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Clarimycin (Clarithromycin)

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Clarimycin is an antibiotic used to treat various types of infections. It is effective in most infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against a bacteria known as H. pylori, which is associated with peptic ulcer disease.

Other names for this medication:
Althromicin, Bacterfin, Biclar, Ciclinil, Cidoclar, Clacina, Clacine, Clamycin, Clarimac, Claripen, Claritab, Clarithromycin, Clariva, Clarix, Clarogen, Claron, Clarosip, Claryl, Clasine, Clormicin, Derizic, Euromicina, Finasept, Gervaken, Helozym, Kalecin, Klabet, Klabion, Klarimax, Klerimed, Kleromicin, Laricid, Larithro, Maclar, Mononaxy, Monozeclar, Onexid, Synclar, Veclam, Xylar, Zeclaren

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Noroxin, Rulide, Avelox, Ceftin, Terramycin, Zithromax, Omnicef, Chloromycetin

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Also known as: Clarithromycin


Clarimycin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Clarimycin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Clarimycin Filmtab and Clarimycin Granules are recommended as the primary agents. Clarimycin Filmtab and Clarimycin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Clarimycin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Clarimycin therapy should continue if clinical response is observed. Clarimycin can be discontinued when the patient is considered at low risk of disseminated infection.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store Clarimycin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clarimycin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Clarimycin are:

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TTN5 is most closely related in sequence to the ARL2 class of ARF-like proteins isolated from humans, rats, and mice. A comparative study on feature selection methods for drug discovery. The objective of this project is to study the characteristics of trunk muscle recruitment strategies experimentally observed for scoliotic subjects using a finite element model of the trunk. This amphiphile performs two roles: first, it binds and then releases DNA, and second, as an anionic multicharged amphiphile, it destabilizes lipid bilayers. Gemcitabine chemotherapy may be more effective and allow longer survivals in patients with clinical characters of smaller tumor size and normal serum BUN level at diagnosis. Although dimensional changes in investment and casting are by volume, no evidence of anisotropic expansion of castings in a vertical direction was found. Apoptosis is the most desirable type of programmed cell death in cancer therapy. Horses were medicated with medetomidine (0.005 mg/kg, IV) and anesthetized with ketamine (2.5 mg/kg, IV) and midazolam (0.04 mg/kg, IV).

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Electromyography (EMG) onsets of vastus medialis obliquus (VMO), vastus lateralis (VL), tibialis anterior and soleus were assessed before and after the six week standardised treatment programs. EMG activity also increased during a test period, reflecting increased mobilization to maintain performance. Gastrointestinal (GI) motility results from the coordinated actions of enteric neurons, interstitial cells of Cajal (ICC), and smooth muscle cells. Effects of changes in coronary stenosis on left ventricular diastolic filling assessed with pulsed Doppler echocardiography. Comparative evaluation of the VITEK 2, disk diffusion, etest, broth microdilution, and agar dilution susceptibility testing methods for colistin in clinical isolates, including heteroresistant Enterobacter cloacae and Acinetobacter baumannii strains. These conserved B-cell and T-cell epitopes can be helpful in developing effective vaccines against HCV and thus limiting threats of HCV infection in Pakistan. A total of 199 streptococci isolated from feces of healthy chickens, pigs, and beef cattle and 26 human clinical isolates were tested for resistance to kanamycin, streptomycin, tetracycline, erythromycin, and lincomycin. Nine drugs that were granted pediatric exclusivity were selected.

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We investigated cleocin dose iv trends in acute urinary retention (AUR) associated with BPH in a large, population-based cohort. Hospital born neonates transferred to the neonatal unit after birth and available in the unit 48 hours later comprised the study group. Cytosolic phospholipase A(2) (cPLA(2)) plays a key role in the release of arachidonic acid as the substrate of cyclooxygenase-1 (COX-1) or COX-2. No reduction in the T-helper/T-suppressor cell ratio could be demonstrated for the group as a whole, but in the 9 patients with an Injury Severity Score (ISS) of more than 16 a significant reduction in ratio from median 1.5 to 0.8 was found. An increase in the activities of ADM in the short and median term application of clonidine and of 7-ERO-D in the long term application was detected.

