. Synthesis, characterization, computational calculation and biological studies of some 2,6-diaryl-1-(prop-2-yn-1-yl)piperidin-4-one oxime derivatives.

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Two-year carcinogenicity study on three aromatic epoxy resins applied cutaneously to CF1 mice. Normal values of total 12-lead QRS voltage and its significance in diagnosing left ventricular hypertrophy. Interventional catheterization in pediatric congenital and acquired heart disease. This cascade affects the cell wall integrity but the phenotype of Pkc1 mutants suggests additional targets which have not yet been identified. Postural effects on F wave parameters in lumbosacral root compression and canal stenosis. Although the patterns are conserved in different visual environments, they do not prevent the cell from signaling the strength of its response to a particular stimulus, which is expressed in the number of spikes contained in each coding epoch. Computer simulations were used to study the gel transition occurring in colloidal systems with short-range attractions. Experiment 2 ruled out the possibility that the effects observed in Experiment 1 resulted from perceptual learning. As a result management of pain, as well as depression, and other physical and mental symptoms, may not be adequately addressed in the primary care setting. Revascularisation resynchronises left ventricular wall motion by restoring the normal activation response to stress, thereby reducing total isovolumic time and normalising peak cardiac output response to stress.

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Experimental and molecular genetic analysis of the impact of pyrethroid and non-pyrethroid insecticide impregnated bednets for mosquito control in an area of pyrethroid resistance. We provide the first evidence that hemokinin-1 plays norfloxacin tablet brand name a crucial pro-inflammatory role in the lung by increasing inflammatory cell activities, and might also be a specific regulator of lymphocyte functions. The proposed system can be self-adapted to certain changes in the operating microwave frequency and can operate stably under certain fluctuations in the input optical power and frequency. Oxidative stress plays an important role in the pathogenesis of early brain injury (EBI) following subarachnoid hemorrhage (SAH). Interest in these compounds prompted us to explore palladium catalysis as an alternative to the existing methods for their preparation. The notes of 30 university students with learning disabilities (LD) and 30 nondisabled university students were compared on the number of cued and noncued information units recorded and the number and type of abbreviations used. Effectiveness of mouthguards in reducing neurocognitive deficits following sports-related cerebral concussion. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro.

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Detection of formaldehyde in textiles by chromotropic acid method. A comparison of ankle fixation between two kinds of low-temperature plastic anterior ankle foot orthoses. Biomineralization toolkit: the importance of sample generic of vantin cleaning prior to the characterization of biomineral proteomes. Interactions of viruses in Cowpea: effects on growth and yield parameters. A European network of NICUs using a standardised methodology is required to determine the feasibility and reliability of different risk-adjusted measured of HAI rates. Despite an intrinsically equal ability to tolerate chemotherapy, older adolescents and young adults frequently receive lower dose intensities than do younger patients, and at times less than in older patients. Group 1 patients received no preoperative or postoperative chest physiotherapy.

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