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Chloromycetin (Chloramphenicol)
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Chloromycetin

Chloromycetin is an antibiotic. It's mainly used to treat eye infections (such as conjunctivitis) and sometimes ear infections. Chloromycetin comes as eye drops or eye ointment. These are available on prescription or to buy from pharmacies.

Other names for this medication:
Chloramphenicol, Chloroptic, Fenicol, Sopamycetin

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Also known as: Chloramphenicol

Description

Chloramphenicol is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth.

Chloramphenicol is used to treat serious infections in different parts of the body. It is sometimes given with other antibiotics. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections.

Chloramphenicol should only be used for serious infections in which other medicines do not work. This medicine may cause some serious side effects, including blood problems and eye problems. Symptoms of the blood problems include pale skin, sore throat and fever, unusual bleeding or bruising, and unusual tiredness or weakness. You and your doctor should talk about the good this medicine will do as well as the risks of taking it.

Chloramphenicol is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Powder for Solution

Dosage

Chloromycetin, like other potent drugs, should be prescribed at recommended doses known to have therapeutic activity. Administration of 50 mg/kg/day in divided doses will produce blood levels of the magnitude to which the majority of susceptible microorganisms will respond.

As soon as feasible an oral dosage form of another appropriate antibiotic should be substituted for intravenous Chloromycetin sodium succinate.

The following method of administration is recommended: Intravenously as a 10% (100 mg/mL) solution to be injected over at least a one-minute interval. This is prepared by the addition of 10 mL of an aqueous diluent such as water for injection or 5% dextrose injection.

Pediatric Patients with Immature Metabolic Processes. In young infants and other pediatric patients in whom immature metabolic functions are suspected, a dose of 25 mg/kg/day will usually produce therapeutic concentrations of the drug in the blood. In this group particularly, the concentration of the drug in the blood should be carefully followed by microtechniques. (Information available on request.)

Overdose

Overdosing by the patient is nearly impossible, as Chloromycetin is administered via IV delivery, however an overdose can still happen. The symptoms of an overdose are likely to include nausea, vomiting, mouth odor or unpleasant taste in the mouth, bone marrow suppression, and diarrhea.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Chloromycetin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

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This self-directed learning module highlights the obstacles faced by physicians treating chronic pain, in particular, the occasional lack of correlation between test results and symptoms, and the treatment pitfalls that may occur. Rapid expression of JAZ genes in response to JA is thought to attenuate JA responses, but little is known about the mechanisms by which newly synthesized JAZ proteins exert repression in the presence of the hormone. Identification and characterization of pheromone receptors and interplay between receptors and pheromone binding proteins in the diamondback moth, Plutella xyllostella. Amblyomma diemeniae, a new reptilian tick from Australia, with observations on variant formations of the clava in the genus Amblyomma. The urinary bladder during parturition: a consideration of its location, injury, and repair. Most of the arthroscopic portals described in the literature are posterior. In this technique, which requires a spatially coherent x-ray beam, a series of speckle patterns are measured at a large number of locations in a sample using various illumination sizes. Electron microscopic observations on the formation erythromycin 400 mg of elastic fibres in cultures of aortic medial cells and adventitial cells. minnesota mR 595 lipopolysaccharide (LPS) as antigen and by indirect IF with C. Schottky-enabled photoemission in a rf accelerator photoinjector: possible generation of ultralow transverse thermal-emittance electron beam.

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