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Dynamic contrast-enhanced MR images may provide informative data about the nature of enlarged MLNs in the preoperative assessment of lung carcinoma. Serial functional affinity of autoantibodies in anti-glomerular basement membrane disease. Clopidogrel for prevention of major cardiac events after coronary stent implantation: 30-day and 6-month results in patients with smaller stents. This conclusion is in agreement with a suggestion (put forward in our earlier publications) that K15-type inhibitors are bound to PS-2 reaction center, replacing Q(A) in its binding site. CE lesions attenuated conditioned freezing and corticosterone responses to both tone and context. Isotropic-nematic phase transition in athermal solutions of rod-coil diblock copolymers. Mechanism for transforming growth factor beta regulation of alpha mRNA in lipopolysaccharide-stimulated B cells.

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MRI and surgical reports were then compared for the presence and location of deltoid ligament tears. The alpha 1-adrenoceptor antagonist doxazosin has been compared with placebo in 40 elderly hypertensive patients (mean age 71.4 years). Raman scattering studies sumycin suspension drug category of InP nanostructures created by MeV Sb ion implantation. Sulfa drugs as inhibitors of carbonic anhydrase: new targets for the old drugs. A cohort study of radiographic alveolar bone loss during adolescence. Chemical and genetic data indicated that all plasmids code for a hydroxamate-mediated iron assimilation system. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. Improved drinking after a 7-year follow-up is associated with improved QoL even when considering other factors such as additional healthcare use and stressful life events. However, longer follow-up and larger series are needed to establish the efficacy of this approach.

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Although small differences were seen between the funded and unfunded groups, the major finding was that those applicants with prior research and publication experience were more likely to get funded, but both groups were highly motivated to seek an academic career. The combination of anticoagulant and antiplatelet therapy has only been proven to provide additional benefit over anticoagulants alone in patients with prosthetic heart valves. Past research has characterized the uninsured population in fairly static terms. At high concentrations of forskolin or with a combination of forskolin and isoproterenol, cyclic AMP levels were in excess of those needed to maximally activate protein kinase and lipolysis. Hypertension Treatment for Patients with Advanced Chronic Kidney Disease.

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Tetranectin binds hepatocyte growth factor and tissue-type plasminogen activator. Effects of lithium in vitro levaquin sinusitis dosage on noradrenaline-induced cyclic AMP accumulation in rat cortical slices after reserpine-induced supersensitivity. Letrozole, an aromatase inhibitor, is used frequently in the treatment of oestrogen receptor-positive breast cancer. The effect on lactose production of several external modulators of intracellular cyclic AMP was studied in rat mammary gland tissue slices and explants. In addition, since it has a simple and small drive unit, it does not obstruct surgeon or other surgery robots. The individual, unique tumor Ags, which characterize each single tumor, were described 50 years ago in rodents but their molecular characterization was limited to few of them and obtained during the last 20 years.

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Since, in the climacteric, subcutaneous fat has a positive impact on the secretion of oestrogens and thus on climacteric symptoms, the results of the present study may be interpreted as an effect of the psychosocial stress to which corpulent women are exposed in our society because they do not fit the beauty ideal typical of our culture. Acrolein was also measured in 40 end stage renal disease (ESRD) patients (before and after a hemodialysis session), and 40 control subjects. Application of microstructural measurements to the analysis of densification kinetics is also discussed. Simulation results and experiment results show the efficiency of the control strategy and validates the method applied to the pump. We describe a patient who developed CHS three weeks after CAS with status epilepticus. Because of the rarity and the poor prognosis of patients with PAH, as well as the requirement of close monitoring of bosentan (due to its potential of causing liver dysfunction and its teratogenic effects), bosentan is currently available only through a special access program and is distributed by certain selected pharmacies.

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