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Amotrex (Metronidazole)

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Amotrex is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

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Vantin, Myambutol, Chloromycetin, Omnicef, Rulide

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Also known as: Metronidazole


Amotrex (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Amotrex is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Use Generic Amotrex preparation for 5-10 days or if it is needed can take it longer. It is better to take Generic Amotrex 2-3 times a day at the same time on empty stomach. Do not stop taking Generic Amotrex suddenly.


Single oral doses of Amotrex, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Amotrex has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Amotrex overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store Amotrex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Amotrex out of the reach of children and away from pets.

Side effects

The most common side effects associated with Amotrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Psychotic Reaction with Disulfiram. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks.

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