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Azithromycinum (Azithromycin)
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Azithromycinum

Azithromycinum is used for treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. Azithromycinum is a macrolide antibiotic. It slows the growth of, or sometimes kills, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Other names for this medication:
Atizor, Azalid, Azatril, Azilide, Azimac, Azinom, Azithral, Azithrocin, Azithrocine, Azitrobac, Azitrolit, Azitrom, Azitrovid, Azomac, Azomex, Azrolid, Azycyna, Azyth, Bactexina, Bezanin, Goxil, Ilozin, Iramicina, Misultina, Novatrex, Respazit, Sumamed, Triamid, Trozocina, Ultrabac, Zetamax, Zifin, Zithrogen, Zithromac, Zithromycin, Zithrox, Zitrex, Zitrolab

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Also known as: Azithromycin

Description

Azithromycinum is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Azithromycinum inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Azithromycinum is the local analog (generic) of more famous drug Azithromycinum that has the same active substance (ingredient) and in result the same therapeutic effect. The main difference is that Azithromycinum is registered by a small local pharmaceutical company. The presence of the same active substance guarantees an identical pharmaceutical (therapeutic) effect on the body.

It is possible to buy Azithromycinum only in the pharmacies of the country where it is produced. With us, you can buy its more famous analog Azithromycinum, which is approved by the FDA and is sold worldwide. The same active substance guarantees the identity of the drugs and the identity of the pharmaceutical properties (they have only different names and packaging, in which they are sold).

Dosage

Generic Azithromycinum is available in: 250 mg (Low Dosage), 500 mg (Standard Dosage).

Generic Azithromycinum can be taken in tablets, liquid form, injections. You should take it by mouth with water.

To avoid problems with stomach, take tablets and liquid form with meals. Liquid Generic Azithromycinum form should be shook properly. Capsule is taken on empty stomach.

It is better to take Generic Azithromycinum every day at the same time.

Generic Azithromycinum treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions.

For children it is better to take into account child weight. In treatment of otitis media, take Generic Azithromycinum for 1-5 days.

For Adults: if you treat Pneumonia or Throat/Tonsil Infection the right dose is two tablets of 250 mg on the first day and then 250 mg once a day for 4 more days.

In prevention of MAC (mycobacterium avium complex) usual Generic Azithromycinum dosage is 1,200 mg for a week.

In treatment of skin or infections usual Generic Azithromycinum dosage is two tablets of 250 mg at the first day after you took one tablet of 250 mg for 4 days at the same time.

Overdose

If you overdose Azithromycinum and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azithromycinum overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Azithromycinum Tablet.

Side effects

The most common side effects associated with Azithromycinum are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make azithromycin less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking azithromycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Azithromycinum can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Primary structure and processing of gag and env gene products of human T-cell leukemia viruses HTLV-ICR and HTLV-IATK. For sub-10-mum nanowires, the polarization corresponding to maximum emission from the ends of the nanowire was found to be strongly dependent on the nanowire geometry and position of the vicinal nanoparticle. This hypothesis remains untested, however, due to persistent quiescence and scarcity of small cells in vitro. Variation of ultrasonic parameters with microstructure and material properties of trabecular bone: a 3D model simulation. The Cochrane Register of Controlled Trials (CENTRAL), the Cochrane Airways Group Specialised Register, MEDLINE and EMBASE databases were searched by the Cochrane Airways Group. From these results, we concluded that nicotine-induced relaxation of the guinea pig gallbladder is not mediated by the release of noradrenaline, nitric oxide (NO), prostaglandins, or a related substance, or by the activation of potassium channels, or by the stimulation of nicotinic cholinoceptors. Within 4 h, micromolar concentrations of L1AD3 almost totally inhibit thymidine incorporation, and ATP levels decrease significantly. This connection had been weakened in the 1980s, but concerns about the need for a competent workforce and new policy and practice challenges have reinvigorated this linkage. Of the two proteins proposed to target receptors for lysosomal degradation, sorting nexin 1 (SNX1) bound 10 and the C-terminal domain of G protein-coupled receptor-associated sorting protein bound 23 of the 59 tail proteins.

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