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Amopen (Amoxicillin)
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Amopen

Amopen is an antibiotic. It's used to treat bacterial infections, such as chest infections (including pneumonia), dental abscesses and urinary tract infections (UTIs). It's used in children, often to treat ear infections and chest infections. The medicine is only available on prescription.

Other names for this medication:
Acimox, Alfamox, Amoclen, Amoram, Amoxicillin, Amoxicillinum, Amoxiline, Bristamox, Cipmox, Flemoxin, Flemoxon, Gimalxina, Larotid, Moxicillin, Novamoxin, Ospamox, Polymox, Raylina, Robamox, Servamox, Sintedix, Stacillin, Velamox, Wymox, Zimox

Similar Products:
Amoxil, Biaxin, Myambutol, Suprax, Cipro, Terramycin, Cefixime, Avelox, Ceftin, Flagyl

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Also known as: Amoxicillin

Description

Amopen is one of the best forms of antibiotic available today. It is used to treat infections caused by certain bacteria, including: infections of the ear, nose, and throat (pneumonia, bronchitis); infections of the genitourinary tract; infections of the skin and skin structure; infections of the lower respiratory tract; gonorrhea, acute uncomplicated (ano-genital and urethral infections) in male and females.

Amopen is also used before some surgery or dental work to prevent infection. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Amopen may also be used for other purposes not listed here.

Amopen acts by inhibiting the synthesis of bacterial cell wall and stopping the growth of bacteria.

Amopen is available in capsules.

Amopen is usually taken every 8 hours (three times a day). It can be taken with or without food.

The chewable tablets should be crushed or chewed thoroughly before they are swallowed. The tablets and capsules should be swallowed whole and taken with a full glass of water.

Take Amopen exactly as directed. Do not take more or less Amopen or take it more often than prescribed by your doctor. Do not stop taking Amopen without talking to your doctor. To clear up your infection completely, continue taking Amopen for the full course of treatment even if you feel better in a few days. Stopping Amopen too soon may cause bacteria to become resistant to antibiotics.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants 6 months and older, Children, and Adolescents: 80 to 90 mg/kg/day PO in divided doses every 12 hours is recommended by the American Academy of Pediatrics (AAP) as first-line therapy. Do not exceed 500 mg/dose if given every 8 hours or 875 mg/dose if given every 12 hours. AAP recommends a 10-day course for any child with severe disease and for all patients less than 2 years of age, regardless of severity. For children 2 to 5 years with mild to moderate disease, a 7-day course is acceptable. For children 6 years and older with mild to moderate disease, a 5- to 7-day course is acceptable. The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Infants 4 to 5 months: 80 to 90 mg/kg/day PO given in divided doses every 12 hours for 10 days was recommended by experts as first-line therapy in previous guidelines ; however, this age group is not addressed in the most current guidelines by the American Academy of Pediatrics (AAP). The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours or 25 mg/kg/day PO in divided doses every 12 hours for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours or 45 mg/kg/day PO in divided doses every 12 hours for severe infections.

Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours is the general FDA-approved dosing. Young infants are less capable of responding to infection, and the clinical manifestations of infection can be subtle. Because of the increased risk for complications of an undiagnosed systemic infection, every young infant presenting with a fever should be carefully evaluated.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amopen are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amopen.

Crystalluria, in some cases leading to renal failure, has also been reported after Amopen overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amopen crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amopen. Amopen may be removed from circulation by hemodialysis.

Storage

Generic: store at controlled room temperature (between 68 and 77 degrees F)

Amoxil: store at controlled room temperature (between 68 and 77 degrees F)

Moxatag: store at 77 degrees F; excursions permitted to 59-86 degrees F

Moxilin: store at controlled room temperature (between 68 and 77 degrees F)

Sumox: store at controlled room temperature (between 68 and 77 degrees F)

Trimox: store at controlled room temperature (between 68 and 77 degrees F)

Side effects

The most common side effects associated with Amopen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Dialysis, renal failure, renal impairment.

Use Amopen with caution in patients with renal impairment as the drug is substantially eliminated via renal mechanisms. Adjust dosage intervals in patients with CrCl 30 mL/min and in patients with renal failure. Dosage adjustments are also recommended for patients receiving dialysis. Do not use the extended release tablet in patients with CrCl 30 mL/min.

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The antioxidant-specific induction of expression directed by a reporter plasmid containing four AP-1 sites and the induction of AP-1 DNA-binding activity confirm previous results indicating that antioxidant treatment increases AP-1 activity. Detection of the retrovirus associated with AIDS is of value in identifying infants and children who may have unique medical and social problems that occur with AIDS. Neuroleptic malignant syndrome without fever: a report of three cases. The maximum combined lod score using all 114 affected patients was 28.6 with marker D5S393. Characterization and expression analysis of somatic embryogenesis receptor-like kinase genes from Phalaenopsis. Rate constants for hole transport are found to be dependent upon the identity of the secondary donor, the intervening bases, and the location of the secondary donor in the same strand as the primary donor or in the complementary strand.

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This generalization of prism adaptation effects at different neglect level symptoms suggests that the process of prism adaptation may activate brain functions related to multisensory integration and higher spatial representations. A Gittes test was performed to assess the chordee after penile degloving and preservation of the urethral plate. Auxin-induced growth of coleoptile segments can be inhibited by IgGanti-ABP, and the auxin response of split coleoptile sections is also strongly reduced by IgGanti-ABP. In angiosperms, the shoot apical meristem is at the origin of leaves and stems and is eventually transformed into the floral meristem. We determined the pattern of spread of metastatic lobular carcinoma in the chest, abdomen, and pelvis on CT. Temporomandibular joint articulations on working side during chewing in adult females with cross-bite and mandibular asymmetry. As an inhibitor of tyrosine kinase, imatinib mesylate is generally well tolerated and has been proved to be effective and safe during prolonged treatment of patients with advanced gastrointestinal stromal tumors. Also, we performed double-labeling experiments, injecting BDA in the CRNs and subunit B of the cholera toxin or Fluorogold in the spinal cord to verify that CRNs project onto reticulospinal neurons. To establish a convenient method for diagnosis of lethal avian influenza virus infection. We therefore consider the administration of flunarizine to be essential for the effective treatment of AHC in this case.

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The dynamics and structure of neonatal mortality in Bulgaria in the period of 1989-1998. Scanning probe microscopy conducted on individual nanorods demonstrated good electromechanical properties with a high piezoelectric magnitude of 41 pm V(-1). It is unclear which antibiotic is the best choice if antibiotics are indicated. Unique cardiopulmonary exercise test responses in overweight middle-aged adults with obstructive sleep apnea. From these measurements we conclude, that the new measurement scheme is robust against optical and photophysical artefacts which are inherent to standard FCS. Retrolisthesis is relatively rare but when present has been associated with increased back pain and impaired back function. Further characterization of this novel cytoskeletal linker will have important implications for understanding the physical interactions that stabilize and support cell-matrix, cell-cell, and intracellular cytoskeletal connections. We investigated in a porcine model whether measuring both the flow distal to an anastomosis and the graft transit time flow (TTF) gives a more accurate picture of the true blood flow in the left anterior descending artery (LAD) than graft TTF measurement alone.

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